Serial radionuclide assessment of doxorubicin cardiotoxicity in cancer patients with abnormal baseline resting left ventricular performance
Choi B, Berger H, Schwartz P, Alexander J, Wackers F, Gottschalk A, Zaret B. Serial radionuclide assessment of doxorubicin cardiotoxicity in cancer patients with abnormal baseline resting left ventricular performance. American Heart Journal 1983, 106: 638-643. PMID: 6613807, DOI: 10.1016/0002-8703(83)90080-7.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionVentricular ejection fractionCongestive heart failureLeft ventricular performanceVentricular performanceEjection fractionAbnormal baselineHeart failureDoxorubicin therapyDoxorubicin cardiotoxicityRadionuclide angiocardiographyAbnormal left ventricular ejection fractionFinal left ventricular ejection fractionAntecedent cardiovascular diseaseSerial radionuclide studiesFirst-pass radionuclide angiocardiographyIdentification of patientsUse of doxorubicinSafe discontinuationThoracic radiationVentricular functionCancer patientsCumulative doseCardiovascular diseaseRadionuclide assessment