1987
Effects of Cyclosporine on Chronic Cytomegalovirus Infection in the Guinea Pig
Markham D, Griffith B, Lerner E, Lucia H, Bia F. Effects of Cyclosporine on Chronic Cytomegalovirus Infection in the Guinea Pig. Intervirology 1987, 28: 171-180. PMID: 2836336, DOI: 10.1159/000150013.Peer-Reviewed Original ResearchConceptsCytomegalovirus infectionLymphoid tissueGuinea pig cytomegalovirus infectionDetectable systemic diseaseGPCMV-infected animalsChronic cytomegalovirus infectionEffect of cyclosporineCMV isolationImmunosuppressed groupSystemic diseaseGuinea pigsExperimental animalsCs immunosuppressionCyclosporineIsolation rateDrug vehicleInfectionTissueAnimalsImmunosuppressionGavageDisease
1983
Histopathologic and ultrastructural studies of disseminated cytomegalovirus infection in strain 2 guinea pigs.
Fong C, Lucia H, Bia F, Hsiung G. Histopathologic and ultrastructural studies of disseminated cytomegalovirus infection in strain 2 guinea pigs. Laboratory Investigation 1983, 49: 183-94. PMID: 6308346.Peer-Reviewed Original ResearchConceptsStrain 2 guinea pigsGuinea pigsCytomegalovirus infectionSalivary glandsViral inclusionsCultured guinea pig cellsGuinea pig cytomegalovirus infectionDisseminated cytomegalovirus infectionSevere disseminated diseaseHigh mortality rateUseful animal modelGland duct cellsSalivary gland duct cellsDisseminated diseaseGuinea pig cellsHistologic examinationElectron microscopic examinationAnimal modelsMortality rateVirus inoculationGross lesionsInfectious virusVisceral tissuesPig cellsIntranuclear inclusions