1997
Two EGF molecules contribute additively to stabilization of the EGFR dimer
Lemmon M, Bu Z, Ladbury J, Zhou M, Pinchasi D, Lax I, Engelman D, Schlessinger J. Two EGF molecules contribute additively to stabilization of the EGFR dimer. The EMBO Journal 1997, 16: 281-294. PMID: 9029149, PMCID: PMC1169635, DOI: 10.1093/emboj/16.2.281.Peer-Reviewed Original ResearchConceptsEpidermal growth factorReceptor dimerizationEGF moleculesPrecise molecular detailsHuman growth hormone receptorReceptor-receptor interactionsGrowth factorInterferon-gamma receptorEGFR dimersSignaling eventsMolecular detailsReceptor oligomerizationGrowth hormone receptorExtracellular domainEGFR familyCell surfaceMonomer bindsSubsequent associationDimerizationHormone receptorsTitration calorimetrySmall-angle X-ray scatteringBindingReceptorsMultivalent binding
1994
Rotational orientation of transmembrane α-helices in bacteriorhodopsin A neutron diffraction study
Samatey F, Zaccaï G, Engelman D, Etchebest C, Popot J. Rotational orientation of transmembrane α-helices in bacteriorhodopsin A neutron diffraction study. Journal Of Molecular Biology 1994, 236: 1093-1104. PMID: 8120889, DOI: 10.1016/0022-2836(94)90014-0.Peer-Reviewed Original Research
1990
Membrane protein folding and oligomerization: the two-stage model.
Popot J, Engelman D. Membrane protein folding and oligomerization: the two-stage model. Biochemistry 1990, 29: 4031-7. PMID: 1694455, DOI: 10.1021/bi00469a001.Peer-Reviewed Original ResearchMeSH KeywordsBacteriorhodopsinsIon ChannelsLipid BilayersMembrane ProteinsModels, ChemicalProtein ConformationSolubilityConceptsMembrane protein foldingIntegral membrane proteinsMembrane proteinsProtein foldingMembrane protein subunitsTransmembrane segmentsTransmembrane structureSequence dataProtein subunitsVariety of functionsAqueous channelsLipid bilayersFoldingProteinSubunitsOligomerizationAssemblyFragmentsBilayers
1977
Model calculations of protein pair interference functions
Moore P, Engelman D. Model calculations of protein pair interference functions. Journal Of Molecular Biology 1977, 112: 228-234. PMID: 875017, DOI: 10.1016/s0022-2836(77)80140-x.Peer-Reviewed Original Research
1972
Molecular Mechanism for the Interaction of Phospholipid with Cholesterol
ROTHMAN J, ENGELMAN D. Molecular Mechanism for the Interaction of Phospholipid with Cholesterol. Nature 1972, 237: 42-44. PMID: 4503742, DOI: 10.1038/newbio237042a0.Peer-Reviewed Original Research