2007
A randomized, double-blind, placebo-controlled study of the safety and efficacy of intravenous MCC-135 as an adjunct to primary percutaneous coronary intervention in patients with acute myocardial infarction: Evaluation of MCC-135 for left ventricular salvage in acute myocardial infarction (EVOLVE)
Jang I, Weissman N, Picard M, Zile M, Pettigrew V, Shen S, Tatsuno J, Hibberd M, Tzivoni D, Wackers F, Investigators T. A randomized, double-blind, placebo-controlled study of the safety and efficacy of intravenous MCC-135 as an adjunct to primary percutaneous coronary intervention in patients with acute myocardial infarction: Evaluation of MCC-135 for left ventricular salvage in acute myocardial infarction (EVOLVE). American Heart Journal 2007, 155: 113.e1-113.e8. PMID: 18082500, DOI: 10.1016/j.ahj.2007.08.020.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryBenzenesulfonatesCardiac CatheterizationCombined Modality TherapyCoronary AngiographyDose-Response Relationship, DrugDouble-Blind MethodDrug Administration ScheduleElectrocardiographyFemaleFollow-Up StudiesHumansInfusions, IntravenousMaleMiddle AgedMyocardial InfarctionPiperazinesProbabilityReference ValuesRisk AssessmentSalvage TherapyStroke VolumeSurvival RateTreatment OutcomeVentricular Function, LeftConceptsPrimary percutaneous coronary interventionLeft ventricular ejection fractionST-elevation myocardial infarctionPrimary PCIMCC-135Percutaneous coronary interventionAcute myocardial infarctionInfarct sizeMyocardial infarctionDay 5Coronary interventionClinical outcomesCalcium overloadPreservation of LVEFAcute ST-elevation myocardial infarctionEnd pointTarget populationComposite clinical outcomeLeft Ventricular SalvagePlacebo-controlled studyPrimary end pointSecondary end pointsLow-dose groupVentricular ejection fractionHigh-dose group
2002
Pharmacologic stress perfusion imaging with adenosine: Role of simultaneous low-level treadmill exercise
Samady H, Wackers FJ, Joska TM, Zaret BL, Jain D. Pharmacologic stress perfusion imaging with adenosine: Role of simultaneous low-level treadmill exercise. Journal Of Nuclear Cardiology 2002, 9: 188-196. PMID: 11986564, DOI: 10.1067/mnc.2002.119973.Peer-Reviewed Original ResearchConceptsLow-level treadmill exerciseMyocardial perfusion imagingTreadmill exerciseElectrocardiographic changesAdverse effectsAdenosine myocardial perfusion imagingSestamibi single-photon emissionPharmacologic stress myocardial perfusion imagingStress myocardial perfusion imagingIschemic electrocardiographic changesLow-level exerciseMore adverse effectsUnfavorable side effectsSingle photon emissionAdenosine studyAdenosine TcMore patientsMyocardial ischemiaHemodynamic responseStress perfusionSide effectsPerfusion imagingTracer uptakePatientsMPI studies
1991
Adenosine or dipyridamole: Which is preferred for myocardial perfusion imaging?
Wackers F. Adenosine or dipyridamole: Which is preferred for myocardial perfusion imaging? Journal Of The American College Of Cardiology 1991, 17: 1295-1296. PMID: 2016446, DOI: 10.1016/s0735-1097(10)80138-x.Peer-Reviewed Original Research