2019
Bisphosphonate-loaded Bone Cement as a Local Adjuvant Therapy for Giant Cell Tumor of Bone
Greenberg DD, Lee FY. Bisphosphonate-loaded Bone Cement as a Local Adjuvant Therapy for Giant Cell Tumor of Bone. American Journal Of Clinical Oncology 2019, 42: 231-237. PMID: 30811352, DOI: 10.1097/coc.0000000000000504.Peer-Reviewed Original ResearchConceptsGiant cell tumorAdjuvant therapyLocal adjuvant therapySystemic side effectsAvascular necrosisCell tumorsSide effectsMusculoskeletal Tumor Society scoreOsteoclast-like giant cellsAggressive bone resorptionTherapeutic Level IVHigh-speed burringLocal recurrence rateAtypical femur fracturesLevel of evidenceTraditional adjuvant therapyBone cementAtypical fracturesSystemic bisphosphonatesPulmonary metastasesSociety ScoreCurettage proceduresRecurrence rateFemur fracturesPolymethylmethacrylate bone cement
1999
Chondrosarcoma of bone: an assessment of outcome.
Lee FY, Mankin HJ, Fondren G, Gebhardt MC, Springfield DS, Rosenberg AE, Jennings LC. Chondrosarcoma of bone: an assessment of outcome. Journal Of Bone And Joint Surgery 1999, 81: 326-38. PMID: 10199270, DOI: 10.2106/00004623-199903000-00004.Peer-Reviewed Original ResearchConceptsGrade 3 lesionsIntralesional resectionLocal recurrenceHistological gradePostoperative adjuvant radiationLimb-sparing proceduresPredictor of metastasisGroup of patientsHigh-grade lesionsLow-grade tumorsPredictors of outcomeHigh-grade tumorsAssessment of outcomesAdjuvant radiationPathological fracturesRecurrent diseasePulmonary metastasesDistant metastasisAdjunctive chemotherapyMarginal resectionMean ageMean durationPelvic locationPrevalent siteGrade 3