1983
Pair distribution functions of bacteriorhodopsin and rhodopsin in model bilayers
Pearson L, Chan S, Lewis B, Engelman D. Pair distribution functions of bacteriorhodopsin and rhodopsin in model bilayers. Biophysical Journal 1983, 43: 167-174. PMID: 6616005, PMCID: PMC1329246, DOI: 10.1016/s0006-3495(83)84337-9.Peer-Reviewed Original Research
1981
The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis
Engelman D, Steitz T. The spontaneous insertion of proteins into and across membranes: The helical hairpin hypothesis. Cell 1981, 23: 411-422. PMID: 7471207, DOI: 10.1016/0092-8674(81)90136-7.Peer-Reviewed Original ResearchConceptsMembrane proteinsSecreted proteinsIntegral membrane proteinsHydrophobic leader peptideSecretion of proteinsHelical hairpinSpecific membrane receptorsPolypeptide sequenceSecond helixLeader peptideTransport proteinsLipid environmentTerminal helixN-terminusSpontaneous insertionMembrane receptorsHairpin structurePolypeptide structureProteinHelixHairpinHydrophobic interiorOnly alphaNonpolar sequencesHydrophobic portion
1976
Compositional mapping of cholesteryl ester droplets in the fatty streaks of human aorta.
Hillman G, Engelman D. Compositional mapping of cholesteryl ester droplets in the fatty streaks of human aorta. Journal Of Clinical Investigation 1976, 58: 1008-1018. PMID: 965482, PMCID: PMC333265, DOI: 10.1172/jci108524.Peer-Reviewed Original Research