2017
Mental stress-induced left ventricular dysfunction and adverse outcome in ischemic heart disease patients
Sun JL, Boyle SH, Samad Z, Babyak MA, Wilson JL, Kuhn C, Becker RC, Ortel TL, Williams RB, Rogers JG, O’Connor C, Velazquez EJ, Jiang W. Mental stress-induced left ventricular dysfunction and adverse outcome in ischemic heart disease patients. European Journal Of Preventive Cardiology 2017, 24: 591-599. PMID: 28067532, PMCID: PMC6093615, DOI: 10.1177/2047487316686435.Peer-Reviewed Original ResearchMeSH KeywordsAgedCitalopramDisease-Free SurvivalFemaleHumansMaleMental HealthMiddle AgedMultivariate AnalysisMyocardial IschemiaProportional Hazards ModelsRisk AssessmentRisk FactorsSelective Serotonin Reuptake InhibitorsStress, PsychologicalStroke VolumeTime FactorsTreatment OutcomeVentricular Dysfunction, LeftVentricular Function, LeftConceptsMental stress-induced myocardial ischemiaMajor adverse cardiovascular eventsAdverse cardiovascular eventsLeft ventricular ejection fraction changeVentricular ejection fraction changeStable ischemic heart diseaseIschemic heart disease patientsLeft ventricular ejection fractionStress-induced myocardial ischemiaEjection fraction changesVentricular ejection fractionIschemic heart diseaseCardiovascular eventsHeart disease patientsMyocardial ischemiaEjection fractionStudy endpointDisease patientsHeart diseaseMental Stress–Induced Myocardial IschemiaStress-induced left ventricular dysfunctionFuture adverse cardiovascular eventsLeft ventricular dysfunctionHeart failure statusAssociation of indices
2016
Associations between positive emotional well-being and stress-induced myocardial ischemia Well-being scores predict exercise-induced ischemia
Feigal JP, Boyle SH, Samad Z, Velazquez EJ, Wilson JL, Becker RC, Williams RB, Kuhn CM, Ortel TL, Rogers JG, O'Connor CM, Jiang W. Associations between positive emotional well-being and stress-induced myocardial ischemia Well-being scores predict exercise-induced ischemia. Journal Of Psychosomatic Research 2016, 93: 14-18. PMID: 28107887, PMCID: PMC6044283, DOI: 10.1016/j.jpsychores.2016.11.012.Peer-Reviewed Original ResearchConceptsLeft ventricular ejection fractionHealth-related behaviorsMyocardial ischemiaStable ischemic heart disease patientsIschemic heart disease patientsWall motion score indexExercise-induced ischemiaTreadmill exercise testingEpidemiologic Studies Depression ScaleStress-induced ischemiaInverse correlationHeart disease patientsSignificant inverse correlationInducible ischemiaAdult patientsExercise testingIschemic responseEjection fractionDisease patientsTreatment trialsSimilar inverse correlationDepression ScaleExercise stressDepressive symptomsUnderscore areas
2014
Metabolomics analysis reveals insights into biochemical mechanisms of mental stress-induced left ventricular dysfunction
Boyle SH, Matson WR, Velazquez EJ, Samad Z, Williams RB, Sharma S, Thomas B, Wilson JL, O’Connor C, Jiang W. Metabolomics analysis reveals insights into biochemical mechanisms of mental stress-induced left ventricular dysfunction. Metabolomics 2014, 11: 571-582. PMID: 25983674, PMCID: PMC4431771, DOI: 10.1007/s11306-014-0718-y.Peer-Reviewed Original ResearchLeft ventricular dysfunctionLeft ventricular ejection fractionMental stress-induced myocardial ischemiaStress-induced left ventricular dysfunctionNormal left ventricular responseStress-induced myocardial ischemiaCoronary heart disease patientsLeft ventricular responseVentricular ejection fractionAdult CHD patientsHeart disease patientsConventional risk indicatorsVentricular dysfunctionAdverse eventsEjection fractionStable CHDVentricular responseCHD patientsDisease patientsMyocardial ischemiaLVD groupCardiovascular conditionsMental stressorsPatientsGreater risk