2024
Association Between High-Sensitivity Troponin (hs-cTnT) and Diagnosis of Myocarditis in Previously Healthy Pediatric Patients
Degen M, Leviter J, Bradley A, Karnik R, Ferdman D, McCollum S, Faherty E. Association Between High-Sensitivity Troponin (hs-cTnT) and Diagnosis of Myocarditis in Previously Healthy Pediatric Patients. Pediatric Cardiology 2024, 1-7. PMID: 39126513, DOI: 10.1007/s00246-024-03621-7.Peer-Reviewed Original ResearchDiagnosis of myocarditisPediatric patientsHs-cTnTTroponin levelsCardiac diagnosisHigh-sensitivity troponin THealthy pediatric patientsHigh-sensitivity troponinHs-cTnT groupMedian peak levelSensitivity troponin levelsElevated hs-cTnTCut-off valueInitial troponin levelMyocarditis diagnosisAcute myocarditisTroponin valuesCardiac troponinPediatric populationTroponin TMyocarditisPatientsPeak levelsDiagnosisMyocardial tissueImproving Palivizumab Administration to High-Risk Infants with Heart Disease via a Communication-Based Quality Improvement Initiative
Leone D, Rodriguez A, Cowenhoven K, O’Connell M, Grossman M, Ferdman D. Improving Palivizumab Administration to High-Risk Infants with Heart Disease via a Communication-Based Quality Improvement Initiative. Pediatric Cardiology 2024, 1-9. PMID: 38300318, DOI: 10.1007/s00246-023-03388-3.Peer-Reviewed Original ResearchHigh-risk infantsPercentage of infantsRate of administrationPalivizumab administrationPalivizumab dosesRespiratory syncytial virus seasonHeart diseaseDose of palivizumabCongenital heart diseasePediatric cardiac patientsPalivizumab eligibilityEligible infantsPalivizumab treatmentVirus seasonPalivizumabHeart CenterCardiac patientsInfantsOxygen saturationDoseDiagnosis codesQuality improvement initiativesAdministrationBaseline rateMultidisciplinary team
2023
Congenitally Corrected Transposition of the Great Arteries: Fetal Diagnosis, Associations, and Postnatal Outcome: A Fetal Heart Society Research Collaborative Study
Cohen J, Arya B, Caplan R, Donofrio M, Ferdman D, Harrington J, Ho D, Hogan W, Hornberger L, Jhaveri S, Killen S, Lindblade C, Michelfelder E, Moon‐Grady A, Patel S, Quezada E, Ronai C, Mejia A, Schidlow D, Stiver C, Thakur V, Srivastava S. Congenitally Corrected Transposition of the Great Arteries: Fetal Diagnosis, Associations, and Postnatal Outcome: A Fetal Heart Society Research Collaborative Study. Journal Of The American Heart Association 2023, 12: e029706. PMID: 37259984, PMCID: PMC10381988, DOI: 10.1161/jaha.122.029706.Peer-Reviewed Original ResearchMeSH KeywordsArrhythmias, CardiacAtrioventricular BlockCongenitally Corrected Transposition of the Great ArteriesFemaleFetal DeathFetal HeartFollow-Up StudiesHeart Defects, CongenitalHumansInfantPregnancyPrenatal DiagnosisPulmonary AtresiaRetrospective StudiesTransposition of Great VesselsTricuspid Valve InsufficiencyConceptsDeath/transplantSerial fetal echocardiogramsTricuspid regurgitationAortic obstructionPulmonary atresiaFetal deathGreat arteriesFetal echocardiogramFetal diagnosisAssociated cardiac defectsAssociated cardiac lesionsPulmonary outflow obstructionMedian gestational ageMild tricuspid regurgitationFetal tricuspid regurgitationBiventricular repairExtracardiac anomaliesOutflow obstructionSerial echocardiogramsCardiac lesionsClinical outcomesFetal factorsGestational ageUnivariable analysisAtrioventricular blockLeft ventricular strain in pediatric patients with bicuspid aortic valves and aortopathy
Frye R, Ittleman B, Shabanova V, Sugeng L, Steele J, Ferdman D, Karnik R. Left ventricular strain in pediatric patients with bicuspid aortic valves and aortopathy. Progress In Pediatric Cardiology 2023, 69: 101636. DOI: 10.1016/j.ppedcard.2023.101636.Peer-Reviewed Original ResearchBicuspid aortic valveLeft ventricular strainVentricular strainGlobal longitudinal strainGlobal circumferential strainAortic valvePediatric patientsEjection fractionLeft ventricle global longitudinal strainLeft ventricular global longitudinal strainBackground Bicuspid aortic valveVentricle global longitudinal strainSingle-center retrospective studyVentricular global longitudinal strainCommon congenital cardiac defectLongitudinal strainCircumferential strainAortic valve replacementNormal ejection fractionPrior cardiac interventionCongenital cardiac defectsYears of agePotential early markerLeft ventricular myocardiumSignificant differencesIMPROVING PALIVIZUMAB ADMINISTRATION TO HIGH-RISK INFANTS WITH CONGENITAL HEART DISEASE VIA A COMMUNICATION-BASED QUALITY IMPROVEMENT INITIATIVE
Leone D, Rodriguez A, Cowenhoven K, Grossman M, Ferdman D. IMPROVING PALIVIZUMAB ADMINISTRATION TO HIGH-RISK INFANTS WITH CONGENITAL HEART DISEASE VIA A COMMUNICATION-BASED QUALITY IMPROVEMENT INITIATIVE. Journal Of The American College Of Cardiology 2023, 81: 1604. DOI: 10.1016/s0735-1097(23)02048-x.Peer-Reviewed Original Research
2022
Longitudinal Assessment of Global and Regional Left Ventricular Strain in Patients with Multisystem Inflammatory Syndrome in Children (MIS-C)
He M, Leone DM, Frye R, Ferdman DJ, Shabanova V, Kosiv KA, Sugeng L, Faherty E, Karnik R. Longitudinal Assessment of Global and Regional Left Ventricular Strain in Patients with Multisystem Inflammatory Syndrome in Children (MIS-C). Pediatric Cardiology 2022, 43: 844-854. PMID: 34993558, PMCID: PMC8739007, DOI: 10.1007/s00246-021-02796-7.Peer-Reviewed Original ResearchConceptsMIS-C patientsAcute phaseChronic phaseInflammatory syndromeTwo-dimensional speckle tracking echocardiographySubclinical myocardial injuryCircumferential strainMultisystem inflammatory syndromeLeft ventricular dysfunctionSingle-institution reviewSpeckle tracking echocardiographyTwo-dimensional echocardiographyCoronavirus disease 2019Future adverse eventsVentricular function parametersBasal anterolateral segmentMean GCSVentricular dysfunctionAdverse eventsFractional shorteningSignificant sequelaeVentricular strainMyocardial dysfunctionGlobal longitudinalMyocardial injury
2020
De novo damaging variants associated with congenital heart diseases contribute to the connectome
Ji W, Ferdman D, Copel J, Scheinost D, Shabanova V, Brueckner M, Khokha MK, Ment LR. De novo damaging variants associated with congenital heart diseases contribute to the connectome. Scientific Reports 2020, 10: 7046. PMID: 32341405, PMCID: PMC7184603, DOI: 10.1038/s41598-020-63928-2.Peer-Reviewed Original ResearchMeSH KeywordsConnectomeDNA HelicasesDNA-Binding ProteinsExomeFemaleHeart Defects, CongenitalHistone-Lysine N-MethyltransferaseHomeodomain ProteinsHumansMaleMi-2 Nucleosome Remodeling and Deacetylase ComplexMutationMutation, MissenseMyeloid-Lymphoid Leukemia ProteinNerve Tissue ProteinsProtein Tyrosine Phosphatase, Non-Receptor Type 11Receptor, Notch1ConceptsDe novo variantsNDD genesCardiac patterningDe novo damaging variantsDamaging de novo variantsCHD genesDamaging variantsGenesProtein truncatingGenetic originNovo variantsGene mutationsPatterningRecent studiesDendritic developmentVariantsMutationsNeurogenesisSynaptogenesisBonferroni correction
2018
Fetal Echocardiographic Measures to Improve the Prenatal Diagnosis of Coarctation of the Aorta
Patel C, Weeks B, Copel J, Fahey J, Song X, Shabanova V, Ferdman DJ. Fetal Echocardiographic Measures to Improve the Prenatal Diagnosis of Coarctation of the Aorta. Pediatric Cardiology 2018, 1-9. PMID: 30547295, DOI: 10.1007/s00246-018-2040-3.Peer-Reviewed Original ResearchRapid Regression of Prenatally Identified Intrapericardial Giant Rhabdomyomas with Sirolimus
Patel C, Abraham S, Ferdman D. Rapid Regression of Prenatally Identified Intrapericardial Giant Rhabdomyomas with Sirolimus. Case 2018, 2: 258-261. PMID: 30582086, PMCID: PMC6302122, DOI: 10.1016/j.case.2018.07.003.Peer-Reviewed Original Research
2015
A Smartphone Application to Diagnose the Mechanism of Pediatric Supraventricular Tachycardia
Ferdman DJ, Liberman L, Silver ES. A Smartphone Application to Diagnose the Mechanism of Pediatric Supraventricular Tachycardia. Pediatric Cardiology 2015, 36: 1452-1457. PMID: 25958154, DOI: 10.1007/s00246-015-1185-6.Peer-Reviewed Original ResearchConceptsAtrioventricular nodal reentrant tachycardiaAtrioventricular reentrant tachycardiaSupraventricular tachycardiaPediatric patientsReentrant tachycardiaHolter monitorNodal reentrant tachycardiaPediatric supraventricular tachycardiaChi-square testSingle-lead ECGPediatric electrophysiologistsProspective studyRetrograde P wavesSVT mechanismTachycardia mechanismCorrect diagnosisPatientsPairs of sinusesTachycardiaSmartphone applicationECG
2014
Subcutaneous Treprostinil for Pulmonary Hypertension in Chronic Lung Disease of Infancy
Ferdman DJ, Rosenzweig EB, Zuckerman WA, Krishnan U. Subcutaneous Treprostinil for Pulmonary Hypertension in Chronic Lung Disease of Infancy. Pediatrics 2014, 134: e274-e278. PMID: 24982101, DOI: 10.1542/peds.2013-2330.Peer-Reviewed Original ResearchConceptsPulmonary arterial hypertensionChronic lung diseaseSevere pulmonary arterial hypertensionFormer premature infantsSubcutaneous treprostinilLung diseaseArterial hypertensionPulmonary hypertensionPremature infantsPersistent pulmonary arterial hypertensionIntravenous prostanoid therapySimilar hemodynamic effectsStandard respiratory careTargeted PAH therapyWeeks of therapyCatheter-related complicationsRight ventricular functionCentral venous accessSubgroup of patientsLife-threatening diseasePAH therapyProstanoid therapyConservative therapyHemodynamic effectsPreterm infants
2011
Common Atrium and Pulmonary Vascular Disease
Ferdman DJ, Brady D, Rosenzweig EB. Common Atrium and Pulmonary Vascular Disease. Pediatric Cardiology 2011, 32: 595-598. PMID: 21344289, DOI: 10.1007/s00246-011-9919-6.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsBiopsyCardiac CatheterizationChildChild, PreschoolEchocardiographyFemaleFollow-Up StudiesHeart AtriaHeart Defects, CongenitalHeart Septal Defects, AtrialHeart Septal Defects, VentricularHumansHypertension, PulmonaryInfantMalePulmonary ArteryVascular ResistanceYoung AdultConceptsPulmonary vascular diseaseVascular diseaseCommon atriumEarly pulmonary vascular diseaseSevere pulmonary vascular diseaseLarge atrial septal defectPulmonary hypertension therapyUnderwent surgical repairAtrial septal defectClinical courseSurgical repairCase seriesHypertension therapySeptal defectSurgical correctionPatientsDiseaseAtriumAge 2Early monitoringFirst yearTherapy
2010
Pulmonary Arterial Hypertension And Common Atrium
Ferdman D, Ramaswamy P, Rosenzweig E. Pulmonary Arterial Hypertension And Common Atrium. 2010, a6219-a6219. DOI: 10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a6219.Peer-Reviewed Original Research
2006
Defining, Navigating, and Negotiating Success: The Experiences of Mid‐Career Robert Wood Johnson Clinical Scholar Women
Kalet AL, Fletcher KE, Ferdman DJ, Bickell NA. Defining, Navigating, and Negotiating Success: The Experiences of Mid‐Career Robert Wood Johnson Clinical Scholar Women. Journal Of General Internal Medicine 2006, 21: 920-925. PMID: 16918735, PMCID: PMC1831601, DOI: 10.1111/j.1525-1497.2006.00524.x.Peer-Reviewed Original Research