2023
Depression in mothers at childhood: Direct and indirect association with problematic gaming in late adolescence/young adulthood
Roza T, Rabelo-da-Ponte F, Spritzer D, Hoffmann M, Massuda R, Salum G, Miguel E, Rohde L, Pan P, Kessler F, Gadelha A, Passos I. Depression in mothers at childhood: Direct and indirect association with problematic gaming in late adolescence/young adulthood. Journal Of Psychiatric Research 2023, 159: 14-21. PMID: 36652752, DOI: 10.1016/j.jpsychires.2023.01.022.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultChildDepressionFemaleHumansLogistic ModelsMothersPsychopathologyVideo GamesYoung AdultConceptsAdolescence/young adulthoodMothers' depressionLate adolescence/young adulthoodRisk factorsSchool-based cohortYoung adulthoodMultiple confounding factorsLogistic regression modelsInverse probability weightsConfounding factorsExternalizing disordersInternalizing disordersDepressionPotential roleDisordersChildhoodMediatorsRegression modelsMothersSexAdulthoodInternalizing psychopathologySignificant mediatorMediation analysisAssociation
2022
Clinical characteristics of transformation obsessions in obsessive-compulsive disorder: A psychopathological study
Bettess Z, Albertella L, Destree L, Rosário M, Ferrão Y, Miguel E, Fontenelle L. Clinical characteristics of transformation obsessions in obsessive-compulsive disorder: A psychopathological study. Australian & New Zealand Journal Of Psychiatry 2022, 57: 130-139. PMID: 35303769, DOI: 10.1177/00048674221084241.Peer-Reviewed Original ResearchMeSH KeywordsCompulsive BehaviorHumansObsessive BehaviorObsessive-Compulsive DisorderPsychopathologySuicidal Ideation
2021
Longitudinal associations between positive attributes and psychopathology and their interactive effects on educational outcomes
Romani-Sponchiado A, Vidal-Ribas P, Bressan R, de Jesus Mari J, Miguel E, Gadelha A, Rohde L, Evans-Lacko S, Salum G, Hoffmann M. Longitudinal associations between positive attributes and psychopathology and their interactive effects on educational outcomes. European Child & Adolescent Psychiatry 2021, 32: 463-474. PMID: 34559317, DOI: 10.1007/s00787-021-01882-8.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChild, PreschoolEducational StatusFemaleHumansMaleMental DisordersProspective StudiesPsychopathologySchoolsConceptsEducational outcomesSchool dropoutCross-lagged panel modelBetter educational outcomesLow literacy abilityPositive attributesLiteracy abilitiesLongitudinal impactGeneral factorDropoutConduct symptomsSchoolingLiteracyLearningConduct problemsYouthConstructsOutcomesPanel modelLongitudinal associationsAttributes
2020
Gene expression changes associated with trajectories of psychopathology in a longitudinal cohort of children and adolescents
Ota V, Santoro M, Spindola L, Pan P, Simabucuro A, Xavier G, Vieira-Fonseca T, Zanardo E, dos Santos F, Schäfer J, Kulikowski L, Galante P, Asprino P, Brietzke E, Grassi-Oliveira R, Rohde L, Miguel E, Gadelha A, Mari J, Bressan R, Salum G, Belangero S. Gene expression changes associated with trajectories of psychopathology in a longitudinal cohort of children and adolescents. Translational Psychiatry 2020, 10: 99. PMID: 32184383, PMCID: PMC7078305, DOI: 10.1038/s41398-020-0772-3.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBrazilChildCohort StudiesGene ExpressionHumansMental DisordersPsychopathologyConceptsPsychiatric symptomsMental disordersChild Behavior Checklist total scoresTrajectories of psychopathologyBlood gene expression profilesHigh Risk Cohort StudyGeneral psychiatric symptomsBlood gene expression patternsPsychopathological trajectoriesCohort studyLow-low groupLongitudinal cohortPostmortem brainsGeneral psychopathologySpecific disordersTotal scoreGene expressionCBCL scoresGene expression changesGene expression profilesDisordersSymptomsRisk factors for obsessive–compulsive symptoms. Follow-up of a community-based youth cohort
Macul Ferreira de Barros P, do Rosário MC, Szejko N, Polga N, Requena GL, Ravagnani B, Fatori D, Batistuzzo MC, Hoexter MQ, Rohde LA, Polanczyk GV, Leckman JF, Miguel EC, de Alvarenga PG. Risk factors for obsessive–compulsive symptoms. Follow-up of a community-based youth cohort. European Child & Adolescent Psychiatry 2020, 30: 89-104. PMID: 32076869, DOI: 10.1007/s00787-020-01495-7.Peer-Reviewed Original ResearchConceptsObsessive-compulsive symptomsRisk factorsAbsence of breastfeedingOCS scoresBaseline anxiety disordersPotential risk factorsLarge community cohortLow socioeconomic statusRegression analysisMental health assessmentMaternal stress levelsLower intelligence quotientCommunity cohortChildhood adversityLower ageHigher OCS scoresAnxiety disordersPsychopathological factorsSocioeconomic statusGenetic factorsSignificant predictorsBaselineHealth assessmentScoresAge
2019
Effects of Maternal Psychopathology and Education Level on Neurocognitive Development in Infants of Adolescent Mothers Living in Poverty in Brazil
Shephard E, Fatori D, Mauro L, de Medeiros Filho M, Hoexter M, Chiesa A, Fracolli L, Brentani H, Ferraro A, Nelson C, Miguel E, Polanczyk G. Effects of Maternal Psychopathology and Education Level on Neurocognitive Development in Infants of Adolescent Mothers Living in Poverty in Brazil. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2019, 4: 925-934. PMID: 31345780, PMCID: PMC6863387, DOI: 10.1016/j.bpsc.2019.05.009.Peer-Reviewed Original ResearchConceptsLow maternal educationMaternal psychopathologyAttention-deficit/hyperactivity disorderMaternal anxietyNeurocognitive developmentInfant neurodevelopmentAdolescent mothersMaternal educationHyperactivity disorderInfant neurocognitive developmentMonths of ageResting-state electroencephalographyCluster-based permutation testingEducation levelOscillatory powerEarly brain developmentMaternal symptomsRisk factorsConnectivity alterationsEarly neurocognitive developmentOscillatory connectivityRelative theta powerFunctional connectivityBrain developmentPilot study
2018
Cross-Sectional and Longitudinal Associations of Temperament and Mental Disorders in Youth
Hoffmann M, Pan P, Manfro G, de Jesus Mari J, Miguel E, Bressan R, Rohde L, Salum G. Cross-Sectional and Longitudinal Associations of Temperament and Mental Disorders in Youth. Child Psychiatry & Human Development 2018, 50: 374-383. PMID: 30259212, DOI: 10.1007/s10578-018-0846-0.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderDisruptive behavior disordersEffortful controlLongitudinal associationsMental disordersWell-Being Behavior AssessmentEffects of temperamentConfirmatory factor analysisTemperament factorsHyperactivity disorderBifactor modelTemperament QuestionnaireAdjusted longitudinal analysesTemperamentBehavior disorderDistressFactor analysisParental interviewsPhobiaBehavior assessmentLongitudinal analysisYouthDisordersLogistic regression modelsEATQ
2017
Prevalence, clinical correlates and maternal psychopathology of deliberate self-harm in children and early adolescents: results from a large community study
Simioni A, Pan P, Gadelha A, Manfro G, Mari J, Miguel E, Rohde L, Salum G. Prevalence, clinical correlates and maternal psychopathology of deliberate self-harm in children and early adolescents: results from a large community study. Brazilian Journal Of Psychiatry 2017, 40: 48-55. PMID: 28832748, PMCID: PMC6899416, DOI: 10.1590/1516-4446-2016-2124.Peer-Reviewed Original ResearchConceptsAttention-deficit/hyperactivity disorderOppositional defiant disorderMaternal psychopathologyPsychiatric disordersClinical diagnosisCo-occurring psychiatric disordersAnxiety disordersHigh Risk Cohort StudyCommunity-based studyDiagnosis of depressionMaternal mood disordersMaternal anxiety disordersPotential confounding factorsLarge community studyChildhood psychiatric disordersChild's clinical diagnosisPrevalence of DSHCohort studyMiddle-income countriesClinical correlatesMood disordersPrevalence estimatesConfounding factorsAge groupsLogistic regressionPsychopathology and friendship in children and adolescents: disentangling the role of co-occurring symptom domains with serial mediation models
Manfro A, Pan P, Gadelha A, Fleck M, do Rosário M, Cogo-Moreira H, Affonseca-Bressan R, Mari J, Miguel E, Rohde L, Salum G. Psychopathology and friendship in children and adolescents: disentangling the role of co-occurring symptom domains with serial mediation models. European Child & Adolescent Psychiatry 2017, 26: 1377-1386. PMID: 28462487, DOI: 10.1007/s00787-017-0993-z.Peer-Reviewed Original ResearchConceptsSocial isolation
2016
Perinatal complications, lipid peroxidation, and mental health problems in a large community pediatric sample
Mansur R, Cunha G, Asevedo E, Zugman A, Rios A, Salum G, Pan P, Gadelha A, Levandowski M, Belangero S, Manfro G, Stertz L, Kauer-Sant’anna M, Miguel E, Bressan R, Mari J, Grassi-Oliveira R, Brietzke E. Perinatal complications, lipid peroxidation, and mental health problems in a large community pediatric sample. European Child & Adolescent Psychiatry 2016, 26: 521-529. PMID: 27785581, DOI: 10.1007/s00787-016-0914-6.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentBrazilChecklistChildChild Behavior DisordersCohort StudiesDevelopmental DisabilitiesFemaleHumansLipid PeroxidationLong Term Adverse EffectsMaleMalondialdehydeMental DisordersMental HealthOxidative StressPregnancyPsychopathologySocioeconomic FactorsThiobarbituric Acid Reactive SubstancesConceptsPerinatal complicationsMental health problemsCumulative exposureLipid peroxidationTBARS levelsChild Behavior ChecklistHealth problemsHigh Risk Cohort StudyMini-International Psychiatric InterviewYears of ageCBCL total problemsIndividual cumulative exposureEarly life environmentCohort studyCumulative risk indexSerum levelsPerinatal historyUnexposed groupExploratory mediation analysisPsychiatric interviewComplicationsPsychiatric disordersSocio-economic statusPediatric samplesOxidative stressConnectome hubs at resting state in children and adolescents: Reproducibility and psychopathological correlation
Sato J, Biazoli C, Salum G, Gadelha A, Crossley N, Vieira G, Zugman A, Picon F, Pan P, Hoexter M, Anés M, Moura L, Del’Aquilla M, Amaro E, Mcguire P, Rohde L, Miguel E, Bressan R, Jackowski A. Connectome hubs at resting state in children and adolescents: Reproducibility and psychopathological correlation. Developmental Cognitive Neuroscience 2016, 20: 2-11. PMID: 27288820, PMCID: PMC6987719, DOI: 10.1016/j.dcn.2016.05.002.Peer-Reviewed Original ResearchConceptsAnterior medial prefrontal cortexPsychiatric symptomsLarge-scale functional networksBrain hubsMental disordersHub regionsMedial prefrontal cortexResting-state fMRIFunctional cortical networksIndependent population-based samplesRight IPSPopulation-based sampleIntraparietal sulcusBrain networksPrefrontal cortexCortical networksIntegrative regionsFunctional networksAdolescentsLow centralitySymptomsChildrenDisordersReplicabilityInteresting target