1993
Protection against antigenically variable Borrelia burgdorferi conferred by recombinant vaccines.
Telford SR, Fikrig E, Barthold SW, Brunet LR, Spielman A, Flavell RA. Protection against antigenically variable Borrelia burgdorferi conferred by recombinant vaccines. Journal Of Experimental Medicine 1993, 178: 755-758. PMID: 8340764, PMCID: PMC2191140, DOI: 10.1084/jem.178.2.755.Peer-Reviewed Original ResearchOspA vaccination of mice with established Borrelia burgdorferi infection alters disease but not infection
Fikrig E, Barthold SW, Flavell RA. OspA vaccination of mice with established Borrelia burgdorferi infection alters disease but not infection. Infection And Immunity 1993, 61: 2553-2557. PMID: 8500891, PMCID: PMC280883, DOI: 10.1128/iai.61.6.2553-2557.1993.Peer-Reviewed Original ResearchConceptsBooster injectionComplete Freund's adjuvantVaccination of miceMurine Lyme borreliosisMurine Lyme arthritisFinal booster injectionCommencement of vaccinationNumber of miceSurface protein APostexposure immunizationOuter surface protein APostexposure vaccinationLyme arthritisFreund's adjuvantActive immunizationHeart diseaseC3H miceIncomplete adjuvantVaccinationInfectionLyme borreliosisResolution phaseMiceAdjuvantBorrelia burgdorferi
1992
Borrelia burgdorferi strain 25015: characterization of outer surface protein A and vaccination against infection.
Fikrig E, Barthold SW, Persing DH, Sun X, Kantor FS, Flavell RA. Borrelia burgdorferi strain 25015: characterization of outer surface protein A and vaccination against infection. The Journal Of Immunology 1992, 148: 2256-60. PMID: 1545130, DOI: 10.4049/jimmunol.148.7.2256.Peer-Reviewed Original ResearchConceptsSurface protein AOuter surface protein ABorrelia burgdorferi strain N40Vaccination of miceB. burgdorferiImmunized miceVaccination experimentsIntradermal challengeVaccine candidatesCerebrospinal fluidMiceProtein AStrain N40VaccinationStrain 297OspA geneBurgdorferiOspACD16NeuroborreliosisPatientsInfection