2020
Testing the Stability and Validity of an Executive Dysfunction Classification Using Task-Based Assessment in Children and Adolescents
Manfro A, Pine D, Polanczyk G, Santoro M, Smoller J, Koenen K, Mari J, Pan P, Zugman A, Schäfer J, Belangero S, Gosmann N, Simioni A, Hoexter M, Miguel E, Gadelha A, Rohde L, Salum G. Testing the Stability and Validity of an Executive Dysfunction Classification Using Task-Based Assessment in Children and Adolescents. Journal Of The American Academy Of Child & Adolescent Psychiatry 2020, 60: 1501-1512. PMID: 33346031, PMCID: PMC10259767, DOI: 10.1016/j.jaac.2020.11.016.Peer-Reviewed Original ResearchConceptsPolygenic risk scoresPsychiatric diagnosisExecutive functionHigher schizophrenia polygenic risk scoresExecutive dysfunctionHigh Risk Cohort StudySmaller intracranial volumeHigher attention-deficit/hyperactivity disorderAttention-deficit/hyperactivity disorderSchizophrenia polygenic risk scoresCortical surface areaDichotomized ageCohort studyFunctional impairmentRisk scoreDomains of psychopathologyBrain regionsIntracranial volumeRelevant outcomesBrain structuresHyperactivity disorderCognitive tasksLatent class analysisLower chanceDiagnosis
2019
Is there any relationship between Neuroscience and Psychiatry
Farhat L, Hoexter M, Miguel E. Is there any relationship between Neuroscience and Psychiatry. Revista De Medicina 2019, 98: i-ii. DOI: 10.11606/issn.1679-9836.v98i4pi-ii.Peer-Reviewed Original ResearchRelative Age and Attention-Deficit/Hyperactivity Disorder: Data From Three Epidemiological Cohorts and a Meta-analysis
Caye A, Petresco S, de Barros A, Bressan R, Gadelha A, Gonçalves H, Manfro A, Matijasevich A, Menezes A, Miguel E, Munhoz T, Pan P, Salum G, Santos I, Kieling C, Rohde L. Relative Age and Attention-Deficit/Hyperactivity Disorder: Data From Three Epidemiological Cohorts and a Meta-analysis. Journal Of The American Academy Of Child & Adolescent Psychiatry 2019, 59: 990-997. PMID: 31442562, DOI: 10.1016/j.jaac.2019.07.939.Peer-Reviewed Original ResearchConceptsYounger ageADHD diagnosisMeta-AnalysisADHD symptomsPelotas cohortCommunity-based cohortPopulation-based cohortAttention-deficit/hyperactivity disorderHigh-risk studiesRelative young ageAttention-deficit/hyperactivity disorder (ADHD) symptomsWeb of ScienceHyperactivity disorder symptomsEpidemiology guidelinesEligible recordsRelative riskObservational studyHigh riskPsychiatric disordersEpidemiological cohortCohortSymptomsDiagnosisEffect estimatesHyperactivity disorderUse of Mental Health Services by Children With Mental Disorders in Two Major Cities in Brazil
Fatori D, Salum G, Rohde L, Pan P, Bressan R, Evans-Lacko S, Polanczyk G, Miguel E, Graeff-Martins A. Use of Mental Health Services by Children With Mental Disorders in Two Major Cities in Brazil. Psychiatric Services 2019, 70: 337-341. PMID: 30651056, DOI: 10.1176/appi.ps.201800389.Peer-Reviewed Original ResearchConceptsMental health servicesMental disordersUnmet needHealth servicesHigh Risk Cohort StudyCombination of psychotherapyMental health treatmentChildren ages 6Cohort studyHealth treatmentCommunity studyAge 6DisordersHealth careLifetime useWhite childrenChildrenHigh rateTreatmentCurrent studyPorto AlegreSao PauloMedicationsPsychotherapyDiagnosis
2017
Gene expression in blood of children and adolescents: Mediation between childhood maltreatment and major depressive disorder
Spindola L, Pan P, Moretti P, Ota V, Santoro M, Cogo-Moreira H, Gadelha A, Salum G, Manfro G, Mari J, Brentani H, Grassi-Oliveira R, Brietzke E, Miguel E, Rohde L, Sato J, Bressan R, Belangero S. Gene expression in blood of children and adolescents: Mediation between childhood maltreatment and major depressive disorder. Journal Of Psychiatric Research 2017, 92: 24-30. PMID: 28384542, DOI: 10.1016/j.jpsychires.2017.03.015.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentChildChild AbuseCohort StudiesDepressive Disorder, MajorFemaleGene ExpressionGenetic TestingHumansHypothalamo-Hypophyseal SystemInterleukin-1betaMaleModels, BiologicalPeptide FragmentsPituitary-Adrenal SystemReceptors, GlucocorticoidReceptors, Tumor Necrosis Factor, Type IResidence CharacteristicsRNA, MessengerTumor Necrosis Factor-alphaConceptsMajor depressive disorderBlood of childrenDepressive disorderChildhood maltreatmentMDD diagnosisRole of glucocorticoidsWhole blood mRNA levelsCM historyGene expressionAdrenal axisIllness exposureHealthy controlsDepressive symptomsMDD groupLarger studyMRNA expressionMRNA levelsExpression levelsInflammationTNFChildrenDiagnosisBloodAdolescentsNR3C1
2014
Exaggerating, mislabeling or simulating obsessive–compulsive symptoms: Case reports of patients claiming to have obsessive–compulsive disorder
Fontenelle L, Lins-Martins N, Melca I, Lima A, de Menezes G, Torres A, Yücel M, Miguel E, Mendlowicz M. Exaggerating, mislabeling or simulating obsessive–compulsive symptoms: Case reports of patients claiming to have obsessive–compulsive disorder. Comprehensive Psychiatry 2014, 55: 1188-1194. PMID: 24794641, DOI: 10.1016/j.comppsych.2014.03.023.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderDrug-related side effectsAxis I psychiatric disordersNon-consecutive patientsDisease courseCase reportTreatment responsePsychiatric disordersReported casesSide effectsSymptom patternsClinical judgmentOCD clinicPatientsExperienced cliniciansObsessive-compulsive symptomsPattern of responseFormal diagnosisSymptomsDiagnosisOCD diagnosisCompulsive symptomsDisordersClinicClinical vignettes
2013
2711 – Trajectory of comorbidity in obsessive-compulsive disorder
de Mathis A, Diniz J, Shavitt R, do Rosário M, Miguel E. 2711 – Trajectory of comorbidity in obsessive-compulsive disorder. European Psychiatry 2013, 28: 1. DOI: 10.1016/s0924-9338(13)77321-8.Peer-Reviewed Original ResearchComorbid psychiatric disordersFirst diagnosisPsychiatric disordersOCD patientsAnxiety disordersMain psychiatric diagnosisPost-traumatic stress disorderClinical manifestationsComorbid schizophreniaMean ageObsessive-compulsive disorderTic disordersSeparation anxiety disorderSomatoform disordersComorbid disordersPsychiatric diagnosisPanic disorderPatientsSubstance abuseSimple phobiaStress disorderHigh frequencyOCD outpatientsDiagnosisDisorders
2011
Skin picking and trichotillomania in adults with obsessive-compulsive disorder
Lovato L, Ferrão Y, Stein D, Shavitt R, Fontenelle L, Vivan A, Miguel E, Cordioli A. Skin picking and trichotillomania in adults with obsessive-compulsive disorder. Comprehensive Psychiatry 2011, 53: 562-568. PMID: 22014580, DOI: 10.1016/j.comppsych.2011.06.008.Peer-Reviewed Original ResearchConceptsPathologic skin pickingObsessive-compulsive disorderSkin pickingFourth Edition Axis IEdition Axis IStructured Clinical InterviewLogistic regression analysisComorbid body dysmorphic disorderBody dysmorphic disorderClinical characteristicsSuch comorbiditiesPrimary diagnosisAxis IClinical InterviewSpecific subgroupsMental disordersDysmorphic disorderStatistical ManualTrichotillomaniaDisordersCompulsive symptomsPatientsRegression analysisDiagnosisHigh levels
2006
Obsessive-Compulsive Spectrum Disorders and Rheumatic Fever: A Family Study
Hounie A, Pauls D, do Rosario-Campos M, Mercadante M, Diniz J, De Mathis M, De Mathis M, Chacon P, Shavitt R, Curi M, Guilherme L, Miguel E. Obsessive-Compulsive Spectrum Disorders and Rheumatic Fever: A Family Study. Biological Psychiatry 2006, 61: 266-272. PMID: 16616727, DOI: 10.1016/j.biopsych.2006.02.021.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBacterial ProteinsCase-Control StudiesChildData Interpretation, StatisticalFamilyFemaleHumansInterview, PsychologicalLogistic ModelsMaleObserver VariationObsessive-Compulsive DisorderOdds RatioPsychiatric Status Rating ScalesRheumatic FeverRiskStreptococcal InfectionsStreptolysinsConceptsFirst-degree relativesRheumatic feverObsessive-compulsive spectrum disordersSydenham's choreaFDRs of controlsStructured psychiatric interviewUnderlying etiologic mechanismsCase-control family studyFamily studiesControl first-degree relativesBest-estimate diagnosesHigh rateRF patientsCompulsive spectrum disordersOdds ratioMorbid riskEtiologic mechanismsPsychiatric interviewSpectrum disorderLogistic regressionProbandsFeverPatientsChoreaDiagnosis
2004
Transtorno de déficit de atenção/hiperatividade na infância e na adolescência: considerações clínicas e terapêuticas
Rohde L, Filho E, Benetti L, Gallois C, Kieling C. Transtorno de déficit de atenção/hiperatividade na infância e na adolescência: considerações clínicas e terapêuticas. Archives Of Clinical Psychiatry 2004, 31: 124-131. DOI: 10.1590/s0101-60832004000300002.Peer-Reviewed Original ResearchBipolar disorderAttention-deficit/hyperactivity disorderNon-systematic reviewPharmacological managementTherapeutic dilemmaDifferential diagnosisPrevalent disorderComorbid disordersClinical relevancePrecise diagnosisClinical tipsHyperactivity disorderDisordersClinical psychiatristsImpairment criteriaDiagnosisImportant impairmentComorbiditiesTreatmentAdequate useMedicationsReviewImpairment
1990
Neuropsychiatric disorders in systemic lupus erythematosus: a multidisciplinary review.
Miguel Filho E, Pereira R, de Almeida O, Hirsch R, Lafer B, Fang T, Busatto Filho G, de Arruda P. Neuropsychiatric disorders in systemic lupus erythematosus: a multidisciplinary review. Sao Paulo Medical Journal 1990, 108: 174-82. PMID: 2095621.Peer-Reviewed Original ResearchConceptsSystemic lupus erythematosusLupus erythematosusClinical featuresNeuropsychiatric alterationsPsychiatric changesChronic diseasesDifferential diagnosisPsychic symptomsNeuropsychiatric disordersPatientsDiseaseDiagnosisMultidisciplinary reviewCorticosteroidsErythematosusHypertensionUremiaPathogenesisSymptomsInfectionDepression in the elderly: a review.
de Almeida O, Lafer B, Miguel Filho E. Depression in the elderly: a review. Sao Paulo Medical Journal 1990, 108: 88-94. PMID: 2259826.Peer-Reviewed Original Research