1994
Noradrenergic and adrenergic functioning in autism
Minderaa R, Anderson G, Volkmar F, Akkerhuis G, Cohen D. Noradrenergic and adrenergic functioning in autism. Biological Psychiatry 1994, 36: 237-241. PMID: 7986888, DOI: 10.1016/0006-3223(94)90605-x.Peer-Reviewed Original ResearchConceptsUrinary excretion rateNeurochemical assessmentVanillylmandelic acidAdrenergic functioningExcretion rateNormal control individualsUrinary excretionPlasma levelsNoradrenergic functioningMarked abnormalitiesNormal controlsGroup mean differencesControl groupControl individualsNorepinephrineMean differenceAutistic patients
1989
Neurochemical Study of Dopamine Functioning in Autistic and Normal Subjects
MINDERAA R, ANDERSON G, VOLKMAR F, AKKERHUIS G, COHEN D. Neurochemical Study of Dopamine Functioning in Autistic and Normal Subjects. Journal Of The American Academy Of Child & Adolescent Psychiatry 1989, 28: 190-194. PMID: 2925571, DOI: 10.1097/00004583-198903000-00007.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAutistic DisorderDopamineFemaleHomovanillic AcidHumansMalePhenothiazinesProlactinConceptsPlasma PRLPlasma prolactinHVA levelsUrinary HVANormal controlsNormal subjectsUrinary DA excretionUrinary HVA excretionHomovanillic acid levelsDose of neurolepticPlasma PRL valuesDopamine functioningDopamine excretionNeuroleptic doseHVA excretionNeuroleptic medicationDA excretionNeurochemical studiesPRL valuesPeripheral indicesExcretion rateAcid levelsHVAExcretionSignificant differencesWhole blood serotonin and tryptophan in autism: Temporal stability and the effects of medication
Minderaa R, Anderson G, Volkmar F, Harcherick D, Akkerhuis G, Cohen D. Whole blood serotonin and tryptophan in autism: Temporal stability and the effects of medication. Journal Of Autism And Developmental Disorders 1989, 19: 129-136. PMID: 2708296, DOI: 10.1007/bf02212724.Peer-Reviewed Original ResearchConceptsWhole blood serotoninPlatelet countMedicated groupBlood serotoninSex-matched normal controlsSignificant intraclass correlation coefficientsEffects of medicationWhole blood concentrationsAutistic groupIntraclass correlation coefficientMean percentage differenceBlood concentrationsNormal controlsNormal subjectsWhole bloodTRP valuesSerotoninTryptophan valuesYear periodGroupCountPercentage differenceMedicationsBlood