2014
Optimizing linkage and retention to hypertension care in rural Kenya (LARK hypertension study): study protocol for a randomized controlled trial
Vedanthan R, Kamano JH, Naanyu V, Delong AK, Were MC, Finkelstein EA, Menya D, Akwanalo CO, Bloomfield GS, Binanay CA, Velazquez EJ, Hogan JW, Horowitz CR, Inui TS, Kimaiyo S, Fuster V. Optimizing linkage and retention to hypertension care in rural Kenya (LARK hypertension study): study protocol for a randomized controlled trial. Trials 2014, 15: 143. PMID: 24767476, PMCID: PMC4113229, DOI: 10.1186/1745-6215-15-143.Peer-Reviewed Original ResearchMeSH KeywordsBlack PeopleBlood PressureCell PhoneClinical ProtocolsCommunicationCommunity Health ServicesCommunity Health WorkersCost-Benefit AnalysisHealth BehaviorHealth Care CostsHealth Knowledge, Attitudes, PracticeHumansHypertensionKenyaMotivational InterviewingPatient CompliancePatientsProfessional-Patient RelationsResearch DesignRural Health ServicesTime FactorsTreatment OutcomeConceptsCommunity health workersHypertension careBlood pressureHealth workersHypertensive individualsMethods/designThis studyCo-primary outcome measuresNon-communicable disease managementHypertension care programDisability-adjusted life yearsSystolic blood pressureOne-year changeHealth Belief ModelCost-effectiveness analysisUsual careMiddle-income countriesHypertension managementHypertension treatmentControl rateRisk factorsOutcome measuresDesignThis studyBehavioral communication strategyCare programLife years
2010
Departures from the protocol during conduct of a clinical trial: a pattern from the data record consistent with a learning curve
Taekman J, Stafford-Smith M, Velazquez E, Wright M, Phillips-Bute B, Pfeffer M, Sellers M, Pieper K, Newman M, Van de Werf F, Diaz R, Leimberger J, Califf R. Departures from the protocol during conduct of a clinical trial: a pattern from the data record consistent with a learning curve. BMJ Quality & Safety 2010, 19: 405. PMID: 20702441, PMCID: PMC3258507, DOI: 10.1136/qshc.2008.028605.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionMyocardial infarctionClinical trial researchLearning curvePatient rankMulticentre trialSlow enrollmentAcademic research organizationsPatient deathClinical trialsPatientsTrial conductTrial researchClinical researchPatient safetyPatient ordersTrialsInfarctionValsartanFirst yearDeathRecruitment ratesSimilar patternStart dateSafety