2007
A randomized, double-blind, placebo-controlled study of the safety and efficacy of intravenous MCC-135 as an adjunct to primary percutaneous coronary intervention in patients with acute myocardial infarction: Evaluation of MCC-135 for left ventricular salvage in acute myocardial infarction (EVOLVE)
Jang I, Weissman N, Picard M, Zile M, Pettigrew V, Shen S, Tatsuno J, Hibberd M, Tzivoni D, Wackers F, Investigators T. A randomized, double-blind, placebo-controlled study of the safety and efficacy of intravenous MCC-135 as an adjunct to primary percutaneous coronary intervention in patients with acute myocardial infarction: Evaluation of MCC-135 for left ventricular salvage in acute myocardial infarction (EVOLVE). American Heart Journal 2007, 155: 113.e1-113.e8. PMID: 18082500, DOI: 10.1016/j.ahj.2007.08.020.Peer-Reviewed Original ResearchMeSH KeywordsAgedAngioplasty, Balloon, CoronaryBenzenesulfonatesCardiac CatheterizationCombined Modality TherapyCoronary AngiographyDose-Response Relationship, DrugDouble-Blind MethodDrug Administration ScheduleElectrocardiographyFemaleFollow-Up StudiesHumansInfusions, IntravenousMaleMiddle AgedMyocardial InfarctionPiperazinesProbabilityReference ValuesRisk AssessmentSalvage TherapyStroke VolumeSurvival RateTreatment OutcomeVentricular Function, LeftConceptsPrimary percutaneous coronary interventionLeft ventricular ejection fractionST-elevation myocardial infarctionPrimary PCIMCC-135Percutaneous coronary interventionAcute myocardial infarctionInfarct sizeMyocardial infarctionDay 5Coronary interventionClinical outcomesCalcium overloadPreservation of LVEFAcute ST-elevation myocardial infarctionEnd pointTarget populationComposite clinical outcomeLeft Ventricular SalvagePlacebo-controlled studyPrimary end pointSecondary end pointsLow-dose groupVentricular ejection fractionHigh-dose group
1985
Prognostic significance of normal quantitative planar thallium-201 stress scintigraphy in patients with chest pain
Wackers F, Russo D, Russo D, Clements J. Prognostic significance of normal quantitative planar thallium-201 stress scintigraphy in patients with chest pain. Journal Of The American College Of Cardiology 1985, 6: 27-30. PMID: 3159779, DOI: 10.1016/s0735-1097(85)80247-3.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseThallium-201 stress scintigraphyArtery diseaseStress scintigraphyPretest likelihoodCardiac eventsChest painPrognostic significanceQuantitative thallium-201 scintigraphyChest pain syndromeThallium-201 scintigraphyHigh pretest likelihoodLow pretest likelihoodBasis of symptomsAnginal complaintsMean followPain syndromeExcellent prognosisNormal findingsConsecutive seriesStress electrocardiographyNormal studiesPatientsScintigraphyDisease