Featured Publications
Severe aortic stenosis detection by deep learning applied to echocardiography
Holste G, Oikonomou E, Mortazavi B, Coppi A, Faridi K, Miller E, Forrest J, McNamara R, Ohno-Machado L, Yuan N, Gupta A, Ouyang D, Krumholz H, Wang Z, Khera R. Severe aortic stenosis detection by deep learning applied to echocardiography. European Heart Journal 2023, 44: 4592-4604. PMID: 37611002, PMCID: PMC11004929, DOI: 10.1093/eurheartj/ehad456.Peer-Reviewed Original ResearchConceptsSevere aortic stenosis
2019
Meta-Analysis of Transthoracic Echocardiography Versus Cardiac Magnetic Resonance for the Assessment of Aortic Regurgitation After Transcatheter Aortic Valve Implantation
Papanastasiou CA, Kokkinidis DG, Jonnalagadda AK, Oikonomou EK, Kampaktsis PN, Garcia MJ, Myerson SG, Karamitsos TD. Meta-Analysis of Transthoracic Echocardiography Versus Cardiac Magnetic Resonance for the Assessment of Aortic Regurgitation After Transcatheter Aortic Valve Implantation. The American Journal Of Cardiology 2019, 124: 1246-1251. PMID: 31466694, DOI: 10.1016/j.amjcard.2019.07.036.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationCardiac magnetic resonanceSevere aortic regurgitationAortic regurgitationAortic valve implantationValve implantationPost-TAVI aortic regurgitationHierarchical summary receiver operator characteristic curveSeverity of ARLevel of agreementDiagnostic accuracyResidual aortic regurgitationReceiver operator characteristic curveOperator characteristic curveTransthoracic echocardiographyEchocardiographic assessmentMajor complicationsSummary receiver operator characteristic curveMagnetic resonanceAR assessmentElectronic databasesMeta-AnalysisSystematic reviewClinical settingKappa coefficientThe Prognostic Role of Late Gadolinium Enhancement in Aortic Stenosis A Systematic Review and Meta-Analysis
Papanastasiou CA, Kokkinidis DG, Kampaktsis PN, Bikakis I, Cunha DK, Oikonomou EK, Greenwood JP, Garcia MJ, Karamitsos TD. The Prognostic Role of Late Gadolinium Enhancement in Aortic Stenosis A Systematic Review and Meta-Analysis. JACC Cardiovascular Imaging 2019, 13: 385-392. PMID: 31326491, DOI: 10.1016/j.jcmg.2019.03.029.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementAortic stenosisCardiac magnetic resonanceCause mortalityGadolinium enhancementLGE-CMRSystematic reviewA Systematic ReviewStrongest univariate predictorsRandom-effects modelBaseline characteristicsHazard ratioPrognostic roleRisk stratificationAdverse outcomesPrognostic valueUnivariate predictorsPooled analysisMyocardial fibrosisInclusion criteriaCardiac diseaseRegional fibrosisPatientsElectronic databasesMeta-Analysis
2018
The predictive value of baseline pulmonary hypertension in early and long term cardiac and all-cause mortality after transcatheter aortic valve implantation for patients with severe aortic valve stenosis: A systematic review and meta-analysis
Kokkinidis DG, Papanastasiou CA, Jonnalagadda AK, Oikonomou EK, Theochari CA, Palaiodimos L, Karvounis HI, Armstrong EJ, Faillace RT, Giannakoulas G. The predictive value of baseline pulmonary hypertension in early and long term cardiac and all-cause mortality after transcatheter aortic valve implantation for patients with severe aortic valve stenosis: A systematic review and meta-analysis. Cardiovascular Revascularization Medicine 2018, 19: 859-867. PMID: 29724516, DOI: 10.1016/j.carrev.2018.03.015.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationElevated pulmonary artery pressurePulmonary artery pressureAortic valve stenosisSevere aortic valve stenosisSurgical aortic valve replacementBaseline pulmonary hypertensionPulmonary hypertensionAortic valve implantationArtery pressureCause mortalityHazard ratioSystematic reviewValve implantationValve stenosisRelative riskAssociation of PHBaseline pulmonary artery pressurePulmonary artery systolic pressureChronic obstructive pulmonary diseaseAortic valve replacementLate cardiac mortalityObstructive pulmonary diseaseRandom-effects modelMeta-regression analysis