2016
Physical Activity During Pregnancy and Subsequent Risk of Preeclampsia and Gestational Hypertension: A Case Control Study
Spracklen C, Ryckman K, Triche E, Saftlas A. Physical Activity During Pregnancy and Subsequent Risk of Preeclampsia and Gestational Hypertension: A Case Control Study. Maternal And Child Health Journal 2016, 20: 1193-1202. PMID: 26910608, PMCID: PMC5538351, DOI: 10.1007/s10995-016-1919-y.Peer-Reviewed Original ResearchConceptsRisk of preeclampsiaLeisure-time PAGestational hypertensionSedentary activitiesMedical chart reviewCase-control studyGestational hypertensiveObjectivePhysical activityPreeclampsia resultsPregnancy hypertensionPrepregnancy BMINormotensive womenChart reviewHypertension riskPreeclampsia riskSubsequent riskPreeclampsiaEpidemiologic studiesPA exposurePhysical activityMultinomial logistic regressionHypertensionControl studyDisease statusBirth records
2014
Genetic Predisposition to Dyslipidemia and Risk of Preeclampsia
Spracklen CN, Saftlas AF, Triche EW, Bjonnes A, Keating B, Saxena R, Breheny PJ, Dewan AT, Robinson JG, Hoh J, Ryckman KK. Genetic Predisposition to Dyslipidemia and Risk of Preeclampsia. American Journal Of Hypertension 2014, 28: 915-923. PMID: 25523295, PMCID: PMC4542907, DOI: 10.1093/ajh/hpu242.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiomarkersBlood PressureCase-Control StudiesChi-Square DistributionCholesterol, HDLCholesterol, LDLDyslipidemiasFemaleGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansIowaLogistic ModelsMultivariate AnalysisOdds RatioPhenotypePolymorphism, Single NucleotidePre-EclampsiaPregnancyRisk FactorsTriglyceridesYoung Adult
2013
Cumulative exposure to paternal seminal fluid prior to conception and subsequent risk of preeclampsia
Saftlas A, Rubenstein L, Prater K, Harland K, Field E, Triche E. Cumulative exposure to paternal seminal fluid prior to conception and subsequent risk of preeclampsia. Journal Of Reproductive Immunology 2013, 101: 104-110. PMID: 24011785, DOI: 10.1016/j.jri.2013.07.006.Peer-Reviewed Original ResearchConceptsRisk of preeclampsiaVaginal exposureNulliparous womenImmune maladaptation hypothesisOdds of preeclampsiaMedical chart reviewPercentile of exposureBarrier contraceptive methodsCase-control studyVaginal sexual intercourseAllogeneic fetusChart reviewIowa womenPaternal HLAAntigen exposureImmune toleranceNormotensive controlsPaternal antigensMaternal tolerancePreeclampsia casesPreeclampsia riskSubsequent riskSeminal fluidLive birthsContraceptive useMaternal–fetal HLA sharing and preeclampsia: variation in effects by seminal fluid exposure in a case–control study of nulliparous women in Iowa
Triche E, Harland K, Field E, Rubenstein L, Saftlas A. Maternal–fetal HLA sharing and preeclampsia: variation in effects by seminal fluid exposure in a case–control study of nulliparous women in Iowa. Journal Of Reproductive Immunology 2013, 101: 111-119. PMID: 23998333, PMCID: PMC4060772, DOI: 10.1016/j.jri.2013.06.004.Peer-Reviewed Original ResearchConceptsCase-control studyHLA sharingSemen exposureNulliparous womenClass IHLA typingComplete HLA typingMaternal-fetal histocompatibilityOdds of preeclampsiaMother-baby pairsHLA-A matchingVaginal exposureNormotensive controlsSuccessful pregnancyPreeclampsia casesContraceptive usePreeclampsiaEligibility criteriaFluid exposureIngestion practicesClass IIMultivariate modelStudy sampleExposure historyType of practice
2012
Correction of Systematic Bias in Ultrasound Dating in Studies of Small-for-Gestational-Age Birth: An Example From the Iowa Health in Pregnancy Study
Harland K, Saftlas A, Wallis A, Yankowitz J, Triche E, Zimmerman M. Correction of Systematic Bias in Ultrasound Dating in Studies of Small-for-Gestational-Age Birth: An Example From the Iowa Health in Pregnancy Study. American Journal Of Epidemiology 2012, 176: 443-455. PMID: 22886591, PMCID: PMC3499119, DOI: 10.1093/aje/kws120.Peer-Reviewed Original ResearchConceptsLast menstrual periodUltrasound gestational ageGestational ageSGA birthEarly ultrasoundPreterm deliveryPopulation-based case-control studyFirst trimester vaginal bleedingFirst trimester prenatal careGestational age fetusesGestational-age birthsCase-control studyStandard guidelinesMultivariable linear regressionDifferent study populationsVaginal bleedingGestational durationSGA fetusesSGA subjectsPrenatal careMaternal ageMenstrual periodPregnancy StudyStudy populationUnadjusted models
2004
Optimizing Buccal Cell DNA Yields in Mothers and Infants for Human Leukocyte Antigen Genotyping
Saftlas A, Waldschmidt M, Logsden-Sackett N, Triche E, Field E. Optimizing Buccal Cell DNA Yields in Mothers and Infants for Human Leukocyte Antigen Genotyping. American Journal Of Epidemiology 2004, 160: 77-84. PMID: 15229120, DOI: 10.1093/aje/kwh171.Peer-Reviewed Original Research