Featured Publications
Early Adversity and Development: Parsing Heterogeneity and Identifying Pathways of Risk and Resilience
Gee DG. Early Adversity and Development: Parsing Heterogeneity and Identifying Pathways of Risk and Resilience. American Journal Of Psychiatry 2021, 178: 998-1013. PMID: 34734741, DOI: 10.1176/appi.ajp.2021.21090944.Peer-Reviewed Original ResearchMeSH KeywordsAdverse Childhood ExperiencesEarly Medical InterventionHumansMental DisordersMental HealthProtective FactorsPsychopathologyRisk FactorsConceptsEarly adversityProtective factorsEffects of adversityOnset of psychopathologyPathways of riskNeurodevelopmental trajectoriesMajor risk factorAdversityMental healthNeurodevelopmental pathwaysEarly environmentPsychopathologySpecific dimensionsIntervention strategiesFuture researchRisk factorsEarly risk identificationTreatment approachesImmense burdenConceptual modelDevelopmental timingResilienceOngoing refinementRiskFactors
2020
Influences of early‐life stress on frontolimbic circuitry: Harnessing a dimensional approach to elucidate the effects of heterogeneity in stress exposure
Cohodes EM, Kitt ER, Baskin‐Sommers A, Gee DG. Influences of early‐life stress on frontolimbic circuitry: Harnessing a dimensional approach to elucidate the effects of heterogeneity in stress exposure. Developmental Psychobiology 2020, 63: 153-172. PMID: 32227350, DOI: 10.1002/dev.21969.Peer-Reviewed Original ResearchConceptsEarly life stressFrontolimbic circuitryStress exposurePhysical health problemsEffects of stressCircuit maturationGlucocorticoid receptorHealth problemsMajority of studiesMental healthExposure influencePsychobiological effectsDimensional approachEarly experienceDifferential outcomesOutcomesSubsequent vulnerabilityRiskVast heterogeneityExposureInnervationCircuitryBrainSeverityCaregivers