2011
Diffusion Tensor Imaging in Autism Spectrum Disorders: Preliminary Evidence of Abnormal Neural Connectivity
Jou RJ, Jackowski AP, Papademetris X, Rajeevan N, Staib LH, Volkmar FR. Diffusion Tensor Imaging in Autism Spectrum Disorders: Preliminary Evidence of Abnormal Neural Connectivity. Australian & New Zealand Journal Of Psychiatry 2011, 45: 153-162. PMID: 21128874, PMCID: PMC3123660, DOI: 10.3109/00048674.2010.534069.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAmygdalaAnisotropyAtrophyBrain MappingChildChild Development Disorders, PervasiveCorpus CallosumDiffusion Tensor ImagingFrontal LobeHumansMaleNerve Fibers, MyelinatedNeural PathwaysTemporal Lobe
2010
Functional impact of global rare copy number variation in autism spectrum disorders
Pinto D, Pagnamenta AT, Klei L, Anney R, Merico D, Regan R, Conroy J, Magalhaes TR, Correia C, Abrahams BS, Almeida J, Bacchelli E, Bader GD, Bailey AJ, Baird G, Battaglia A, Berney T, Bolshakova N, Bölte S, Bolton PF, Bourgeron T, Brennan S, Brian J, Bryson SE, Carson AR, Casallo G, Casey J, Chung BH, Cochrane L, Corsello C, Crawford EL, Crossett A, Cytrynbaum C, Dawson G, de Jonge M, Delorme R, Drmic I, Duketis E, Duque F, Estes A, Farrar P, Fernandez BA, Folstein SE, Fombonne E, Freitag CM, Gilbert J, Gillberg C, Glessner JT, Goldberg J, Green A, Green J, Guter SJ, Hakonarson H, Heron EA, Hill M, Holt R, Howe JL, Hughes G, Hus V, Igliozzi R, Kim C, Klauck SM, Kolevzon A, Korvatska O, Kustanovich V, Lajonchere CM, Lamb JA, Laskawiec M, Leboyer M, Le Couteur A, Leventhal BL, Lionel AC, Liu XQ, Lord C, Lotspeich L, Lund SC, Maestrini E, Mahoney W, Mantoulan C, Marshall CR, McConachie H, McDougle CJ, McGrath J, McMahon WM, Merikangas A, Migita O, Minshew NJ, Mirza GK, Munson J, Nelson SF, Noakes C, Noor A, Nygren G, Oliveira G, Papanikolaou K, Parr JR, Parrini B, Paton T, Pickles A, Pilorge M, Piven J, Ponting CP, Posey DJ, Poustka A, Poustka F, Prasad A, Ragoussis J, Renshaw K, Rickaby J, Roberts W, Roeder K, Roge B, Rutter ML, Bierut LJ, Rice JP, Salt J, Sansom K, Sato D, Segurado R, Sequeira AF, Senman L, Shah N, Sheffield VC, Soorya L, Sousa I, Stein O, Sykes N, Stoppioni V, Strawbridge C, Tancredi R, Tansey K, Thiruvahindrapduram B, Thompson AP, Thomson S, Tryfon A, Tsiantis J, Van Engeland H, Vincent JB, Volkmar F, Wallace S, Wang K, Wang Z, Wassink TH, Webber C, Weksberg R, Wing K, Wittemeyer K, Wood S, Wu J, Yaspan BL, Zurawiecki D, Zwaigenbaum L, Buxbaum JD, Cantor RM, Cook EH, Coon H, Cuccaro ML, Devlin B, Ennis S, Gallagher L, Geschwind DH, Gill M, Haines JL, Hallmayer J, Miller J, Monaco AP, Nurnberger Jr J, Paterson AD, Pericak-Vance MA, Schellenberg GD, Szatmari P, Vicente AM, Vieland VJ, Wijsman EM, Scherer SW, Sutcliffe JS, Betancur C. Functional impact of global rare copy number variation in autism spectrum disorders. Nature 2010, 466: 368-372. PMID: 20531469, PMCID: PMC3021798, DOI: 10.1038/nature09146.Peer-Reviewed Original ResearchMeSH KeywordsCase-Control StudiesCell MovementChildChild Development Disorders, PervasiveCytoprotectionDNA Copy Number VariationsEuropeGene DosageGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansSignal TransductionSocial BehaviorConceptsUnderlying genetic determinantsRare copy number variationsCopy number variationsNovel genesWide analysisIndividual genomesASD candidatesCopy numberNumber variationsGenetic determinantsCellular proliferationFunctional impactDe novoGenomeGenesGeneticsDNAPathwayNovoMotilityProliferationAutism spectrum disorder
2000
How unspecified are disorders of children with a pervasive developmental disorder not otherwise specified? A study of social problems in children with PDD-NOS and ADHD
Luteijn E, Serra M, Jackson S, Steenhuis M, Althaus M, Volkmar F, Minderaa R. How unspecified are disorders of children with a pervasive developmental disorder not otherwise specified? A study of social problems in children with PDD-NOS and ADHD. European Child & Adolescent Psychiatry 2000, 9: 168-179. PMID: 11095039, DOI: 10.1007/s007870070040.Peer-Reviewed Original ResearchThe Children's Social Behavior Questionnaire for Milder Variants of PDD Problems: Evaluation of the Psychometric Characteristics
Luteijn E, Luteijn F, Jackson S, Volkmar F, Minderaa R. The Children's Social Behavior Questionnaire for Milder Variants of PDD Problems: Evaluation of the Psychometric Characteristics. Journal Of Autism And Developmental Disorders 2000, 30: 317-330. PMID: 11039858, DOI: 10.1023/a:1005527300247.Peer-Reviewed Original ResearchConceptsChildren's Social Behavior QuestionnaireSocial Behavior QuestionnaireChild Behavior ChecklistADHD groupAutism Behavior ChecklistPDDNOS groupBehavior ChecklistBehavior QuestionnaireGood psychometric qualitiesSignificant group differencesChild psychiatric disordersAutism groupInsight ScaleInsight problemBehavior problemsPsychometric qualitiesGroup differencesPsychometric characteristicsStereotypical behaviorsHigher scoresLarge sampleRigid behaviorComparison of groupsScale constructionChildrenToward a Developmental Operational Definition of Autism
Gillham J, Carter A, Volkmar F, Sparrow S. Toward a Developmental Operational Definition of Autism. Journal Of Autism And Developmental Disorders 2000, 30: 269-278. PMID: 11039854, DOI: 10.1023/a:1005571115268.Peer-Reviewed Original ResearchConceptsMental ageSocialization scoresChronological ageDevelopmental disordersVineland Adaptive Behavior ScalesLarge normative sampleDaily living skillsAdaptive behavior scoresTraditional diagnostic schemeDiagnosis of autismAdaptive Behavior ScalesAutism groupIntellectual functioningNormative sampleMaladaptive behaviorsChild communicationVineland scoresDevelopmental levelBasis of socializationSerious maladaptive behaviorsLiving skillsStandardized measuresAutismBehavior ScaleAdaptive behaviorBrief Report: Interrater Reliability of Clinical Diagnosis and DSM-IV Criteria for Autistic Disorder: Results of the DSM-IV Autism Field Trial
Klin A, Lang J, Cicchetti D, Volkmar F. Brief Report: Interrater Reliability of Clinical Diagnosis and DSM-IV Criteria for Autistic Disorder: Results of the DSM-IV Autism Field Trial. Journal Of Autism And Developmental Disorders 2000, 30: 163-167. PMID: 10832781, DOI: 10.1023/a:1005415823867.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAutistic DisorderChildChild Development Disorders, PervasiveChild, PreschoolDiagnosis, DifferentialFemaleHumansMaleObserver VariationPsychiatric Status Rating ScalesPsychometricsReproducibility of ResultsPDDNOS in DSM-IV.
Volkmar F, Shaffer D, First M. PDDNOS in DSM-IV. Journal Of Autism And Developmental Disorders 2000, 30: 74-5. PMID: 10819126.Peer-Reviewed Original Research
1999
Lessons from Secretin
Volkmar F. Lessons from Secretin. New England Journal Of Medicine 1999, 341: 1842-1845. PMID: 10588973, DOI: 10.1056/nejm199912093412412.Peer-Reviewed Original ResearchAutistic DisorderChildChild Development Disorders, PervasiveHumansJournalism, MedicalNostrumsSecretinPractice parameters for the assessment and treatment of children, adolescents, and adults with autism and other pervasive developmental disorders
Volkmar F, Cook E, Pomeroy J, Realmuto G, Tanguay P, Issues T. Practice parameters for the assessment and treatment of children, adolescents, and adults with autism and other pervasive developmental disorders. Journal Of The American Academy Of Child & Adolescent Psychiatry 1999, 38: 32s-54s. PMID: 10624084, DOI: 10.1016/s0890-8567(99)80003-3.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAutistic DisorderBehavior TherapyChildChild Development Disorders, PervasiveChild, PreschoolDiagnosis, DifferentialEducation, SpecialHumansInfantInfant, NewbornMental DisordersMiddle AgedPrevalenceConceptsPervasive developmental disorderDevelopmental disordersRelated pervasive developmental disordersPatterns of delayCognitive skillsBehavioral problemsSyndrome expressionTreatment of childrenAutismCoordination of servicesPractice parametersTreatment modalitiesSustained interventionsMental retardationIndividualsDisordersClinical careAdolescentsDevianceSkillsFirst yearChildrenCareAdultsInterventionSummary of the Practice Parameters for the Assessment and Treatment of Children, Adolescents, and Adults With Autism and Other Pervasive Developmental Disorders
Volkmar F, Cook E, Pomeroy J, Realmuto G, Tanguay P. Summary of the Practice Parameters for the Assessment and Treatment of Children, Adolescents, and Adults With Autism and Other Pervasive Developmental Disorders. Journal Of The American Academy Of Child & Adolescent Psychiatry 1999, 38: 1611-1615. PMID: 10596264, DOI: 10.1097/00004583-199912000-00028.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildChild Development Disorders, PervasiveChild PsychiatryChild, PreschoolHumansConceptsPervasive developmental disorderDevelopmental disordersRelated pervasive developmental disordersTreatment of childrenPatterns of delayCognitive skillsBehavioral problemsSyndrome expressionAutismAdolescentsDisordersChildrenCoordination of servicesPractice parametersSustained interventionsTreatment modalitiesTreatment recommendationsMental retardationIndividualsClinical careDevianceSkillsFirst yearCliniciansTreatmentThe Screening and Diagnosis of Autistic Spectrum Disorders
Filipek P, Accardo P, Baranek G, Cook E, Dawson G, Gordon B, Gravel J, Johnson C, Kallen R, Levy S, Minshew N, Prizant B, Rapin I, Rogers S, Stone W, Teplin S, Tuchman R, Volkmar F. The Screening and Diagnosis of Autistic Spectrum Disorders. Journal Of Autism And Developmental Disorders 1999, 29: 439-484. PMID: 10638459, DOI: 10.1023/a:1021943802493.Peer-Reviewed Original ResearchMeSH KeywordsAsperger SyndromeAutistic DisorderChildChild Development Disorders, PervasiveChild, PreschoolDiagnosis, DifferentialFemaleHumansInfantMaleNeuropsychological TestsPersonality AssessmentPsychiatric Status Rating ScalesConceptsEvaluation of autismMultidisciplinary consensus panelRoutine developmental surveillanceChild Neurology SocietyAppropriate diagnosisEarly suspicionConsensus panelPractice parametersDevelopmental surveillanceEarly interventionAmerican AcademyDiagnosisNational InstituteAutistic spectrum disorderSpectrum disorderRelevant scientific articlesDetailed recommendationsAutismA Normed Study of Face Recognition in Autism and Related Disorders
Klin A, Sparrow S, de Bildt A, Cicchetti D, Cohen D, Volkmar F. A Normed Study of Face Recognition in Autism and Related Disorders. Journal Of Autism And Developmental Disorders 1999, 29: 499-508. PMID: 10638462, DOI: 10.1023/a:1022299920240.Peer-Reviewed Original ResearchConceptsFace recognition deficitsRecognition deficitsMental ageFace recognitionYoung childrenVerbal mental ageFace recognition abilityNonverbal mental ageGeneral cognitive capacityOverall cognitive abilityChronological agePervasive developmental disorderVerbal abilityNonverbal intelligenceCognitive abilitiesTask demandsCognitive capacityTask performanceComparison taskAutistic groupProcessing peculiaritiesAutismDevelopmental disordersRecognition abilityOlder childrenHigher-Functioning Pervasive Developmental Disorders: Rates and Patterns of Psychotropic Drug Use
MARTIN A, SCAHILL L, KLIN A, VOLKMAR F. Higher-Functioning Pervasive Developmental Disorders: Rates and Patterns of Psychotropic Drug Use. Journal Of The American Academy Of Child & Adolescent Psychiatry 1999, 38: 923-931. PMID: 10405512, DOI: 10.1097/00004583-199907000-00024.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAutistic DisorderCentral Nervous System AgentsChildChild Development Disorders, PervasiveConnecticutDrug Therapy, CombinationDrug UtilizationFemaleHumansMaleSyndromeConceptsPsychotropic drug useHigher-functioning pervasive developmental disordersPervasive developmental disorderTarget symptomsDrug useMedication use patternsPsychotropic medication useDevelopmental disordersMedication history informationMore medicationsMedication useClinical presentationPsychiatric comorbidityClinical variablesPsychotropic agentsDrug classesClinical heterogeneityDisordersSymptomsSubjectsAsperger's disorderFull Scale IQComorbiditiesMedicationsAntidepressantsAsk the Editor
Volkmar F. Ask the Editor. Journal Of Autism And Developmental Disorders 1999, 29: 185-186. PMID: 10382142, DOI: 10.1023/a:1023009230857.Peer-Reviewed Original ResearchExploring the Boundaries of Pervasive Developmental Disorder Not Otherwise Specified: Analyses of Data from the DSM-IV Autistic Disorder Field Trial
Buitelaar J, Van der Gaag R, Klin A, Volkmar F. Exploring the Boundaries of Pervasive Developmental Disorder Not Otherwise Specified: Analyses of Data from the DSM-IV Autistic Disorder Field Trial. Journal Of Autism And Developmental Disorders 1999, 29: 33-43. PMID: 10097993, DOI: 10.1023/a:1025966532041.Peer-Reviewed Original ResearchMultiplex Developmental Disorders: The Role of Communication in the Construction of a Self
Paul R, Cohen D, Klin A, Volkmar F. Multiplex Developmental Disorders: The Role of Communication in the Construction of a Self. Child And Adolescent Psychiatric Clinics Of North America 1999, 8: 189-202. PMID: 9894036, DOI: 10.1016/s1056-4993(18)30203-7.Peer-Reviewed Original ResearchMeSH KeywordsChildChild Development Disorders, PervasiveChild, PreschoolCommunication DisordersDevelopmental DisabilitiesHumansInfantLanguage DevelopmentConceptsDevelopmental disordersDevelopment of languagePervasive developmental disorderChildren's abilityChild developmentCoherent senseRole of communicationCohesive senseCrucial strandIndividual aspectsRecent researchSelfDisordersSuch disordersChildrenVariety of aspectsAbilitySenseAspectsLanguageCommunication
1998
Brief Report: The Development of the Children's Social Behavior Questionnaire: Preliminary Data
Luteijn E, Jackson S, Volkmar F, Minderaa R. Brief Report: The Development of the Children's Social Behavior Questionnaire: Preliminary Data. Journal Of Autism And Developmental Disorders 1998, 28: 559-565. PMID: 9932242, DOI: 10.1023/a:1026060330122.Peer-Reviewed Original ResearchChildChild Development Disorders, PervasiveDiagnosis, DifferentialFemaleHumansMalePersonality AssessmentPsychiatric Status Rating ScalesPsychometricsReproducibility of ResultsSocial BehaviorHow Commonly Are Known Medical Conditions Associated with Autism?
Barton M, Volkmar F. How Commonly Are Known Medical Conditions Associated with Autism? Journal Of Autism And Developmental Disorders 1998, 28: 273-278. PMID: 9711483, DOI: 10.1023/a:1026052417561.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAutistic DisorderCentral Nervous System DiseasesChi-Square DistributionChildChild Development Disorders, PervasiveChild, PreschoolComorbidityFemaleHumansIntellectual DisabilityMalePrevalenceRetrospective StudiesAsk the Editor
Volkmar F. Ask the Editor. Journal Of Autism And Developmental Disorders 1998, 28: 269-270. PMID: 9656140, DOI: 10.1023/a:1026033808784.Peer-Reviewed Original ResearchAutistic DisorderChildChild Development Disorders, PervasiveDevelopmental DisabilitiesDiagnosis, DifferentialHumansMalePrognosisPsychiatric Status Rating Scales
1997
Risperidone Treatment of Children and Adolescents With Pervasive Developmental Disorders: A Prospective, Open-Label Study
MCDOUGLE C, HOLMES J, BRONSON M, ANDERSON G, VOLKMAR F, PRICE L, COHEN D. Risperidone Treatment of Children and Adolescents With Pervasive Developmental Disorders: A Prospective, Open-Label Study. Journal Of The American Academy Of Child & Adolescent Psychiatry 1997, 36: 685-693. PMID: 9136504, DOI: 10.1097/00004583-199705000-00020.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdolescent BehaviorChildChild BehaviorChild Development Disorders, PervasiveDopamine AntagonistsFemaleHumansMaleProspective StudiesRisperidoneSerotonin AntagonistsTreatment OutcomeConceptsPervasive developmental disorderDevelopmental disordersRisperidone treatmentClinical Global Impression ScaleOpen-label studyOpen-label trialPlacebo-controlled studyCommon side effectsEfficacy of risperidoneShort-term safetyGlobal Impression ScaleGlobal improvement itemBehavioral ratingsChildhood disintegrative disorderSocial relatednessTreatment of childrenAsperger's disorderRepetitive behaviorsAutistic disorderBehavioral symptomsBaseline visitMean ageImpression ScaleAdolescentsOptimal dose