2004
Interaction and Transmission of Two Borrelia burgdorferi Sensu Stricto Strains in a Tick-Rodent Maintenance System
Derdáková M, Dudiòák V, Brei B, Brownstein J, Schwartz I, Fish D. Interaction and Transmission of Two Borrelia burgdorferi Sensu Stricto Strains in a Tick-Rodent Maintenance System. Applied And Environmental Microbiology 2004, 70: 6783-6788. PMID: 15528545, PMCID: PMC525125, DOI: 10.1128/aem.70.11.6783-6788.2004.Peer-Reviewed Original ResearchConceptsB. burgdorferi sensu strictoBurgdorferi sensu strictoXenodiagnostic ticksBorrelia burgdorferi sensu strictoUninfected larval ticksGroups of miceWhite-footed miceTransmission cycleControl miceInfected micePrimary infectionExperimental miceI. scapularis ticksLeucopus miceDouble infectionMiceLyme disease agentInfectionScapularis ticksMajor genotypesWeekly intervalsTransmission dynamicsExperimental groupSame strainLarval ticks
2001
Interference Between the Agents of Lyme Disease and Human Granulocytic Ehrlichiosis in a Natural Reservoir Host
Levin M, Fish D. Interference Between the Agents of Lyme Disease and Human Granulocytic Ehrlichiosis in a Natural Reservoir Host. Vector-Borne And Zoonotic Diseases 2001, 1: 139-148. PMID: 12653144, DOI: 10.1089/153036601316977741.Peer-Reviewed Original ResearchConceptsHuman granulocytic ehrlichiosisE. phagocytophilaB. burgdorferiGranulocytic ehrlichiosisLyme diseaseB. burgdorferi challengeGroups of miceB. burgdorferi-infected miceBurgdorferi-infected miceXenodiagnostic larvaeI. scapularis larvaeUninfected miceNatural reservoir hostsControl miceInfectious challengePrimary infectionXenodiagnostic ticksControl groupMiceInfectionMixed infectionsI. scapularis nymphsBurgdorferiWeekly intervalsSecond agentOspA Immunization Decreases Transmission of Borrelia burgdorferi Spirochetes from Infected Peromyscus leucopus Mice to Larval Ixodes scapularis Ticks
Tsao J, Barbour A, Luke C, Fikrig E, Fish D. OspA Immunization Decreases Transmission of Borrelia burgdorferi Spirochetes from Infected Peromyscus leucopus Mice to Larval Ixodes scapularis Ticks. Vector-Borne And Zoonotic Diseases 2001, 1: 65-74. PMID: 12653137, DOI: 10.1089/153036601750137705.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, WildAntibodies, BacterialAntigens, SurfaceArachnid VectorsBacterial Outer Membrane ProteinsBacterial VaccinesBorrelia burgdorferiDisease ReservoirsDose-Response Relationship, ImmunologicEnzyme-Linked Immunosorbent AssayFluorescent Antibody Technique, DirectHost-Parasite InteractionsIxodesLarvaLipoproteinsLyme DiseasePeromyscusConceptsControl miceUninfected larval ticksInfection prevalenceLarval Ixodes scapularis ticksB. burgdorferiNumber of spirochetesEnzyme-linked immunosorbentBorrelia burgdorferi spirochetesLevel of immunizationReservoir hostsConcentration of antibodyBorrelia burgdorferi transmissionIxodes scapularis ticksSecond vaccinationImmunized miceInfected miceLarval ticksPrior infectionVaccination programSubsequent riskDecrease transmissionOspA vaccinationDirect immunofluorescenceImmune responseXenodiagnostic ticks
2000
Immunity Reduces Reservoir Host Competence of Peromyscus leucopus forEhrlichia phagocytophila
Levin M, Fish D. Immunity Reduces Reservoir Host Competence of Peromyscus leucopus forEhrlichia phagocytophila. Infection And Immunity 2000, 68: 1514-1518. PMID: 10678968, PMCID: PMC97309, DOI: 10.1128/iai.68.3.1514-1518.2000.Peer-Reviewed Original ResearchConceptsE. phagocytophilaControl miceImmune responseNonimmune control miceWhite-footed miceSame agentsMajority of miceStrong immune responsePrevalence of infectionXenodiagnostic larvaeImmunized miceTick biteXenodiagnostic ticksIxodes scapularis nymphsControl groupSingle infectionEhrlichia phagocytophilaMiceUninfected ticksInfectionPartial protectionWeeksImmunityScapularis nymphsReservoir host competence