Utility of 3-dimensional echocardiography, global longitudinal strain, and exercise stress echocardiography to detect cardiac dysfunction in breast cancer patients treated with doxorubicin-containing adjuvant therapy
Khouri MG, Hornsby WE, Risum N, Velazquez EJ, Thomas S, Lane A, Scott JM, Koelwyn GJ, Herndon JE, Mackey JR, Douglas PS, Jones LW. Utility of 3-dimensional echocardiography, global longitudinal strain, and exercise stress echocardiography to detect cardiac dysfunction in breast cancer patients treated with doxorubicin-containing adjuvant therapy. Breast Cancer Research And Treatment 2014, 143: 531-539. PMID: 24390149, PMCID: PMC4521213, DOI: 10.1007/s10549-013-2818-1.Peer-Reviewed Original ResearchMeSH KeywordsAdultBreast NeoplasmsDoxorubicinEchocardiography, StressExercise TestFemaleHeart DiseasesHumansMiddle AgedConceptsGlobal longitudinal strainBreast cancer patientsSubclinical cardiac dysfunctionCardiac dysfunctionCancer patientsCardiac indexStress echocardiographyEarly breast cancer patientsLongitudinal strainVentricular ejection fraction assessmentLeft ventricular ejection fraction assessmentAdult oncology settingsPost-exercise increaseEarly breast cancerLeft ventricular functionSex-matched controlsSpeckle tracking echocardiographyEjection fraction assessmentSimilar LVEFAdjuvant therapyEchocardiographic parametersCardiopulmonary exerciseAsymptomatic womenVentricular functionCardiopulmonary function