Liver histology and HBV DNA levels in chronically HBV infected patients with persistently normal alanine aminotransferase.
Montazeri G, Rahban M, Mohamadnejad M, Zamani F, Hooshyar A, Fazlolahi A, Abedian S, Ghoujeghi F, Estakhri A, Montazeri F, Razjoyan H, Mamarabadi M, Alimohamadi M, Tavangar SM, Malekzadeh R. Liver histology and HBV DNA levels in chronically HBV infected patients with persistently normal alanine aminotransferase. Archives Of Iranian Medicine 2010, 13: 193-202. PMID: 20433223.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAlanine TransaminaseAnalysis of VarianceBiopsy, NeedleCohort StudiesDNA, ViralFollow-Up StudiesHepatitis B e AntigensHepatitis B virusHepatitis B, ChronicHumansImmunohistochemistryLinear ModelsLiver Function TestsMaleMiddle AgedMonitoring, PhysiologicMultivariate AnalysisReference ValuesRetrospective StudiesRisk AssessmentROC CurveSensitivity and SpecificitySeverity of Illness IndexTime FactorsConceptsBaseline HBV DNAChronic HBV infectionHBV DNA levelsHBeAg-negative chronic HBV infectionNegative chronic HBV infectionNormal alanine aminotransferase levelsNormal alanine aminotransferaseAlanine aminotransferase levelsHBV DNAHBV infectionTotal scoreAminotransferase levelsHistological activityAlanine aminotransferaseMedian levelsMedian baseline HBV DNADNA levelsAssociation of histologySecond liver biopsyActive liver diseaseMedian time intervalAdjusted odds ratioLog10 IULiver histologyLiver biopsy