Epigenome-Wide Meta-Analysis Reveals Differential DNA Methylation Associated With Estimated Glomerular Filtration Rate Among African American Men With HIV
Chen J, Hui Q, Wang Z, Wilson F, So-Armah K, Freiberg M, Justice A, Xu K, Zhao W, Ammous F, Smith J, Kardia S, Gwinn M, Marconi V, Sun Y. Epigenome-Wide Meta-Analysis Reveals Differential DNA Methylation Associated With Estimated Glomerular Filtration Rate Among African American Men With HIV. Kidney International Reports 2023, 8: 1076-1086. PMID: 37180517, PMCID: PMC10166785, DOI: 10.1016/j.ekir.2023.02.1085.Peer-Reviewed Original ResearchEpigenome-wide association studiesDNA methylationGlomerular filtration rateRenal diseaseFinger protein 20Differential DNA methylationKidney functionFiltration rateAfrican ancestryEnd-stage renal diseaseDifferent populationsProtein 20Ancestral groupsRenal disease progressionAssociation studiesDifferent ancestral groupsMethylationAfrican American menAncestryEuropean ancestryStudy cohortIndependent African American samplesDisease progressionFaster progressionGeneral population