2017
Fear extinction in an obsessive-compulsive disorder animal model: Influence of sex and estrous cycle
Reimer A, de Oliveira A, Diniz J, Hoexter M, Miguel E, Milad M, Brandão M. Fear extinction in an obsessive-compulsive disorder animal model: Influence of sex and estrous cycle. Neuropharmacology 2017, 131: 104-115. PMID: 29225044, DOI: 10.1016/j.neuropharm.2017.12.015.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderFear extinctionOCD patientsTreatment of OCDFear extinction retentionExtinction retention deficitsFear extinction trainingOCD pathophysiologyOCD-like symptomsAnterior cingulate cortexFear inhibitionExtinction retentionAccount sex differencesEstrous cycleExtinction trainingRetention deficitsRepetitive behaviorsDistinct neurotransmitter systemsMedial prefrontalUntreated OCD patientsCingulate cortexAnimal modelsSelf-grooming behaviorBrain areasEstrous cycle phase
2012
Outlining new frontiers for the comprehension of obsessive-compulsive disorder: a review of its relationship with fear and anxiety
Diniz J, Miguel E, de Oliveira A, Reimer A, Brandão M, de Mathis M, Batistuzzo M, Costa D, Hoexter M. Outlining new frontiers for the comprehension of obsessive-compulsive disorder: a review of its relationship with fear and anxiety. Brazilian Journal Of Psychiatry 2012, 34: 81-91. PMID: 22729451, DOI: 10.1590/s1516-44462012000500007.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderAnxiety disordersExpression of fearTypes of obsessionsAnimal anxiety modelsFear conditioningCortico-striatal pathwaysFunctional neuroimagingNeurobiological studiesAnxiety modelsOCD patientsOCD onsetExtinction processAnxietyRelevant dimensionsMost interventionsFearDisordersDegree of overlapTreatment responsePsychopathologyComprehensionNeurocircuitryFunctioningFuture studies
2000
CHARACTERIZATION OF TRICHOTILLOMANIA A Phenomenological Model with Clinical Relevance to Obsessive-Compulsive Spectrum Disorders
O'Sullivan R, Mansueto C, Lerner E, Miguel E. CHARACTERIZATION OF TRICHOTILLOMANIA A Phenomenological Model with Clinical Relevance to Obsessive-Compulsive Spectrum Disorders. Psychiatric Clinics Of North America 2000, 23: 587-604. PMID: 10986729, DOI: 10.1016/s0193-953x(05)70182-9.Peer-Reviewed Original Research
1997
CURRENT CONTROVERSIES AND FUTURE DIRECTIONS IN BASAL GANGLIA RESEARCH Integrating Basic Neuroscience and Clinical Investigation
Garcia-Cairasco N, Miguel E, Rauch S, Leckman J. CURRENT CONTROVERSIES AND FUTURE DIRECTIONS IN BASAL GANGLIA RESEARCH Integrating Basic Neuroscience and Clinical Investigation. Psychiatric Clinics Of North America 1997, 20: 945-962. PMID: 9443359, DOI: 10.1016/s0193-953x(05)70354-3.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBasal Ganglia DiseasesDisease Models, AnimalForecastingHumansNeurosciencesResearch Design