2020
Prospective, randomized, double-blind, placebo-controlled evaluation of the Pharmacokinetics, Safety and Efficacy of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia
Paidas MJ, Tita ATN, Macones GA, Saade GA, Ehrenkranz RA, Triche EW, Streisand JB, Lam GK, Magann EF, Lewis DF, Dombrowski MP, Werner EF, Branch DW, Habli MA, Grotegut CA, Silver RM, Longo SA, Amon E, Cleary K, How HY, Novotny SR, Grobman WA, Whiteman VE, Wing DA, Scifres CM, Sibai BM. Prospective, randomized, double-blind, placebo-controlled evaluation of the Pharmacokinetics, Safety and Efficacy of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia. American Journal Of Obstetrics And Gynecology 2020, 223: 739.e1-739.e13. PMID: 32780999, DOI: 10.1016/j.ajog.2020.08.004.Peer-Reviewed Original ResearchMeSH KeywordsAdministration, IntravenousAdolescentAdultAntithrombin ProteinsCesarean SectionDelivery, ObstetricDouble-Blind MethodFemaleFetal DistressGestational AgeHumansInfant, Premature, DiseasesInfant, Small for Gestational AgeMiddle AgedNeonatal SepsisPerinatal MortalityPre-EclampsiaPregnancyPregnancy Trimester, SecondPregnancy Trimester, ThirdProspective StudiesRecombinant ProteinsYoung AdultConceptsRecombinant human antithrombinPreterm preeclampsiaExpectant managementMorbidity scoreHuman antithrombinPlacebo-controlled clinical trialPlacebo-controlled evaluationPlacebo-controlled trialMedian gestational ageMaternal complicationsVersus PlaceboFetal outcomesMaternal outcomesPreterm deliveryEndothelial dysfunctionSecondary outcomesSingleton pregnanciesStandard therapyLoading dosePrimary outcomeWeeks' gestationGestational ageContinuous infusionClinical trialsSaline infusion
2019
Development and Testing of Improved Models to Predict Payment Using Centers for Medicare & Medicaid Services Claims Data
Krumholz HM, Warner F, Coppi A, Triche EW, Li SX, Mahajan S, Li Y, Bernheim SM, Grady J, Dorsey K, Desai NR, Lin Z, Normand ST. Development and Testing of Improved Models to Predict Payment Using Centers for Medicare & Medicaid Services Claims Data. JAMA Network Open 2019, 2: e198406. PMID: 31411709, PMCID: PMC6694388, DOI: 10.1001/jamanetworkopen.2019.8406.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionHeart failurePopulation-based programsPOA codesSingle diagnostic codeDiagnostic codesComparative effectiveness research studyPublic reportingIndex admission diagnosisDays of hospitalizationClinical Modification codesService claims dataAcute care hospitalsMultiple care settingsPatient-level modelsAdmission diagnosisTotal hospitalizationsCare hospitalPrevious diagnosisNinth RevisionMyocardial infarctionCandidate variablesCare settingsClaims dataMAIN OUTCOME
2018
Quantification characteristics of digital spiral analysis for understanding the relationship among tremor and clinical measures in persons with multiple sclerosis
DelMastro H, Ruiz J, Gromisch E, Garbalosa J, Triche E, Olson K, Lo A. Quantification characteristics of digital spiral analysis for understanding the relationship among tremor and clinical measures in persons with multiple sclerosis. Journal Of Neuroscience Methods 2018, 307: 254-259. PMID: 29940199, DOI: 10.1016/j.jneumeth.2018.06.016.Peer-Reviewed Original Research
2016
Changes in Cognitive Processing Speed, Mood, and Fatigue in an Observational Study of Persons With Multiple Sclerosis Treated With Dalfampridine-ER
Triche E, Ruiz J, Olson K, Lo A. Changes in Cognitive Processing Speed, Mood, and Fatigue in an Observational Study of Persons With Multiple Sclerosis Treated With Dalfampridine-ER. Clinical Neuropharmacology 2016, 39: 73-80. PMID: 26818040, DOI: 10.1097/wnf.0000000000000130.Peer-Reviewed Original ResearchConceptsDalfampridine extended releaseMultiple sclerosisWalk respondersObservational pre-post studyPre-post studyPerformance ScaleDegenerative neurological conditionDalfampridine-ERMS careFatigue scoresObservational studyResponder statusWeek 14Neurological conditionsSignificant improvementCognitive processing speedSelf-reported cognitionMood scoresWeeksSclerosisSDMTRespondersMoodDrugsDepression
2015
Pre-Pregnancy BMI, Gestational Weight Gain, and the Risk of Hypertensive Disorders of Pregnancy: A Cohort Study in Wuhan, China
Zhou A, Xiong C, Hu R, Zhang Y, Bassig BA, Triche E, Yang S, Qiu L, Zhang Y, Yao C, Xu S, Wang Y, Xia W, Qian Z, Zheng T, Zhang B. Pre-Pregnancy BMI, Gestational Weight Gain, and the Risk of Hypertensive Disorders of Pregnancy: A Cohort Study in Wuhan, China. PLOS ONE 2015, 10: e0136291. PMID: 26305565, PMCID: PMC4548954, DOI: 10.1371/journal.pone.0136291.Peer-Reviewed Original ResearchConceptsTotal gestational weight gainGestational weight gainRisk of HDPPre-pregnancy BMIRisk factorsHypertensive disordersCohort studyBMI gainEarly gestational weight gainMaternal pre-pregnancy BMIChinese womenWeight gainMultiple unconditional logistic regressionLive singleton pregnancyUnconditional logistic regressionNormal-weight counterpartsPutative risk factorsWeight control effortsSingleton pregnanciesMaternal deathsEarly pregnancyIOM recommendationsMedicine recommendationsElevated riskPregnancyEffects of dalfampridine on multi-dimensional aspects of gait and dexterity in multiple sclerosis among timed walk responders and non-responders
Lo A, Ruiz J, Koenig C, Anderson B, Olson K, Triche E. Effects of dalfampridine on multi-dimensional aspects of gait and dexterity in multiple sclerosis among timed walk responders and non-responders. Journal Of The Neurological Sciences 2015, 356: 77-82. PMID: 26139339, DOI: 10.1016/j.jns.2015.06.008.Peer-Reviewed Original ResearchConceptsNon-dominant sideMultiple sclerosisMultiple Sclerosis Walking Scale-12Six-Spot Step TestD-EREffects of dalfampridineMinute walk testHole Peg TestRoutine clinical careWalk respondersWalk testGait impairmentAmbulatory personsPeg TestGross dexterityClinical carePotential treatmentScale-12Block TestSclerosisGaitStep testRespondersFurther investigationSignificant improvementCigarette smoking and emergency care utilization among asthmatic adults in the 2011 Asthma Call-back Survey
Khokhawalla S, Rosenthal S, Pearlman D, Triche E. Cigarette smoking and emergency care utilization among asthmatic adults in the 2011 Asthma Call-back Survey. Journal Of Asthma 2015, 52: 732-739. PMID: 25563058, DOI: 10.3109/02770903.2015.1004337.Peer-Reviewed Original ResearchConceptsAsthma Call-back SurveyUrgent visitsCall-back SurveyAsthmatic adultsFormer smokersEmergency departmentEmergency careCurrent smokersED visitsEmergency care useEmergency care visitsCessation of smokingCross-sectional study designEmergency care utilizationMultivariable logistic regressionPopulation attributable riskPopulation-based estimatesHealth care costsFormer smokingAdult asthmaticsCare visitsCurrent smokingCare utilizationSmoking statusCigarette smokingA Pilot Study: examining the effects and tolerability of structured dance intervention for individuals with multiple sclerosis
Mandelbaum R, Triche E, Fasoli S, Lo A. A Pilot Study: examining the effects and tolerability of structured dance intervention for individuals with multiple sclerosis. Disability And Rehabilitation 2015, 38: 218-222. PMID: 25875049, DOI: 10.3109/09638288.2015.1035457.Peer-Reviewed Original ResearchConceptsDynamic Gait IndexPhysical activity adherenceMultiple sclerosisPhysical activityDance interventionActivities-specific Balance Confidence ScaleGodin Leisure Time QuestionnaireIssues of tolerabilityBalance Confidence ScaleEnjoyable physical activityActivity adherenceMS symptomsGait IndexNeurological impairmentMS populationElderly populationFeasible interventionPilot studyConfidence ScaleTolerabilityInterventionNeurodegenerative populationsSclerosisTime QuestionnaireBehavioral changes
2013
Mediterranean and Dietary Approaches to Stop Hypertension dietary patterns and risk of sudden cardiac death in postmenopausal women 1 , 2 , 3
Bertoia M, Triche E, Michaud D, Baylin A, Hogan J, Neuhouser M, Tinker L, Van Horn L, Waring M, Li W, Shikany J, Eaton C. Mediterranean and Dietary Approaches to Stop Hypertension dietary patterns and risk of sudden cardiac death in postmenopausal women 1 , 2 , 3. American Journal Of Clinical Nutrition 2013, 99: 344-351. PMID: 24351877, PMCID: PMC3893726, DOI: 10.3945/ajcn.112.056135.Peer-Reviewed Original ResearchConceptsSudden cardiac deathFood frequency questionnaireDASH dietary patternDietary patternsCardiac deathDiet scoreDietary ApproachesLower riskRisk of SCDHigher DASH diet scoreHigher Mediterranean diet scoreWomen's Health Initiative studyHypertension (DASH) dietary patternMediterranean diet scoreDASH diet scoreMediterranean dietary patternDevelopment of atherosclerosisHypertension (DASH) dietPostmenopausal womenProspective cohortSymptom onsetSodium intakeHighest quintileLowest quintileHigh intakeCombination of Robot-Assisted and Conventional Body-Weight–Supported Treadmill Training Improves Gait in Persons With Multiple Sclerosis
Ruiz J, Labas M, Triche E, Lo A. Combination of Robot-Assisted and Conventional Body-Weight–Supported Treadmill Training Improves Gait in Persons With Multiple Sclerosis. Journal Of Neurologic Physical Therapy 2013, 37: 187-193. PMID: 24189336, DOI: 10.1097/npt.0000000000000018.Peer-Reviewed Original ResearchConceptsFunctional Reach TestGait trainingDT groupTreadmill trainingWalk testTherapy groupIT groupRobot-assisted treadmill trainingImmediate therapy groupConcurrent comparison groupMajority of personsQuality of lifePre-post improvementsMultiple sclerosisEffective therapyReach testOutcome measuresBody weightFRT distancePhase ISame sessionVideo AbstractComparison groupPhase IIRobot-AssistedLong-term alcohol and caffeine intake and risk of sudden cardiac death in women 1 , 2 , 3
Bertoia M, Triche E, Michaud D, Baylin A, Hogan J, Neuhouser M, Freiberg M, Allison M, Safford M, Li W, Mossavar-Rahmani Y, Rosal M, Eaton C. Long-term alcohol and caffeine intake and risk of sudden cardiac death in women 1 , 2 , 3. American Journal Of Clinical Nutrition 2013, 97: 1356-1363. PMID: 23615825, PMCID: PMC3652927, DOI: 10.3945/ajcn.112.044248.Peer-Reviewed Original ResearchConceptsRisk of SCDSudden cardiac deathLong-term alcoholCaffeine intakeCardiac deathBaseline intakeWomen's Health Initiative Observational StudyDecaffeinated coffeeCumulative average intakeRegular tea intakeFood frequency questionnaireBody mass indexRecent alcohol intakeTotal caffeine intakeAlcohol/dHeart rate variabilityPostmenopausal womenBlood pressureHormone useMass indexAlcohol intakeTea intakeRecent intakeObservational studyTotal caffeine
2012
Fetal growth and later maternal death, cardiovascular disease and diabetes
LYKKE JA, PAIDAS MJ, TRICHE EW, LANGHOFF‐ROOS J. Fetal growth and later maternal death, cardiovascular disease and diabetes. Acta Obstetricia Et Gynecologica Scandinavica 2012, 91: 503-510. PMID: 22372730, DOI: 10.1111/j.1600-0412.2011.01355.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultBirth WeightCardiovascular DiseasesCohort StudiesDenmarkDiabetes MellitusFemaleFetal DevelopmentFollow-Up StudiesHealth Status IndicatorsHumansInfant, NewbornMiddle AgedMortality, PrematurePregnancyProportional Hazards ModelsReference StandardsRegistriesRetrospective StudiesRiskYoung AdultConceptsSubsequent maternal deathIschemic heart diseaseFetal growthPonderal indexMaternal deathsStandardized birthweightHeart diseaseCardiovascular diseaseSubsequent mortalityCox proportional hazards modelFirst singleton deliverySmaller risk estimatesSubsequent diabetes mellitusRetrospective cohort studyProportional hazards modelCardiovascular morbidityPregnancy complicationsCohort studySingleton deliveriesDiabetes mellitusGestational ageLow birthweightPrimary exposureSubsequent riskEarly death
2011
Changes in Sexual Risk Behavior Before and After HIV Seroconversion in Southern African Women Enrolled in a HIV Prevention Trial
Venkatesh K, de Bruyn G, Mayer K, Cheng H, Blanchard K, Ramjee G, Chipato T, Triche E, Padian N, van der Straten A. Changes in Sexual Risk Behavior Before and After HIV Seroconversion in Southern African Women Enrolled in a HIV Prevention Trial. JAIDS Journal Of Acquired Immune Deficiency Syndromes 2011, 57: 435-441. PMID: 21546849, DOI: 10.1097/qai.0b013e318220379b.Peer-Reviewed Original ResearchConceptsSexual risk behaviorsHIV seroconversionRisk behaviorsStudy visitSouthern African womenAnal sexSex partnersCondom useConsistent male condom useImproving Reproductive HealthHIV prevention trialsMale sex partnersMale condom useConsistent condom useSexual behaviorEpisodes of sexAfrican womenSecondary preventionHIV infectionHIV testingHIV statusPrevention trialsAfrica trialSeroconversionFemale condomSexual Risk Behaviors Among HIV-Infected South African Men and Women with Their Partners in a Primary Care Program: Implications for Couples-Based Prevention
Venkatesh K, de Bruyn G, Lurie M, Modisenyane T, Triche E, Gray G, Welte A, Martinson N. Sexual Risk Behaviors Among HIV-Infected South African Men and Women with Their Partners in a Primary Care Program: Implications for Couples-Based Prevention. AIDS And Behavior 2011, 16: 139-150. PMID: 21476005, PMCID: PMC3184366, DOI: 10.1007/s10461-011-9941-y.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-Retroviral AgentsBlack PeopleCD4 Lymphocyte CountCross-Sectional StudiesFamily CharacteristicsFemaleHIV InfectionsHumansMaleMiddle AgedPrevalencePrimary Health CareRisk-TakingSelf DisclosureSexual BehaviorSexual PartnersSocioeconomic FactorsSouth AfricaSurveys and QuestionnairesUrban PopulationYoung AdultConceptsHIV-positive partnerStatus unknown partnersSexual risk behaviorsPrimary care programsAntiretroviral therapyRisk behaviorsSouth African menCare programPartner's HIV statusAfrican menUnknown partnersActive HIVHIV statusHIV preventionHIVSex partnersUnprotected sexSex actsPreventionSexual behaviorMonthsWomenSexMenTherapyEffect of robot-assisted versus conventional body-weight-supported treadmill training on quality of life for people with multiple sclerosis
Wier L, Hatcher M, Triche E, Lo A. Effect of robot-assisted versus conventional body-weight-supported treadmill training on quality of life for people with multiple sclerosis. The Journal Of Rehabilitation Research And Development 2011, 48: 483. PMID: 21674396, DOI: 10.1682/jrrd.2010.03.0035.Peer-Reviewed Original ResearchConceptsQuality of lifeTreadmill trainingPhysical component summary scoreComponent summary scoresMultiple sclerosis patientsQOL outcome measuresTraining sessionsGait dysfunctionSclerosis patientsMultiple sclerosisGait impairmentBWSTTOutcome measuresQOL measuresSummary scoresLongitudinal changesPilot studySignificant differencesQoLR groupSignificant improvementSessionsSclerosisPatientsDysfunction
2010
Speed- and cane-related alterations in gait parameters in individuals with multiple sclerosis
Gianfrancesco M, Triche E, Fawcett J, Labas M, Patterson T, Lo A. Speed- and cane-related alterations in gait parameters in individuals with multiple sclerosis. Gait & Posture 2010, 33: 140-142. PMID: 20952198, DOI: 10.1016/j.gaitpost.2010.09.016.Peer-Reviewed Original ResearchConceptsGait parametersPreferred speedMultiple sclerosisGait impairmentMS populationBilateral coordinationAdditional trialsStance timeMS participantsCane useSwing timeStride lengthDouble supportDaily activitiesStep length ratioSingle supportAssistive devicesParticipantsIndividualsSclerosisMaximal speedImpairmentTrialsDaily
2009
Preterm delivery and risk of subsequent cardiovascular morbidity and type‐II diabetes in the mother
Lykke J, Paidas M, Damm P, Triche E, Kuczynski E, Langhoff‐Roos J. Preterm delivery and risk of subsequent cardiovascular morbidity and type‐II diabetes in the mother. BJOG An International Journal Of Obstetrics & Gynaecology 2009, 117: 274-281. PMID: 20015308, DOI: 10.1111/j.1471-0528.2009.02448.x.Peer-Reviewed Original ResearchConceptsRisk of thromboembolismType II diabetesPreterm deliveryCardiovascular morbiditySingleton deliveriesRegistry-based retrospective cohort studyCox proportional hazards modelFirst singleton deliveryHypertensive pregnancy disordersMaternal cardiovascular morbiditySecond singleton deliverySpecific cardiovascular eventsSubsequent cardiovascular morbidityRetrospective cohort studyIschemic heart diseaseWeeks of gestationYear of deliveryProportional hazards modelFetal growth deviationsMaternal hypertensionAdjusted riskCardiovascular eventsPlacental abruptionPregnancy complicationsCohort study
2008
Improving Gait in Multiple Sclerosis Using Robot-Assisted, Body Weight Supported Treadmill Training
Lo A, Triche E. Improving Gait in Multiple Sclerosis Using Robot-Assisted, Body Weight Supported Treadmill Training. Neurorehabilitation And Neural Repair 2008, 22: 661-671. PMID: 18971381, DOI: 10.1177/1545968308318473.Peer-Reviewed Original ResearchConceptsExpanded Disability Status ScaleMultiple sclerosisGait outcomesGait impairmentTreadmill trainingGait trainingTreatment groupsBody weightBaseline Expanded Disability Status ScaleKurtzke Expanded Disability Status ScalePrimary progressive multiple sclerosisDouble limb support timeProgressive gait impairmentProgressive multiple sclerosisDisability Status ScaleMajority of patientsSmall pilot studyGait functionStatus ScaleTreatment gapAffected limbOutpatient interventionStudy populationSupport timeCrossover design
2000
Abortion and Its Effect on Risk of Preeclampsia and Transient Hypertension
Eras J, Saftlas A, Triche E, Hsu C, Risch H, Bracken M. Abortion and Its Effect on Risk of Preeclampsia and Transient Hypertension. Epidemiology 2000, 11: 36-43. PMID: 10615841, DOI: 10.1097/00001648-200001000-00009.Peer-Reviewed Original ResearchConceptsRisk of preeclampsiaTransient hypertensionNulliparous womenDecreased riskMore abortionsPregnancy-related risk factorsHistory of abortionHypertensive disordersWeeks' gestationGestational ageSubsequent pregnancyPrenatal careRisk factorsObstetric practicePrior abortionMonths gestationPreeclampsiaHypertensionInduced abortionReproductive historyReferent groupProtective factorsGestationWomenAbortion