2017
Lymphedema, musculoskeletal events and arm function in older patients receiving adjuvant chemotherapy for breast cancer (Alliance A171302)
Hopkins JO, Allred J, Hurria A, Jatoi A, Lafky JM, Cohen H, Hudis C, Winer E, Mandelblatt J, Partridge A, Carey L, Muss HB. Lymphedema, musculoskeletal events and arm function in older patients receiving adjuvant chemotherapy for breast cancer (Alliance A171302). Breast Cancer Research And Treatment 2017, 166: 793-808. PMID: 28825227, PMCID: PMC5771504, DOI: 10.1007/s10549-017-4454-7.Peer-Reviewed Original ResearchConceptsQuality of lifeArm functionBreast cancerAdjuvant chemotherapyMusculoskeletal eventsPhysician-reported adverse eventsIncidence of lymphedemaAxillary node dissectionType of chemotherapyEORTC QLQ-BR23Breast cancer treatmentImpact of treatmentDetection of lymphedemaCALGB 49907Node dissectionAdverse eventsOlder patientsQLQ-BR23Standard therapyStudy entryWomen 65Month 2Elderly womenPatientsChemotherapyAxillary Management of Stage II/III Breast Cancer in Patients Treated with Neoadjuvant Systemic Therapy: Results of CALGB 40601 (HER2-Positive) and CALGB 40603 (Triple-Negative)
Ollila DW, Cirrincione CT, Berry DA, Carey LA, Sikov WM, Hudis CA, Winer EP, Golshan M. Axillary Management of Stage II/III Breast Cancer in Patients Treated with Neoadjuvant Systemic Therapy: Results of CALGB 40601 (HER2-Positive) and CALGB 40603 (Triple-Negative). Journal Of The American College Of Surgeons 2017, 224: 688-694. PMID: 28089784, PMCID: PMC5616181, DOI: 10.1016/j.jamcollsurg.2016.12.036.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAxillaBiopsyBreast NeoplasmsCarcinoma, Ductal, BreastCarcinoma, LobularFemaleHumansLymph Node ExcisionLymph NodesLymphatic MetastasisMastectomyMiddle AgedNeoadjuvant TherapyNeoplasm StagingPractice Patterns, Physicians'Receptor, ErbB-2Sentinel Lymph Node BiopsyTriple Negative Breast NeoplasmsUnited StatesConceptsAxillary lymph node dissectionNeoadjuvant systemic therapyNode-positive patientsSentinel node biopsyStage II/III breast cancerResidual axillary diseaseNode biopsyAxillary diseaseSystemic therapyBreast cancerAxillary node evaluationAxillary surgical proceduresPathologic nodal statusLymph node dissectionNode-positive diseaseCore needle biopsyFine-needle aspirationAxillary evaluationAxillary managementCALGB 40601N0 diseaseAxillary procedureNode dissectionRadiologic stagingNodal status
2015
Personalization of loco-regional care for primary breast cancer patients (part 1)
Toi M, Winer EP, Benson JR, Inamoto T, Forbes JF, von Minckwitz G, Robertson J, Grobmyer SR, Jatoi I, Sasano H, Kunkler I, Ho AY, Yamauchi C, Chow L, Huang CS, Han W, Noguchi S, Pegram MD, Yamauchi H, Lee ES, Larionov AA, Bevilacqua J, Yoshimura M, Sugie T, Yamauchi A, Krop IE, Noh DY, Klimberg VS. Personalization of loco-regional care for primary breast cancer patients (part 1). Future Oncology 2015, 11: 1297-1300. PMID: 25952777, DOI: 10.2217/fon.15.65.Peer-Reviewed Original ResearchConceptsPrimary systemic therapySystemic therapyConsensus conferenceCompletion axillary lymph node dissectionAxillary lymph node dissectionPrimary breast cancer patientsLoco-regional managementPost-Z0011 eraPreoperative hormonal therapyPrimary surgical patientsLymph node dissectionBreast cancer carePathological tumor stageBreast cancer patientsLoco-regional treatmentPrimary treatment planBreast cancer susceptibilityAxillary irradiationAxillary managementAxillary treatmentNodal depositsAxillary stagingHormonal therapyNode dissectionSentinel lymph
2011
Can Axillary Node Dissection Be Omitted in a Subset of Patients with Low Local and Regional Failure Rates?
Barkley C, Burstein H, Smith B, Bellon J, Wong J, Gadd M, Taghian A, Winer E, Iglehart JD, Harris J, Golshan M. Can Axillary Node Dissection Be Omitted in a Subset of Patients with Low Local and Regional Failure Rates? The Breast Journal 2011, 18: 23-27. PMID: 22017599, DOI: 10.1111/j.1524-4741.2011.01178.x.Peer-Reviewed Original ResearchConceptsPositive sentinel lymph nodesSentinel lymph node biopsySentinel lymph nodesAxillary node dissectionCompletion axillary node dissectionLow-risk patient populationAdjuvant treatment patternMedian patient agePercent of patientsLymph node biopsyStandard of careNodal radiationNode dissectionMicrometastatic diseaseNode biopsyLymph nodesPatient ageTreatment patternsPatient populationBreast cancerClinical dataRadiation therapyPatientsDiseaseMacrometastasis
2005
American Society of Clinical Oncology Guideline Recommendations for Sentinel Lymph Node Biopsy in Early-Stage Breast Cancer
Lyman GH, Giuliano AE, Somerfield MR, Benson AB, Bodurka DC, Burstein HJ, Cochran AJ, Cody HS, Edge SB, Galper S, Hayman JA, Kim TY, Perkins CL, Podoloff DA, Sivasubramaniam VH, Turner RR, Wahl R, Weaver DL, Wolff AC, Winer EP. American Society of Clinical Oncology Guideline Recommendations for Sentinel Lymph Node Biopsy in Early-Stage Breast Cancer. Journal Of Clinical Oncology 2005, 23: 7703-7720. PMID: 16157938, DOI: 10.1200/jco.2005.08.001.Peer-Reviewed Original ResearchConceptsAxillary lymph node dissectionEarly-stage breast cancerSentinel node biopsyCompletion axillary lymph node dissectionBreast cancerNode biopsyUse of SNBSentinel lymph node biopsyNegative axillary nodesLymph node dissectionAxillary lymph nodesLymph node biopsyStage breast cancerHealth Services CommitteeLong-term survivalAmerican SocietyUnknown clinical significanceIsolated cancer cellsAxillary metastasesNode dissectionSLN biopsyAxillary nodesSentinel lymphSLN evaluationLymph nodes
2003
Consultation with a medical oncologist before surgery and type of surgery among elderly women with early-stage breast cancer.
Keating NL, Landrum MB, Ayanian JZ, Winer EP, Guadagnoli E. Consultation with a medical oncologist before surgery and type of surgery among elderly women with early-stage breast cancer. Journal Of Clinical Oncology 2003, 21: 4532-9. PMID: 14673040, DOI: 10.1200/jco.2003.05.131.Peer-Reviewed Original ResearchConceptsBreast-conserving surgeryDefinitive surgeryMedical oncologistsType of surgeryElderly womenAxillary dissectionBreast cancerEarly-stage breast cancerGuideline-recommended careRetrospective cohort studyAxillary node dissectionBreast cancer treatmentPercent of womenPopulation-based sampleComorbid illnessesNode dissectionCohort studyGuideline recommendationsDifferentiated cancerTeaching hospitalAdjusted proportionSurgeryOncologistsCancer treatmentWomen
1999
Is axillary lymph node dissection indicated for early-stage breast cancer? A decision analysis.
Parmigiani G, Berry D, Winer E, Tebaldi C, Iglehart J, Prosnitz L. Is axillary lymph node dissection indicated for early-stage breast cancer? A decision analysis. Journal Of Clinical Oncology 1999, 17: 1465-73. PMID: 10334532, DOI: 10.1200/jco.1999.17.5.1465.Peer-Reviewed Original ResearchConceptsAxillary lymph node dissectionBenefits of ALNDLymph node dissectionQuality of lifeAdjuvant chemotherapyAdjuvant therapyNode dissectionBreast cancerLeukemia Group B StudyEarly-stage breast cancerRoutine useAxillary radiation therapyER-negative womenER-positive womenAdjuvant systemic therapySmall primary tumorsBreast-conserving therapyBreast cancer patientsEstrogen receptor statusNegative axillaOxford OverviewAdjuvant treatmentChemotherapy combinationsSurvival benefitSystemic therapy
1998
Complications of axillary lymph node dissection for carcinoma of the breast
Warmuth M, Bowen G, Prosnitz L, Chu L, Broadwater G, Peterson B, Leight G, Winer E. Complications of axillary lymph node dissection for carcinoma of the breast. Cancer 1998, 83: 1362-1368. PMID: 9762937, DOI: 10.1002/(sici)1097-0142(19981001)83:7<1362::aid-cncr13>3.0.co;2-2.Peer-Reviewed Original ResearchConceptsAxillary lymph node dissectionLymph node dissectionNode dissectionBreast carcinomaYounger ageGreater body surface areaTreatment factorsAdjuvant tamoxifen therapyEpisodes of infectionHistory of smokingLong-term complicationsMajority of symptomsFrequency of inflammationLong-term symptomsBody surface areaDaily activitiesCross-sectional surveySelf-administered questionnaireArm swellingTamoxifen therapySevere complicationsTerm complicationsYounger patientsPrimary managementRecurrence 2