2023
Post-diagnosis weight trajectories and mortality among women with breast cancer
Puklin L, Li F, Cartmel B, Zhao J, Sanft T, Lisevick A, Winer E, Lustberg M, Spiegelman D, Sharifi M, Irwin M, Ferrucci L. Post-diagnosis weight trajectories and mortality among women with breast cancer. Npj Breast Cancer 2023, 9: 98. PMID: 38042922, PMCID: PMC10693588, DOI: 10.1038/s41523-023-00603-5.Peer-Reviewed Original ResearchBody mass indexBreast cancer diagnosisWeight changeCause mortalityClinical characteristicsWeight gainWeight lossBreast cancerWeight trajectoriesPost-diagnosis weight changeBreast cancer-specific mortalityCox proportional hazards modelModern treatment eraCancer-specific mortalityCancer diagnosisModerate weight lossModerate weight gainProportional hazards modelAdverse health outcomesElectronic health recordsTreatment eraBaseline characteristicsTumor RegistryMass indexWeight managementDiet and physical activity interventions in Black and Latina women with breast cancer: A scoping review
Pichardo M, Sanft T, Ferrucci L, Romero-Ramos Y, Cartmel B, Harrigan M, Velazquez A, Fayanju O, Winer E, Irwin M. Diet and physical activity interventions in Black and Latina women with breast cancer: A scoping review. Frontiers In Oncology 2023, 13: 1079293. PMID: 36994212, PMCID: PMC10040823, DOI: 10.3389/fonc.2023.1079293.Peer-Reviewed Original ResearchBreast cancer survivorsPhysical activity interventionsLifestyle interventionCancer survivorsActivity interventionsLatina womenEfficacy trialsBreast cancerLatina breast cancer survivorsTrial of dietOne-year followFavorable behavioral changesBreast cancer diagnosisPrimary outcomeAvailable peer-reviewed literatureFuture trialsInformal care giversPilot trialSustained behavior changeEfficacy studiesHealthful lifestyleCare giversTrialsWeight lossCancer diagnosis
2021
The Breast Cancer Weight Loss trial (Alliance A011401): A description and evidence for the lifestyle intervention
Delahanty LM, Wadden TA, Goodwin PJ, Alfano CM, Thomson CA, Irwin ML, Neuhouser ML, Crane TE, Frank E, Spears PA, Gillis BP, Hershman DL, Paskett ED, Hopkins J, Bernstein V, Stearns V, White J, Hudis C, Winer EP, Carey L, Partridge AH, Ligibel JA. The Breast Cancer Weight Loss trial (Alliance A011401): A description and evidence for the lifestyle intervention. Obesity 2021, 30: 28-38. PMID: 34932888, PMCID: PMC9186690, DOI: 10.1002/oby.23287.Peer-Reviewed Original ResearchConceptsWeight loss interventionWeight loss trialLifestyle interventionHealth education materialsWeight lossLoss trialPhysical activityInvasive disease-free survivalDisease-free survivalBreast cancer patientsBreast cancer diagnosisCare of thousandsEducation materialsBaseline weightCancer outcomesCancer patientsHealth coachesCancer recurrenceBreast cancerCaloric restrictionStage IITrialsCancer diagnosisInterventionWomenCustomizing local and systemic therapies for women with early breast cancer: the St. Gallen International Consensus Guidelines for treatment of early breast cancer 2021
Burstein HJ, Curigliano G, Thürlimann B, Weber WP, Poortmans P, Regan MM, Senn HJ, Winer EP, Gnant M, Conference P, Aebi S, André F, Barrios C, Bergh J, Bonnefoi H, Morales D, Brucker S, Burstein H, Cameron D, Cardoso F, Carey L, Chua B, Ciruelos E, Colleoni M, Curigliano G, Delaloge S, Denkert C, Dubsky P, Ejlertsen B, Fitzal F, Francis P, Galimberti V, Mahmoud H, Garber J, Gnant M, Gradishar W, Gulluoglu B, Harbeck N, Huang C, Huober J, Ilbawi A, Jiang Z, Johnston S, Lee E, Loibl S, Morrow M, Partridge A, Piccart M, Poortmans P, Prat A, Regan M, Rubio I, Rugo H, Rutgers E, Sedlmayer F, Semiglazov V, Senn H, Shao Z, Spanic T, Tesarova P, Thürlimann B, Tjulandin S, Toi M, Trudeau M, Turner N, Luis I, Viale G, Watanabe T, Weber W, Winer E, Xu B. Customizing local and systemic therapies for women with early breast cancer: the St. Gallen International Consensus Guidelines for treatment of early breast cancer 2021. Annals Of Oncology 2021, 32: 1216-1235. PMID: 34242744, PMCID: PMC9906308, DOI: 10.1016/j.annonc.2021.06.023.Peer-Reviewed Original ResearchConceptsEarly-stage breast cancerBreast cancerSystemic therapyEarly breast cancerTime of diagnosisBreast cancer patientsInternational consensus guidelinesBreast cancer riskRadiation oncology providersBreast cancer diagnosisNeoadjuvant therapyMultidisciplinary careOncology providersClinical featuresConsensus guidelinesCancer patientsPatient preferencesTreatment recommendationsTreatment responseCancer riskClinical careClinical informationConsensus conferenceEarly breast cancer diagnosisPatient experience
2019
Impact of a Pre-Operative Exercise Intervention on Breast Cancer Proliferation and Gene Expression: Results from the Pre-Operative Health and Body (PreHAB) Study
Ligibel JA, Dillon D, Giobbie-Hurder A, McTiernan A, Frank E, Cornwell M, Pun M, Campbell N, Dowling RJO, Chang MC, Tolaney S, Chagpar AB, Yung RL, Freedman RA, Dominici LS, Golshan M, Rhei E, Taneja K, Huang Y, Brown M, Winer EP, Jeselsohn R, Irwin ML. Impact of a Pre-Operative Exercise Intervention on Breast Cancer Proliferation and Gene Expression: Results from the Pre-Operative Health and Body (PreHAB) Study. Clinical Cancer Research 2019, 25: 5398-5406. PMID: 31018921, DOI: 10.1158/1078-0432.ccr-18-3143.Peer-Reviewed Original ResearchConceptsPre-operative healthBreast cancerExercise interventionKi-67Exercise participantsLower cancer-specific mortalityPre-operative exercise interventionCancer-specific mortalityControl participantsBody mass indexTumor immune infiltratesImpact of exerciseBreast cancer proliferationMinutes/weekBreast cancer diagnosisOpportunity trialBaseline biopsiesImmune infiltratesMass indexSurgical excisionMean ageIntervention periodGene expressionChanges of expressionBreast tumors
2012
Body image in recently diagnosed young women with early breast cancer
Rosenberg SM, Tamimi RM, Gelber S, Ruddy KJ, Kereakoglow S, Borges VF, Come SE, Schapira L, Winer EP, Partridge AH. Body image in recently diagnosed young women with early breast cancer. Psycho-Oncology 2012, 22: 1849-1855. PMID: 23132765, PMCID: PMC3594059, DOI: 10.1002/pon.3221.Peer-Reviewed Original ResearchConceptsCancer Rehabilitation Evaluation SystemMean CARE scoreCare scoresYoung womenBreast cancerMore body image concernsBody image concernsSurgical decision-making processMusculoskeletal pain symptomsProspective cohort studyEarly breast cancerBody imageWomen age 40Impact of treatmentImage concernsRehabilitation Evaluation SystemPotential future interventionsBreast cancer diagnosisMulti-variable analysisLumpectomy groupPain symptomsRadical surgeryCohort studySurgery typePsychological factorsTime to diagnosis and breast cancer stage by race/ethnicity
Warner ET, Tamimi RM, Hughes ME, Ottesen RA, Wong YN, Edge SB, Theriault RL, Blayney DW, Niland JC, Winer EP, Weeks JC, Partridge AH. Time to diagnosis and breast cancer stage by race/ethnicity. Breast Cancer Research And Treatment 2012, 136: 813-821. PMID: 23099438, PMCID: PMC3513497, DOI: 10.1007/s10549-012-2304-1.Peer-Reviewed Original ResearchConceptsRace/ethnicityLate-stage tumorsBreast cancerMedian timeNon-Hispanic Asian/Pacific Islander womenStage III/IV breast cancerAbnormal mammogramsNational Comprehensive Cancer Network centersAsian/Pacific Islander womenBreast cancer stageNon-Hispanic blacksPacific Islander womenNon-Hispanic whitesBreast cancer diagnosisAJCC criteriaHigher proportionSymptomatic womenCancer stageStage IStage IIIInitial signsEffect of Massachusetts health insurance reform on mammography use and breast cancer stage at diagnosis
Keating NL, Kouri EM, He Y, West DW, Winer EP. Effect of Massachusetts health insurance reform on mammography use and breast cancer stage at diagnosis. Cancer 2012, 119: 250-258. PMID: 22833148, DOI: 10.1002/cncr.27757.Peer-Reviewed Original ResearchConceptsPropensity-weighted cohortsMammography ratesStage I breast cancerBehavioral Risk Factor Surveillance System surveyInsurance expansionStage I cancerI breast cancerBreast cancer stageCancer registry dataUse of mammographyRate of diagnosisRates of mammographyPropensity score analysisRates of uninsuranceHigher uninsurance ratesBreast cancer diagnosisHealth insurance expansionsI cancerCancer stageBreast cancerMammography useRegistry dataCalifornia womenMassachusetts womenDiagnosisThe Effect of Age on Delay in Diagnosis and Stage of Breast Cancer
Partridge AH, Hughes ME, Ottesen RA, Wong Y, Edge SB, Theriault RL, Blayney DW, Niland JC, Winer EP, Weeks JC, Tamimi RM. The Effect of Age on Delay in Diagnosis and Stage of Breast Cancer. The Oncologist 2012, 17: 775-782. PMID: 22554997, PMCID: PMC3380876, DOI: 10.1634/theoncologist.2011-0469.Peer-Reviewed Original ResearchConceptsHigher stage diseaseBreast cancerYoung womenStage diseaseNational Comprehensive Cancer Network centersInitial signsYounger ageHigher stageBreast cancer diagnosisAdvanced diseaseEffect of ageIndependent predictorsSymptomatic diseaseStage ICancerDiagnosisDiseaseSymptomsCancer diagnosisWomenOlder counterpartsAgeSimilar adjustmentSignsDays
2010
Physical and Psychological Outcomes Among Women in a Telephone-Based Exercise Intervention During Adjuvant Therapy for Early Stage Breast Cancer
Ligibel JA, Partridge A, Giobbie-Hurder A, Campbell N, Shockro L, Salinardi T, Winer EP. Physical and Psychological Outcomes Among Women in a Telephone-Based Exercise Intervention During Adjuvant Therapy for Early Stage Breast Cancer. Journal Of Women's Health 2010, 19: 1553-1559. PMID: 20629579, DOI: 10.1089/jwh.2009.1760.Peer-Reviewed Original ResearchConceptsEarly-stage breast cancerStage breast cancerExercise interventionBreast cancerWeight gainAdjuvant therapyHome-based exercise interventionModerate-intensity aerobic exercise interventionSingle-arm pilot studyIntensive chemotherapy regimensAerobic exercise interventionBreast cancer patientsActivity/weekBreast cancer recurrenceBreast cancer diagnosisAdjuvant chemotherapyChemotherapy regimensPostoperative complicationsSedentary womenWeek 12Cancer outcomesPoor QoLCancer patientsCardiorespiratory fitnessWeekly exercise
2009
Prevalence and Predictors of Distress in Young Women with Newly Diagnosed Early Stage Breast Cancer.
Ruddy K, Gelber S, Tamimi R, Mayer E, Schapira L, Come S, Meyer M, Winer E, Partridge A. Prevalence and Predictors of Distress in Young Women with Newly Diagnosed Early Stage Breast Cancer. Cancer Research 2009, 69: 1067-1067. DOI: 10.1158/0008-5472.sabcs-09-1067.Peer-Reviewed Original ResearchStage breast cancerBreast cancerOverall distressYoung womenHADS scoresProspective multi-center cohort studyAdvanced-stage breast cancerMulti-center cohort studyEarly-stage breast cancerMultivariate logistic regression modelBaseline surveyOnly sociodemographic factorCentral pathology reviewEarly breast cancerMultivariate logistic regressionPercent of womenCourse of careMedical history itemsLogistic regression modelsBreast cancer diagnosisEligible womenCohort studyMedian agePathology reviewHospital AnxietyInfluence of birthplace on breast cancer diagnosis and treatment for Hispanic women
Kouri EM, He Y, Winer EP, Keating NL. Influence of birthplace on breast cancer diagnosis and treatment for Hispanic women. Breast Cancer Research And Treatment 2009, 121: 743-751. PMID: 19949856, DOI: 10.1007/s10549-009-0643-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overBreast NeoplasmsCase-Control StudiesEarly DiagnosisEmigrants and ImmigrantsFemaleHealth Services AccessibilityHealth Status DisparitiesHispanic or LatinoHumansLogistic ModelsMastectomy, SegmentalMiddle AgedMultivariate AnalysisRadiotherapy, AdjuvantResidence CharacteristicsRisk FactorsUnited StatesConceptsBreast cancerHispanic womenBreast cancer diagnosisRace/ethnicityPrimary therapyWhite womenStage I breast cancerNon-Hispanic white womenCancer diagnosisEarly-stage diseaseI breast cancerInvasive breast cancerAssociation of ethnicityForeign-born HispanicsInfluence of birthplaceTherapy differsTumor characteristicsSEER areasFirst diagnosisRates of stageAdjusted ratesMultinomial logistic regressionStage IAdvanced stageAppropriate interventionsImpact of a home-based physical activity intervention upon exercise behaviors and anthropometric measures in women undergoing treatment for early stage breast cancer.
Ligibel J, Campbell N, Anita G, Shockro L, Salinardi T, Winer E. Impact of a home-based physical activity intervention upon exercise behaviors and anthropometric measures in women undergoing treatment for early stage breast cancer. Cancer Research 2009, 69: 1117. DOI: 10.1158/0008-5472.sabcs-1117.Peer-Reviewed Original ResearchEarly-stage breast cancerStage breast cancerHome-based exercise interventionBreast cancer patientsQuality of lifeBreast cancerWeight gainAdjuvant chemotherapyExercise interventionCancer patientsPhysical activityBody fatAnthropometric measuresHome-based physical activity interventionSingle-arm pilot studyWeek 12 valuesBreast cancer outcomesPhysical activity interventionsTime of enrollmentArm pilot studyBreast cancer riskImpact of exerciseLean muscle massBreast cancer diagnosisAdjuvant therapy
2008
Advances in Adjuvant Endocrine Therapy for Postmenopausal Women
Lin NU, Winer EP. Advances in Adjuvant Endocrine Therapy for Postmenopausal Women. Journal Of Clinical Oncology 2008, 26: 798-805. PMID: 18258989, DOI: 10.1200/jco.2007.15.0946.Peer-Reviewed Original ResearchConceptsPostmenopausal womenAromatase inhibitorsEndocrine therapyBreast cancerHormone receptor-positive breast cancerHormone receptor-positive cancersInitial breast cancer diagnosisReceptor-positive breast cancerMost postmenopausal womenUpfront aromatase inhibitorsYears of tamoxifenAdjuvant endocrine therapyDisease-free survivalReceptor-positive cancersCommon tumor subtypeBreast cancer diagnosisPostmenopausal settingEndocrine treatmentOverall survivalDisease recurrenceRandomized trialsAvailable trialsIndividual patientsHigh riskTumor subtypesFertility and Menopausal Outcomes in Young Breast Cancer Survivors
Partridge AH, Gelber S, Peppercorn J, Ginsburg E, Sampson E, Rosenberg R, Przypyszny M, Winer EP. Fertility and Menopausal Outcomes in Young Breast Cancer Survivors. Clinical Breast Cancer 2008, 8: 65-69. PMID: 18501060, DOI: 10.3816/cbc.2008.n.004.Peer-Reviewed Original ResearchConceptsYoung breast cancer survivorsBreast cancer survivorsCancer survivorsBreast cancerYoung womenFuture pregnanciesEarly-stage breast cancerOvarian suppression therapyBreast cancer treatmentMost young womenBreast cancer diagnosisSuppression therapyMedian timeLive birthsFertility issuesCancer treatmentDiagnosisCancer diagnosisWomenCancerSurvivorsChemotherapyPregnancyOutcomesInternational advocacy groups
2007
Genetic testing in young women with breast cancer: Results from a web-based survey
Shin J, Gelber S, Garber J, Rosenberg R, Przypyszny M, Winer E, Partridge A. Genetic testing in young women with breast cancer: Results from a web-based survey. Journal Of Clinical Oncology 2007, 25: 21093-21093. DOI: 10.1200/jco.2007.25.18_suppl.21093.Peer-Reviewed Original ResearchBreast cancerOvarian cancerFamily historyGenetic testingYoung womenWeb-based surveyYoung breast cancer survivorsTime of diagnosisBreast cancer survivorsHigh-risk populationMajority of womenFear of recurrenceQuality of lifeCross-sectional surveyLarge web-based surveyBreast cancer diagnosisCancer survivorsBRCA1/2 mutationsAge 40Baseline anxietyNumber of childrenFertility issuesCancerMultivariate modelSignificant financial relationship
2006
Factors Related to Underuse of Surveillance Mammography Among Breast Cancer Survivors
Keating NL, Landrum MB, Guadagnoli E, Winer EP, Ayanian JZ. Factors Related to Underuse of Surveillance Mammography Among Breast Cancer Survivors. Journal Of Clinical Oncology 2006, 24: 85-94. PMID: 16382117, DOI: 10.1200/jco.2005.02.4174.Peer-Reviewed Original ResearchConceptsBreast cancer survivorsSurveillance mammographyCancer survivorsMonth 7Elderly breast cancer survivorsEnd Results-Medicare dataOlder breast cancer survivorsAnnual surveillance mammographyPrimary surgical therapyRepeated-measures logistic regressionLower mammography ratesQuarter of womenPopulation-based sampleService Medicare enrolleesBreast cancer diagnosisSurgical therapyAnnual mammographyGuideline recommendationsMedical oncologistsMultivariable analysisNonclinical factorsMammography ratesBreast cancerMammography useStage I
2005
The association of ambulatory care with breast cancer stage at diagnosis among medicare beneficiaries
Keating NL, Landrum MB, Ayanian JZ, Winer EP, Guadagnoli E. The association of ambulatory care with breast cancer stage at diagnosis among medicare beneficiaries. Journal Of General Internal Medicine 2005, 20: 38-44. PMID: 15693926, PMCID: PMC1490029, DOI: 10.1111/j.1525-1497.2004.40079.x.Peer-Reviewed Original ResearchConceptsPrimary care physiciansCare physiciansBreast cancer diagnosisAdvanced cancerOutpatient careNumber of visitsMedical specialistsAdvanced stage diagnosisPreventive care visitsRetrospective cohort studyCancer diagnosisBreast cancer stagePercent of womenPopulation-based sampleCare visitsCohort studyCancer RegistryCancer stageUse of servicesElderly womenAdjusted ratesBreast cancerLower median incomeAmbulatory careHigh risk
2004
Web-Based Survey of Fertility Issues in Young Women With Breast Cancer
Partridge AH, Gelber S, Peppercorn J, Sampson E, Knudsen K, Laufer M, Rosenberg R, Przypyszny M, Rein A, Winer EP. Web-Based Survey of Fertility Issues in Young Women With Breast Cancer. Journal Of Clinical Oncology 2004, 22: 4174-4183. PMID: 15483028, DOI: 10.1200/jco.2004.01.159.Peer-Reviewed Original ResearchConceptsPercent of womenBreast cancerYoung womenFertility issuesEarly-stage breast cancerYoung breast cancer survivorsYear of diagnosisBreast cancer survivorsMultivariate logistic regressionE-mail remindersBreast cancer diagnosisPrior pregnancyYounger patientsCancer survivorsFertility concernsTreatment decisionsWeb-based surveyEligible respondentsInfertility concernsLogistic regressionCancerDiagnosisCancer diagnosisWomenMore children