High-Resolution and High-Sensitivity Spread Field Imaging to Differentiate Sub-endocardium and Sub-epicardium in Cardiac SPECT — A Preliminary Phantom Study
Mu Z, Palyo R, Goyal D, Sandoval V, Mu Z, Tao Z, Sinusas A, Miller E, Liu Y. High-Resolution and High-Sensitivity Spread Field Imaging to Differentiate Sub-endocardium and Sub-epicardium in Cardiac SPECT — A Preliminary Phantom Study. 2022, 00: 1-4. DOI: 10.1109/nss/mic44845.2022.10399016.Peer-Reviewed Original ResearchTc-99m solutionHole imagesCardiac SPECTCardiac phantomMyocardial perfusion defectsField imagesParallel hole collimatorResolution of SPECTSub-endocardiumSubset expectation maximizationCZT detectorsSub-epicardiumHole collimatorPerfusion defectsHigh-resolutionOSEM algorithmCollimatorPhantom studyScanner configurationReconstruction technologyPhantomSPECT slicesTransmural perfusion gradientExpectation maximizationOSEMDifferences in Prognostic Value of Myocardial Perfusion Single-Photon Emission Computed Tomography Using High-Efficiency Solid-State Detector Between Men and Women in a Large International Multicenter Study
Tamarappoo BK, Otaki Y, Sharir T, Hu LH, Gransar H, Einstein AJ, Fish MB, Ruddy TD, Kaufmann P, Sinusas AJ, Miller EJ, Bateman TM, Dorbala S, Di Carli M, Eisenberg E, Liang JX, Dey D, Berman DS, Slomka PJ. Differences in Prognostic Value of Myocardial Perfusion Single-Photon Emission Computed Tomography Using High-Efficiency Solid-State Detector Between Men and Women in a Large International Multicenter Study. Circulation Cardiovascular Imaging 2022, 15: e012741. PMID: 35727872, PMCID: PMC9307118, DOI: 10.1161/circimaging.121.012741.Peer-Reviewed Original ResearchConceptsMajor adverse cardiac eventsTotal perfusion defectPrognostic valuePerfusion defectsSingle photon emissionLarge international multicenter studyMyocardial perfusion single-photon emissionPerfusion single-photon emissionStress SPECT myocardial perfusion imagingSPECT myocardial perfusion imagingAdverse cardiac eventsMACE-free survivalMultivariable Cox modelSingle-center studyGreater prognostic valueInternational multicenter studyProportional hazards modelMyocardial perfusion defectsMyocardial perfusion imagingREFINE SPECT registryConventional single-photon emissionCardiac eventsHazard ratioEjection fractionMulticenter study