2020
Incidence and clinical outcomes of bleeding complications and acute limb ischemia in STEMI and cardiogenic shock
Pahuja M, Ranka S, Chehab O, Mishra T, Akintoye E, Adegbala O, Yassin A, Ando T, Thayer K, Shah P, Kimmelstiel C, Salehi P, Kapur N. Incidence and clinical outcomes of bleeding complications and acute limb ischemia in STEMI and cardiogenic shock. Catheterization And Cardiovascular Interventions 2020, 97: 1129-1138. PMID: 32473083, PMCID: PMC8344361, DOI: 10.1002/ccd.29003.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionAcute limb ischemiaLength of stayCardiogenic shockCS-STEMIHospital mortalityVascular complicationsLimb ischemiaClinical outcomesManagement of CSPercutaneous ventricular assist deviceIntra-aortic balloon pumpPercutaneous mechanical circulatory supportRetrospective cohort studyElevation myocardial infarctionMechanical circulatory supportVentricular assist deviceU.S. national databaseTandem HeartMultiorgan failureCohort studyBalloon pumpCommon complicationMembrane oxygenationCirculatory support
2019
Palliative care referral in ST-segment elevation myocardial infarction complicated with cardiogenic shock in the United States
Ando T, Akintoye E, Uemura T, Adegbala O, Ashraf S, Pahuja M, Shokr M, Takagi H, Grines C, Afonso L, Briasoulis A. Palliative care referral in ST-segment elevation myocardial infarction complicated with cardiogenic shock in the United States. Heart & Lung 2019, 49: 25-29. PMID: 31703953, DOI: 10.1016/j.hrtlng.2019.10.005.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionPalliative care referralElevation myocardial infarctionPC referralSTEMI-CSCardiogenic shockCare referralMyocardial infarctionMechanical circulatory support useCoronary artery bypass graftStudy periodPC referral rateArtery bypass graftExtended care facilitiesNationwide Inpatient SampleEdition Clinical ModificationTrends of utilizationLow-income statusPC encountersPC consultationBypass graftMultivariable analysisInpatient SampleReferral ratesHigh comorbidityIn-Hospital Outcomes of ST-Segment Elevation Myocardial Infarction Complicated With Cardiogenic Shock at Safety-Net Hospitals in the United States (from the Nationwide Inpatient Sample)
Ando T, Akintoye E, Adegbala O, Ashraf S, Shokr M, Takagi H, Grines C, Afonso L, Briasoulis A. In-Hospital Outcomes of ST-Segment Elevation Myocardial Infarction Complicated With Cardiogenic Shock at Safety-Net Hospitals in the United States (from the Nationwide Inpatient Sample). The American Journal Of Cardiology 2019, 124: 485-490. PMID: 31213279, DOI: 10.1016/j.amjcard.2019.05.037.Peer-Reviewed Original ResearchMeSH KeywordsAge DistributionAgedAged, 80 and overArrhythmias, CardiacAssisted CirculationCoronary Artery BypassDatabases, FactualEthnicityFemaleHeart-Assist DevicesHospital MortalityHumansMaleMiddle AgedPercutaneous Coronary InterventionRenal DialysisSafety-net ProvidersShock, CardiogenicST Elevation Myocardial InfarctionStrokeThrombolytic TherapyUnited StatesConceptsSafety-net hospitalPercutaneous coronary interventionSTEMI-CSCardiogenic shockHospital mortalityCoronary interventionST-Segment Elevation Myocardial Infarction ComplicatedST-segment elevation myocardial infarctionAdministration of thrombolysisMyocardial Infarction ComplicatedCoronary artery bypassElevation myocardial infarctionMechanical circulatory supportNationwide Inpatient SampleNew dialysisArtery bypassHospital outcomesClinical outcomesCirculatory supportInpatient stayMedian lengthPoor outcomeFatal arrhythmiasInpatient SampleMyocardial infarctionTrends in the Incidence of In-Hospital Mortality, Cardiogenic Shock, and Utilization of Mechanical Circulatory Support Devices in Myocarditis (Analysis of National Inpatient Sample Data, 2005–2014)
Pahuja M, Adegbala O, Mishra T, Akintoye E, Chehab O, Mony S, Singh M, Ando T, Abubaker H, Yassin A, Subahi A, Shokr M, Ranka S, Briasoulis A, Kapur N, Burkhoff D, Afonso L. Trends in the Incidence of In-Hospital Mortality, Cardiogenic Shock, and Utilization of Mechanical Circulatory Support Devices in Myocarditis (Analysis of National Inpatient Sample Data, 2005–2014). Journal Of Cardiac Failure 2019, 25: 457-467. PMID: 31035007, DOI: 10.1016/j.cardfail.2019.04.012.Peer-Reviewed Original ResearchConceptsIncidence of CSCardiogenic shockMechanical circulatory supportHospital mortalityMCS devicesPercutaneous ventricular assist deviceNational Inpatient Sample databaseMechanical circulatory support devicesIncidence of myocarditisPercutaneous cardiopulmonary supportCases of myocarditisIn-Hospital MortalityExtracorporeal membrane oxygenationCirculatory support devicesVentricular assist deviceTandem HeartHemodynamic instabilityMultiple comorbiditiesCardiopulmonary supportEndomyocardial biopsyMembrane oxygenationTotal admissionsCirculatory supportPatient mortalityPoor prognosisCharacteristics and Outcomes of Patients with Cardiogenic Shock Complicated by Acute Kidney Injury Requiring Hemodialysis
Inampudi C, Adegbala O, Akintoye E, Alvarez P, Briasoulis A. Characteristics and Outcomes of Patients with Cardiogenic Shock Complicated by Acute Kidney Injury Requiring Hemodialysis. The Journal Of Heart And Lung Transplantation 2019, 38: s63. DOI: 10.1016/j.healun.2019.01.141.Peer-Reviewed Original ResearchLength of stayCardiogenic shockOutcomes of patientsHospital mortalityAcute Kidney Injury Requiring HemodialysisPre-existing chronic kidney diseasePropensity score-matched groupsHigher comorbidity burdenAcute kidney injuryChronic kidney diseaseRenal replacement therapyHospital-level characteristicsRenal venous pressureNational Inpatient SampleComorbidity burdenHospital morbidityHospital outcomesKidney injuryElixhauser scoreRenal functionBiventricular functionDiabetes mellitusRenal perfusionVenous pressureHospitalization costsCharacteristics and Outcomes of Patients With Cardiogenic Shock Utilizing Hemodialysis for Acute Kidney Injury
Adegbala O, Inampudi C, Adejumo A, Otuonye G, Akintoye E, Elsayed R, Williams K, Alvarez P, Afonso L, Briasoulis A. Characteristics and Outcomes of Patients With Cardiogenic Shock Utilizing Hemodialysis for Acute Kidney Injury. The American Journal Of Cardiology 2019, 123: 1816-1821. PMID: 30967283, DOI: 10.1016/j.amjcard.2019.02.038.Peer-Reviewed Original ResearchConceptsLength of stayAcute kidney injuryCardiogenic shockOutcomes of patientsHospital mortalityKidney injuryTemporary mechanical supportCause of CSPropensity score-matched groupsST-elevation myocardial infarctionMechanical circulatory support devicesHigher comorbidity burdenRenal replacement therapyElevation myocardial infarctionHospital-level characteristicsRenal venous pressureNational Inpatient SampleCirculatory support devicesComorbidity burdenHospital morbidityHospital outcomesRenal functionBiventricular functionRenal perfusionVenous pressurePredictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Briasoulis A, Telila T, Takagi H, Grines C, Schreiber T, Bhatt D, Afonso L. Predictors of Hospital Cost After Transcatheter Aortic Valve Implantation in the United States: From the Nationwide Inpatient Sample Database. The American Journal Of Cardiology 2019, 123: 1142-1148. PMID: 30658917, DOI: 10.1016/j.amjcard.2018.12.044.Peer-Reviewed Original ResearchMeSH KeywordsAged, 80 and overAortic Valve StenosisDatabases, FactualFemaleHospital CostsHospital MortalityHospitalizationHumansIncidenceInpatientsMalePatient Acceptance of Health CarePostoperative ComplicationsPropensity ScoreRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementUnited StatesConceptsTranscatheter aortic valve implantationNationwide Inpatient Sample databaseHigh-cost groupHigher hospitalization costsAortic valve implantationHospitalization costsValve implantationHospital costsSample databaseSurgical aortic valve replacementCost groupsHigher co-morbidity burdenAcute kidney injuryAcute respiratory failureAortic valve replacementPeripheral vascular diseaseCo-morbidity burdenCost of hospitalizationLength of stayMultivariable regression analysisLow-cost groupHigh incremental costPost-TAVITAVI hospitalizationsCardiogenic shockImpact of atrial fibrillation on patients hospitalized for acute myocarditis: Insights from a nationally‐representative United States cohort
Subahi A, Akintoye E, Yassin A, Abubakar H, Adegbala O, Mishra T, Abdelrahman M, Shokr M, Afonso L. Impact of atrial fibrillation on patients hospitalized for acute myocarditis: Insights from a nationally‐representative United States cohort. Clinical Cardiology 2019, 42: 26-31. PMID: 30284301, PMCID: PMC6436524, DOI: 10.1002/clc.23088.Peer-Reviewed Original ResearchConceptsAtrial fibrillationHospital mortalityHospital outcomesAcute myocarditisICD-9-CM diagnostic codesNon-routine hospital dischargeImpact of AFPropensity score-matched control groupAcute myocarditis patientsAcute kidney injuryUnited States cohortNational Inpatient SampleCardiac tamponadeCardiogenic shockCause mortalityKidney injuryMyocarditis patientsAM patientsHospital dischargeAF groupInpatient SamplePrimary diagnosisDiagnostic codesHigh riskGeneral population
2018
In‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample
Ahmed A, Akintoye E, Adegbala O, Yassin A, Subahi A, Bangura L, Abubakar H, Elder M, Shokr M, Afonso L. In‐hospital outcomes of transcatheter mitral valve repair with Mitraclip in patients with pulmonary hypertension: Insights from the National Inpatient Sample. Catheterization And Cardiovascular Interventions 2018, 94: e30-e36. PMID: 30506974, DOI: 10.1002/ccd.27997.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCardiac CatheterizationClinical Decision-MakingDatabases, FactualFemaleHeart Valve ProsthesisHeart Valve Prosthesis ImplantationHospital MortalityHumansHypertension, PulmonaryMaleMiddle AgedMitral ValveMitral Valve InsufficiencyPatient SelectionPostoperative ComplicationsPrevalenceProsthesis DesignRecovery of FunctionRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesConceptsTranscatheter mitral valve repairNational Inpatient SamplePulmonary hypertensionMitral valve repairHospital outcomesValve repairInpatient SamplePre-existing pulmonary hypertensionPrevalence of PHPostoperative deep vein thrombosisAcute respiratory failureCohort of patientsDeep vein thrombosisMedian hospital costsHemorrhage requiring transfusionLength of stayPH groupCardiogenic shockPostoperative sepsisRespiratory failureHome dischargeInpatient mortalityPeriprocedural outcomesProhibitive riskPulmonary embolismPredictors, Burden, and the Impact of Arrhythmia on Patients Admitted for Acute Myocarditis
Adegbala O, Olagoke O, Akintoye E, Adejumo A, Oluwole A, Jara C, Williams K, Briasoulis A, Afonso L. Predictors, Burden, and the Impact of Arrhythmia on Patients Admitted for Acute Myocarditis. The American Journal Of Cardiology 2018, 123: 139-144. PMID: 30539745, DOI: 10.1016/j.amjcard.2018.09.017.Peer-Reviewed Original ResearchConceptsImpact of arrhythmiasCardiac arrhythmiasAcute myocarditisNonroutine hospital dischargePredictors of arrhythmiasPropensity-matched analysisMechanical circulatory supportSudden cardiac deathOccurrence of arrhythmiasCost of hospitalizationLength of staySignificant proportionHospital mortalityCardiogenic shockHospital outcomesHospital dischargeMyocarditis casesCardiac deathIndependent predictorsPacemaker implantationAtrial fibrillationCirculatory supportCommon arrhythmiaVentricular tachycardiaWorse outcomesIncidence, Predictors, and In-Hospital Outcomes of Transcatheter Aortic Valve Implantation After Nonelective Admission in Comparison With Elective Admission: From the Nationwide Inpatient Sample Database
Ando T, Adegbala O, Villablanca P, Akintoye E, Ashraf S, Shokr M, Briasoulis A, Takagi H, Grines C, Afonso L, Schreiber T. Incidence, Predictors, and In-Hospital Outcomes of Transcatheter Aortic Valve Implantation After Nonelective Admission in Comparison With Elective Admission: From the Nationwide Inpatient Sample Database. The American Journal Of Cardiology 2018, 123: 100-107. PMID: 30360892, DOI: 10.1016/j.amjcard.2018.09.023.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve implantationNationwide Inpatient Sample databaseNonelective admissionsPropensity-matched cohortAortic valve implantationHospital mortalityValve implantationElective admissionsOutcomes of TAVITransarterial transcatheter aortic valve implantationSample databaseHigher adverse outcomesPulmonary circulation disordersAcute kidney injuryHealth resource utilizationIn-Hospital OutcomesChronic kidney diseaseIndependent risk factorCongestive heart failureHigh-risk cohortAcute myocardial infarctionCardiogenic shockHospital lengthKidney injuryRespiratory failure
2017
Burden of arrhythmias in peripartum cardiomyopathy: Analysis of 9841 hospitalizations
Mallikethi-Reddy S, Akintoye E, Trehan N, Sharma S, Briasoulis A, Jagadeesh K, Rubenfire M, Grines C, Afonso L. Burden of arrhythmias in peripartum cardiomyopathy: Analysis of 9841 hospitalizations. International Journal Of Cardiology 2017, 235: 114-117. PMID: 28268089, DOI: 10.1016/j.ijcard.2017.02.084.Peer-Reviewed Original ResearchMeSH KeywordsAdultArrhythmias, CardiacCardiomyopathiesDatabases, FactualElectric CountershockElectrophysiologic Techniques, CardiacFemaleHeart ArrestHospital CostsHospital MortalityHumansLength of StayOutcome and Process Assessment, Health CarePregnancyPregnancy Complications, CardiovascularSurvival AnalysisUnited StatesConceptsBurden of arrhythmiasPeripartum cardiomyopathyHospital mortalityHospitalization costsNationwide Inpatient Sample databaseElixhauser comorbidity scoreSwan-Ganz catheterizationFrequency of arrhythmiasLength of stayHealthcare Utilization ProjectArrhythmogenic causesCardiogenic shockComorbidity scorePPM implantationBalloon pumpCoronary angiographyElectrical cardioversionCatheter ablationSignificant morbidityInpatient stayCardiac arrestCommon arrhythmiaMean agePrimary diagnosisVentricular tachycardia