2018
The “mortality ascent”
Herrera-Escobar JP, Rios-Diaz AJ, Zogg CK, Wolf LL, Harlow A, Schneider EB, Cooper Z, Ordonez CA, Salim A, Haider AH. The “mortality ascent”. Journal Of Trauma And Acute Care Surgery 2018, 84: 139-145. PMID: 28930947, DOI: 10.1097/ta.0000000000001706.Peer-Reviewed Original ResearchConceptsUnstable trauma patientsLevel I TCsLevel II TCsHours postadmissionTrauma patientsLevel ILevel IIMortality riskHospital mortalityLog-binomial regression modelsNational Trauma Data BankComparable mortality riskHospital-level confoundersInjury Severity ScoreSystolic blood pressureAvailable treatment modalitiesTrauma Data BankSpecific risk factorsRisk-adjusted modelsBlood pressureHigher relative mortalityUnstable patientsBurn patientsSeverity scoreTreatment modalities
2017
Impact of Surgeon Specialty on Perioperative Outcomes of Surgery for Benign Esophageal Diseases: A NSQIP Analysis
Khoshhal Z, Canner J, Schneider E, Stem M, Haut E, Schlottmann F, Barbetta A, Mungo B, Lidor A, Molena D. Impact of Surgeon Specialty on Perioperative Outcomes of Surgery for Benign Esophageal Diseases: A NSQIP Analysis. Journal Of Laparoendoscopic & Advanced Surgical Techniques 2017, 27: 924-930. PMID: 28594583, PMCID: PMC5749579, DOI: 10.1089/lap.2017.0083.Peer-Reviewed Original ResearchConceptsBenign esophageal diseaseGeneral surgeonsHeller esophagomyotomyEsophageal diseaseGS groupPerioperative outcomesHome dischargePEH repairSurgeon specialtyBetter outcomesMore home dischargesMultivariable logistic regressionParaesophageal hernia repairLower mortality rateNSQIP AnalysisHospital lengthOverall morbidityDischarge destinationGastric fundoplicationReadmission ratesLaparoscopic approachLow comorbidityShorter LOSACS-NSQIPBenign disease
2016
Race-based differences in duration of stay among universally insured coronary artery bypass graft patients in military versus civilian hospitals
Chowdhury R, Davis WA, Chaudhary MA, Jiang W, Zogg CK, Schoenfeld AJ, Jaklitsch MT, Kaneko T, Learn PA, Haider AH, Schneider EB. Race-based differences in duration of stay among universally insured coronary artery bypass graft patients in military versus civilian hospitals. Surgery 2016, 161: 1090-1099. PMID: 27932028, DOI: 10.1016/j.surg.2016.10.022.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBlack or African AmericanCohort StudiesConfidence IntervalsCoronary Artery BypassCoronary Artery DiseaseDatabases, FactualFemaleHealthcare DisparitiesHospital MortalityHospitals, MilitaryHospitals, PublicHumansLength of StayMaleMiddle AgedPrognosisRegression AnalysisRisk AssessmentSurvival AnalysisTreatment OutcomeUnited StatesUniversal Health InsuranceWhite PeopleConceptsCoronary artery bypass graftArtery bypass graftCoronary artery bypass graft patientsDuration of stayBypass graft patientsBypass graftRace-based differencesGraft patientsBlack patientsMilitary HospitalCivilian hospitalsHospital-level factorsEligible patientsWhite patientsMale patientsCivilian facilitiesWhite racePatientsStayTRICARE coverageNegative binomial regressionHospitalApparent mitigationGraftGreater durationValidation of international trauma scoring systems in urban trauma centres in India
Roy N, Gerdin M, Schneider E, Veetil D, Khajanchi M, Kumar V, Saha M, Dharap S, Gupta A, Tomson G, von Schreeb J. Validation of international trauma scoring systems in urban trauma centres in India. Injury 2016, 47: 2459-2464. PMID: 27667119, DOI: 10.1016/j.injury.2016.09.027.Peer-Reviewed Original ResearchConceptsInjury Severity ScoreTrauma Injury Severity ScoreKampala Trauma ScoreTrauma patientsCasualty departmentPhysiological scoreTrauma centerSeverity scoreProspective multi-centre observational cohort studyMulti-center observational cohort studyInjury Severity Scale scoreAdult trauma patientsObservational cohort studySeverity Scale scoreUrban trauma centerHistory of injuryIncome country settingsMiddle-income country settingsHospital mortalityLate mortalityUrban Indian settingAdult patientsCohort studyInpatient mortalityPhysiologic scorePredictors of emergency ventral hernia repair: Targets to improve patient access and guide patient selection for elective repair
Wolf LL, Scott JW, Zogg CK, Havens JM, Schneider EB, Smink DS, Salim A, Haider AH. Predictors of emergency ventral hernia repair: Targets to improve patient access and guide patient selection for elective repair. Surgery 2016, 160: 1379-1391. PMID: 27542434, DOI: 10.1016/j.surg.2016.06.027.Peer-Reviewed Original ResearchMeSH KeywordsAdultAge FactorsAgedAged, 80 and overConfidence IntervalsDatabases, FactualElective Surgical ProceduresEmergenciesFemaleFollow-Up StudiesHealth Services AccessibilityHernia, VentralHerniorrhaphyHospital MortalityHumansInsurance CoverageLogistic ModelsMaleMiddle AgedOdds RatioPatient SelectionPredictive Value of TestsQuality ImprovementRetrospective StudiesRisk AssessmentSeverity of Illness IndexSex FactorsTime FactorsTreatment OutcomeConceptsVentral hernia repairEmergency ventral hernia repairHospital-level factorsHernia repairIndependent predictorsPatient selectionElective operationsWorse outcomesEmergency repairLonger hospital stayNationwide Inpatient SampleMultivariable logistic regressionUnited States populationRace/ethnicityHospital deathHospital staySecondary outcomesElective repairPrimary outcomePayer statusInpatient SamplePatient outcomesVentral herniasElective careGreater oddsOutcomes of abdominoperineal resection for management of anal cancer in HIV-positive patients: a national case review
Leeds IL, Alturki H, Canner JK, Schneider EB, Efron JE, Wick EC, Gearhart SL, Safar B, Fang SH. Outcomes of abdominoperineal resection for management of anal cancer in HIV-positive patients: a national case review. World Journal Of Surgical Oncology 2016, 14: 208. PMID: 27495294, PMCID: PMC4974747, DOI: 10.1186/s12957-016-0970-x.Peer-Reviewed Original ResearchMeSH KeywordsAbdomenAdultAge FactorsAgedAnus NeoplasmsCarcinoma, Squamous CellComorbidityFemaleFollow-Up StudiesHealth Status DisparitiesHIV InfectionsHospital MortalityHumansIncidenceLength of StayMaleMiddle AgedNeoplasm Recurrence, LocalPerineumPostoperative ComplicationsRetrospective StudiesRisk FactorsSalvage TherapyTreatment OutcomeConceptsHIV-positive patientsLength of stayHIV-negative patientsAnal cancerNational Inpatient SampleAbdominoperineal resectionHospitalization costsHIV infectionAnal squamous cell cancerAnal squamous cell carcinomaUtilization Project National Inpatient SampleGreater hospitalization costsWorse postoperative recoveryHIV-positive groupMethodsA retrospective reviewAnal cancer patientsSquamous cell cancerHuman immunodeficiency virusMultivariable logistic regressionSquamous cell carcinomaHospital mortalityHospital stayPerioperative complicationsPostoperative hemorrhagePostoperative outcomesIntensity of treatment, end-of-life care, and mortality for older patients with severe traumatic brain injury
Lilley E, Williams K, Schneider E, Hammouda K, Salim A, Haider A, Cooper Z. Intensity of treatment, end-of-life care, and mortality for older patients with severe traumatic brain injury. Journal Of Trauma And Acute Care Surgery 2016, 80: 998-1004. PMID: 26953761, DOI: 10.1097/ta.0000000000001028.Peer-Reviewed Original ResearchConceptsSevere traumatic brain injuryTraumatic brain injuryGeriatric patientsFunctional statusBrain injuryHospital mortality outcomesPatients 65 yearsDays of injuryGoals of careFurther aggressive treatmentSurgery of TraumaIntensity of treatmentHospital mortalityHospital deathLife decision makingAggressive treatmentHospital dischargeIdentifies patientsNeurologic statusNonresponder groupOlder patientsRetrospective reviewMortality outcomesPoor prognosisFunctional impairment30‐Day In‐hospital Trauma Mortality in Four Urban University Hospitals Using an Indian Trauma Registry
Roy N, Gerdin M, Ghosh S, Gupta A, Kumar V, Khajanchi M, Schneider E, Gruen R, Tomson G, von Schreeb J. 30‐Day In‐hospital Trauma Mortality in Four Urban University Hospitals Using an Indian Trauma Registry. World Journal Of Surgery 2016, 40: 1299-1307. PMID: 26911610, DOI: 10.1007/s00268-016-3452-y.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBlood PressureChildChild, PreschoolDeveloping CountriesFemaleGlasgow Coma ScaleHospital MortalityHospitalizationHospitals, PublicHospitals, UniversityHospitals, UrbanHumansIndiaInfantMaleMiddle AgedProspective StudiesRegistriesTime-to-TreatmentWounds and InjuriesYoung AdultConceptsHospital trauma mortalityTrauma mortalityUniversity HospitalTrauma systemMortality rateAdmission systolic blood pressureHospital mortality rateDays of hospitalizationGlasgow Coma ScoreSystolic blood pressureUrban university hospitalTrauma mortality ratesPublic university hospitalPhysiological scoringCare delaysLate mortalityComa ScoreBlood pressureMedian ageTrauma patientsTrauma registryAdmission vitalsTrauma careTraumatic injuryHigh-income countries“Halo effect” in trauma centers: does it extend to emergent colectomy?
Nagarajan N, Selvarajah S, Gani F, Alshaikh HN, Giuliano K, Zogg CK, Schneider EB, Haider AH. “Halo effect” in trauma centers: does it extend to emergent colectomy? Journal Of Surgical Research 2016, 203: 231-237. PMID: 27125867, DOI: 10.1016/j.jss.2016.01.037.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overColectomyDatabases, FactualDiverticulitis, ColonicEmergenciesFemaleHospital ChargesHospital MortalityHumansLength of StayLinear ModelsLogistic ModelsMaleMiddle AgedPoisson DistributionQuality Assurance, Health CareQuality Indicators, Health CareTrauma CentersTreatment OutcomeUnited StatesYoung AdultConceptsLength of stayNontrauma centersHospital-level characteristicsTrauma centerEmergent colectomyEmergency general surgery conditionsEmergency general surgery proceduresNationwide Emergency Department SampleEmergency surgical interventionOdds of mortalityEmergency Department SampleGeneral surgery proceduresNontrauma conditionsHospital mortalityMedian ageSurgical interventionSurgical conditionsImproved outcomesSex distributionSurgical careMedian chargePatientsSurgery proceduresSurgery conditionsCase mix
2015
United States trends in thrombolysis for older adults with acute ischemic stroke
George B, Asemota A, Dorsey E, Haider A, Smart B, Urrutia V, Schneider E. United States trends in thrombolysis for older adults with acute ischemic stroke. Clinical Neurology And Neurosurgery 2015, 139: 16-23. PMID: 26363362, DOI: 10.1016/j.clineuro.2015.08.031.Peer-Reviewed Original ResearchConceptsNationwide Inpatient SampleAcute ischemic strokeIschemic strokeOlder adultsStudy periodHospital mortality rateAdult stroke patientsHigh-volume hospitalsLength of stayRate of thrombolysisHigh-volume facilitiesPopulation-based ratesCochran-Armitage testThrombolysis groupVolume hospitalsUrban patientsThrombolysis useIntracerebral hemorrhageStroke patientsPrimary diagnosisInpatient SampleOdds ratioHospitalization dataThrombolysisAge subgroupsOutcomes of trauma care at centers treating a higher proportion of older patients
Zafar S, Obirieze A, Schneider E, Hashmi Z, Scott V, Greene W, Efron D, MacKenzie E, Cornwell E, Haider A. Outcomes of trauma care at centers treating a higher proportion of older patients. Journal Of Trauma And Acute Care Surgery 2015, 78: 852-859. PMID: 25742246, DOI: 10.1097/ta.0000000000000557.Peer-Reviewed Original ResearchConceptsOlder trauma patientsOlder patientsTrauma patientsTrauma centerLevel 2 trauma centerMultivariate logistic regression modelRisk-adjusted mortality ratioYoung adultsGeriatric trauma patientsAdult trauma patientsBurden of injuryLength of stayObserved-expected ratioTrauma center performanceHigher proportionLogistic regression modelsGeriatric traumaYounger patientsTrauma deathsMortality ratioTrauma visitsTrauma careEpidemiologic studiesPatientsBetter outcomesNational estimates of predictors of outcomes for emergency general surgery
Shah AA, Haider AH, Zogg CK, Schwartz DA, Haut ER, Zafar SN, Schneider EB, Velopulos CG, Shafi S, Zafar H, Efron DT. National estimates of predictors of outcomes for emergency general surgery. Journal Of Trauma And Acute Care Surgery 2015, 78: 482-491. PMID: 25710417, DOI: 10.1097/ta.0000000000000555.Peer-Reviewed Original ResearchConceptsEmergency general surgeryEGS patientsMajor complicationsGeneral surgeryMultivariate logistic regression analysisOverall complication ratePredictors of mortalityClinical Modification codesOverall mortality rateNationwide Inpatient SampleSeparate multivariate logistic regression analysesSurgery of TraumaDRG International ClassificationLogistic regression analysisHighest income quartileHospital complicationsHospital mortalityComplication ratePatient demographicsSurgical complicationsIndependent predictorsPrimary outcomeEGS conditionsMean ageInpatient SampleTraumatic brain injury in the elderly: morbidity and mortality trends and risk factors
Haring R, Narang K, Canner J, Asemota A, George B, Selvarajah S, Haider A, Schneider E. Traumatic brain injury in the elderly: morbidity and mortality trends and risk factors. Journal Of Surgical Research 2015, 195: 1-9. PMID: 25724764, DOI: 10.1016/j.jss.2015.01.017.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overBrain InjuriesFemaleHospital MortalityHospitalizationHumansMaleRetrospective StudiesRisk FactorsUnited StatesConceptsTraumatic brain injuryMechanism of injuryBrain injuryTBI-related deathsTBI-related hospitalizationOdds of deathMultivariable logistic regressionNationwide Inpatient SampleLogistic regression analysisOlder age groupsMore comorbiditiesMale patientsPayer statusTBI patientsInpatient SampleRisk factorsHigher oddsInjury severityPatientsMortality trendsAge groupsInjuryLogistic regressionTBI dataComorbiditiesOutcomes after emergency general surgery at teaching versus nonteaching hospitals
Zafar S, Shah A, Hashmi Z, Efron D, Haut E, Schneider E, Schwartz D, Velopulos C, Cornwell E, Haider A. Outcomes after emergency general surgery at teaching versus nonteaching hospitals. Journal Of Trauma And Acute Care Surgery 2015, 78: 69-77. PMID: 25539205, DOI: 10.1097/ta.0000000000000493.Peer-Reviewed Original ResearchMeSH KeywordsAcute DiseaseAdolescentAdultAgedAged, 80 and overComorbidityEmergency TreatmentFemaleGeneral SurgeryHospital CostsHospital MortalityHospitals, TeachingHumansLength of StayMaleMiddle AgedOutcome and Process Assessment, Health CarePostoperative ComplicationsPropensity ScoreQuality of Health CareRetrospective StudiesSeverity of Illness IndexUnited StatesConceptsLength of stayHospital costsMajor complicationsQuality of careTeaching hospitalEGS conditionsNonteaching hospitalsEmergency general surgery conditionsEffect estimatesEmergency general surgeryHospital-level factorsMajority of patientsNationwide Inpatient SampleHigher hospital costsSurgery of TraumaEmergency surgical conditionsStandardized differenceMultivariate regression analysisEGS volumeHospital mortalityOperative managementInpatient SampleSurgical conditionsWorse outcomesGeneral surgery
2014
Hospital Volume and Patient Outcomes in Hepato-Pancreatico-Biliary Surgery: Is Assessing Differences in Mortality Enough?
Schneider EB, Ejaz A, Spolverato G, Hirose K, Makary MA, Wolfgang CL, Ahuja N, Weiss M, Pawlik TM. Hospital Volume and Patient Outcomes in Hepato-Pancreatico-Biliary Surgery: Is Assessing Differences in Mortality Enough? Journal Of Gastrointestinal Surgery 2014, 18: 2105-2115. PMID: 25297443, DOI: 10.1007/s11605-014-2619-9.Peer-Reviewed Original ResearchConceptsLength of stayHV hospitalsHV centersHospital volumeMajor complicationsLV centersBiliary surgeryHPB surgeryHospital patientsShorter median LOSMedian LOSComplex HPB surgeryHospital volume strataIncidence of complicationsPost-operative complicationsOverall mean ageHepato-PancreaticoLV hospitalsMedical comorbiditiesImpact of regionalizationMean ageBiliary proceduresHemorrhagic anemiaPatient outcomesIndex mortalityEncephalitis Hospitalization Rates and Inpatient Mortality in the United States, 2000-2010
George B, Schneider E, Venkatesan A. Encephalitis Hospitalization Rates and Inpatient Mortality in the United States, 2000-2010. PLOS ONE 2014, 9: e104169. PMID: 25192177, PMCID: PMC4156306, DOI: 10.1371/journal.pone.0104169.Peer-Reviewed Original ResearchConceptsNationwide Inpatient SampleHospitalization ratesEncephalitis hospitalizationsInpatient mortalitySpecified causeComorbid HIV/AIDSAcute phase outcomesComorbid HIV infectionDiagnosis of encephalitisOdds of mortalityRetrospective observational studyCommon infectious agentsAcute care hospitalsYears of ageHerpes simplex virusHIV/AIDSAutoimmune conditionsCare hospitalHIV infectionWest Nile virusCause-specific ratesEncephalitis patientsViral causeAdjusted oddsInpatient SampleAssociation Between Race and Age in Survival After Trauma
Hicks C, Hashmi Z, Velopulos C, Efron D, Schneider E, Haut E, Cornwell E, Haider A. Association Between Race and Age in Survival After Trauma. JAMA Surgery 2014, 149: 642-647. PMID: 24871941, PMCID: PMC5995325, DOI: 10.1001/jamasurg.2014.166.Peer-Reviewed Original ResearchConceptsCharlson Comorbidity IndexPatients 65 yearsOlder patientsBlack patientsInjury severityComorbidity indexRacial disparitiesWhite patientsOdds ratioBetter outcomesCharlson Comorbidity Index scoreClinical Modification diagnosis codesLogistic regressionComorbidity Index scoreOlder black patientsOlder white patientsYoung black patientsYoung white patientsMost older patientsIntent of injuryNationwide Inpatient SampleMultivariable logistic regressionUnadjusted odds ratioUnivariable logistic regressionHead injury severityRace-based differences in length of stay among patients undergoing pancreatoduodenectomy
Schneider EB, Calkins KL, Weiss MJ, Herman JM, Wolfgang CL, Makary MA, Ahuja N, Haider AH, Pawlik TM. Race-based differences in length of stay among patients undergoing pancreatoduodenectomy. Surgery 2014, 156: 528-537. PMID: 24973128, DOI: 10.1016/j.surg.2014.04.004.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlack or African AmericanCross-Sectional StudiesFemaleGeneral SurgeryHealthcare DisparitiesHispanic or LatinoHospital MortalityHospitalsHumansLength of StayLogistic ModelsMaleMiddle AgedPancreaticoduodenectomyPostoperative ComplicationsRacial GroupsRetrospective StudiesUnited StatesWhite PeopleConceptsHigh-volume hospitalsHigh-volume surgeonsHispanic patientsRace-based differencesWhite patientsMedian annual surgeon volumeAnnual hospital volumeAnnual surgeon volumeOverall median LOSNationwide Inpatient SampleMultivariable logistic regressionLength of stayHospital mortalityHospital lengthMedian LOSHospital volumeOperative morbidityProvider volumeSurgeon volumeMedian lengthPD patientsInpatient SamplePatient racePancreatoduodenectomyEligible individualsIncreased mortality associated with EMS transport of gunshot wound victims when compared to private vehicle transport
Zafar S, Haider A, Stevens K, Ray-Mazumder N, Kisat M, Schneider E, Chi A, Galvagno S, Cornwell E, Efron D, Haut E. Increased mortality associated with EMS transport of gunshot wound victims when compared to private vehicle transport. Injury 2014, 45: 1320-1326. PMID: 24957424, DOI: 10.1016/j.injury.2014.05.032.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAmbulancesAutomobilesEmergency Medical ServicesFemaleFluid TherapyGravity SuitsHospital MortalityHumansImmobilizationInjury Severity ScoreIntubation, IntratrachealMaleMiddle AgedMonitoring, PhysiologicOutcome and Process Assessment, Health CareRetrospective StudiesTime FactorsTransportation of PatientsTrauma CentersUnited StatesWounds, GunshotConceptsEmergency medical servicesProportion of patientsGSW patientsTrauma centerGunshot woundsNational Trauma Data BankGunshot wound victimsTrauma Data BankIndividual trauma centersMultivariable regression analysisHospital mortalityPatient demographicsUnadjusted mortalityTrauma patientsMultivariable analysisTwofold oddsEMS transportMortality differencesPatientsInjury severityPrivate vehicle transportMortalityWide variationMedical servicesFurther studiesBenchmarking of Trauma Care Worldwide: The Potential Value of an International Trauma Data Bank (ITDB)
Haider A, Hashmi Z, Gupta S, Zafar S, David J, Efron D, Stevens K, Zafar H, Schneider E, Voiglio E, Coimbra R, Haut E. Benchmarking of Trauma Care Worldwide: The Potential Value of an International Trauma Data Bank (ITDB). World Journal Of Surgery 2014, 38: 1882-1891. PMID: 24817407, DOI: 10.1007/s00268-014-2629-5.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overBenchmarkingDatabases, FactualDeveloped CountriesDeveloping CountriesFeasibility StudiesFemaleFranceGlobal HealthHospital MortalityHumansLogistic ModelsMaleMiddle AgedPakistanRegistriesTrauma CentersWounds, NonpenetratingWounds, PenetratingYoung AdultConceptsTrauma Data BankTrauma mortalityTrauma centerMortality ratioTrauma outcomesNational Trauma Data BankTrauma dataE mortality ratioNational Trauma RegistryMultivariable logistic regressionBlunt/Worse survivalTrauma registrySubset analysisPatient outcomesTrauma carePatientsLMIC centerLogistic regressionKey covariatesOutcomesInjuryMortalityPredictorsSimilar results