1986
Effects of Cyclosporine and Cortisone on the Pathogenesis of Primary Infection with Cytomegalovirus in the Guinea Pig
MacGregor M, Lucia H, Vine W, FitzGerald P, Bia F. Effects of Cyclosporine and Cortisone on the Pathogenesis of Primary Infection with Cytomegalovirus in the Guinea Pig. The Journal Of Infectious Diseases 1986, 153: 503-510. PMID: 3005426, DOI: 10.1093/infdis/153.3.503.Peer-Reviewed Original ResearchConceptsPrimary infectionGuinea pigsTissue culture infectious dosesEffect of cyclosporineGuinea pig modelRate of isolationGuinea pig cytomegalovirusOral CsAImmunosuppressive agentsInflammatory responseInfectious dosesViral inclusionsPig modelDay 14Day 0CortisoneCytomegalovirusMinimal inflammatory responseCsALymphopeniaPathogenesisInfectionUntreated controlsAnimalsTissue
1985
Effects of Cyclosporine on the Pathogenesis of Primary Cytomegalovirus Infection in the Guinea Pig
Bia F, Lucia H, Bia M, Vine W, Tuttle A. Effects of Cyclosporine on the Pathogenesis of Primary Cytomegalovirus Infection in the Guinea Pig. Intervirology 1985, 24: 154-165. PMID: 2999030, DOI: 10.1159/000149635.Peer-Reviewed Original ResearchConceptsPrimary cytomegalovirus infectionGuinea pigsCytomegalovirus infectionPrimary CMV infectionEffect of cyclosporinePresence of CMVGuinea pig CMVGuinea pig modelInternal organsHartley guinea pigsTotal body weightUntreated controlsCMV isolationOral CsACMV infectionCsA administrationLymphocyte valuesLymphocytes/Inflammatory responseMean changeViral inclusionsBody weightPig modelDay 0CMV
1983
Histopathologic and ultrastructural studies of disseminated cytomegalovirus infection in strain 2 guinea pigs.
Fong C, Lucia H, Bia F, Hsiung G. Histopathologic and ultrastructural studies of disseminated cytomegalovirus infection in strain 2 guinea pigs. Laboratory Investigation 1983, 49: 183-94. PMID: 6308346.Peer-Reviewed Original ResearchConceptsStrain 2 guinea pigsGuinea pigsCytomegalovirus infectionSalivary glandsViral inclusionsCultured guinea pig cellsGuinea pig cytomegalovirus infectionDisseminated cytomegalovirus infectionSevere disseminated diseaseHigh mortality rateUseful animal modelGland duct cellsSalivary gland duct cellsDisseminated diseaseGuinea pig cellsHistologic examinationElectron microscopic examinationAnimal modelsMortality rateVirus inoculationGross lesionsInfectious virusVisceral tissuesPig cellsIntranuclear inclusions
1980
Ultrastructural development and persistence of guinea pig cytomegalovirus in duct cells of guinea pig submaxillary gland
Fong C, Bia F, Hsiung G. Ultrastructural development and persistence of guinea pig cytomegalovirus in duct cells of guinea pig submaxillary gland. Archives Of Virology 1980, 64: 97-108. PMID: 6247997, DOI: 10.1007/bf01318013.Peer-Reviewed Original Research