Caffeine Metabolites in Umbilical Cord Blood, Cytochrome P-450 1A2 Activity, and Intrauterine Growth Restriction
Grosso LM, Triche EW, Belanger K, Benowitz NL, Holford TR, Bracken MB. Caffeine Metabolites in Umbilical Cord Blood, Cytochrome P-450 1A2 Activity, and Intrauterine Growth Restriction. American Journal Of Epidemiology 2006, 163: 1035-1041. PMID: 16641310, DOI: 10.1093/aje/kwj125.Peer-Reviewed Original ResearchConceptsIntrauterine growth restrictionRisk of IUGRUmbilical cord bloodGrowth restrictionCord bloodCaffeine consumptionRatio of paraxanthineCytochrome PSelf-reported caffeine consumptionPreterm deliveryFetal exposureHighest quartileAdjusted analysisPregnant womenFetal growthObstetric practiceCYP1A2 activityParaxanthine levelsReproductive outcomesAdjusted modelAssociation of caffeineCaffeine metabolitesStandard deviation changeConflicting resultsQuartile