1990
Yeast suppressor mutations and transfer RNA processing
Nichols M, Willis I, Söll D. Yeast suppressor mutations and transfer RNA processing. Methods In Enzymology 1990, 181: 377-394. PMID: 2199758, DOI: 10.1016/0076-6879(90)81137-j.Peer-Reviewed Original ResearchMeSH KeywordsBase SequenceBlotting, NorthernChromosomes, FungalGenes, FungalIndicators and ReagentsMolecular Sequence DataMutationNucleic Acid ConformationNucleic Acid HybridizationRNA Polymerase IIIRNA Processing, Post-TranscriptionalRNA, TransferRNA, Transfer, SerSaccharomyces cerevisiaeSuppression, GeneticTranscription FactorsTranscription, GeneticConceptsTRNA genesMature-sized tRNAsRNA processing reactionsPrimer-directed mutagenesisAminoacyl-tRNA synthetaseTransfer RNA moleculesCognate aminoacyl-tRNA synthetaseRNA processingSuppressor mutationsTRNA locusElongation factorProtein biosynthesisRibosomal interactionsRNA moleculesMutant strainStructural proteinsPink coloniesTranscription efficiencyProcessing reactionsProtein synthesisSuppressor functionTRNALow template concentrationsGenesLoci
1985
supN ochre suppressor gene in Escherichia coli codes for tRNALys
Uemura H, Thorbjarnardóttir S, Gamulin V, Yano J, Andrésson O, Söll D, Eggertsson G. supN ochre suppressor gene in Escherichia coli codes for tRNALys. Journal Of Bacteriology 1985, 163: 1288-1289. PMID: 3897192, PMCID: PMC219277, DOI: 10.1128/jb.163.3.1288-1289.1985.Peer-Reviewed Original Research
1979
Regulation of the biosynthesis of aminoacyl-transfer ribonucleic acid synthetases and of transfer ribonucleic acid in Escherichia coli. VI. Mutants with increased levels of glutaminyl-transfer ribonucleic acid synthetase and of glutamine transfer ribonucleic acid
Cheung A, Morgan S, Low K, Söll D. Regulation of the biosynthesis of aminoacyl-transfer ribonucleic acid synthetases and of transfer ribonucleic acid in Escherichia coli. VI. Mutants with increased levels of glutaminyl-transfer ribonucleic acid synthetase and of glutamine transfer ribonucleic acid. Journal Of Bacteriology 1979, 139: 176-184. PMID: 378954, PMCID: PMC216843, DOI: 10.1128/jb.139.1.176-184.1979.Peer-Reviewed Original ResearchConceptsTransfer ribonucleic acidAminoacyl-transfer ribonucleic acid synthetasesE. coli mapGlutaminyl-tRNA synthetaseRibonucleic acidTRNA-GlnStructural geneGenetic lociEscherichia coli strainsSpontaneous revertantsEscherichia coliParental strainThermolabile enzymeInteresting strainsColi strainsSynthetaseLociRevertantsEnzymeGlnMin 24GlnRStrainsTRNAMutantsRegulation of the biosynthesis of aminoacyl-transfer ribonucleic acid synthetases and of transfer ribonucleic acid in Escherichia coli. V. Mutants with increased levels of valyl-transfer ribonucleic acid synthetase
Baer M, Low K, Söll D. Regulation of the biosynthesis of aminoacyl-transfer ribonucleic acid synthetases and of transfer ribonucleic acid in Escherichia coli. V. Mutants with increased levels of valyl-transfer ribonucleic acid synthetase. Journal Of Bacteriology 1979, 139: 165-175. PMID: 378953, PMCID: PMC216842, DOI: 10.1128/jb.139.1.165-175.1979.Peer-Reviewed Original ResearchConceptsValyl-tRNA synthetaseAminoacyl-transfer ribonucleic acid synthetasesTransfer ribonucleic acidStructural geneProtein degradationEnzyme overproductionGenetic lociEscherichia coli strainsSpontaneous revertantsEscherichia coliThermolabile enzymeEnzyme synthesisSynthetaseNew enzyme synthesisColi strainsRibonucleic acidRevertantsTurnover rateSynthetasesMutantsBiosynthesisGenesLociColiEnzymeGlutamyl-γ-methyl ester acts as a methionine analogue in Escherichia coli: analogue resistant mutants map at the metJ and metK loci
Kraus J, Soll D, Low K. Glutamyl-γ-methyl ester acts as a methionine analogue in Escherichia coli: analogue resistant mutants map at the metJ and metK loci. Genetics Research 1979, 33: 49-55. PMID: 383574, DOI: 10.1017/s0016672300018152.Peer-Reviewed Original Research
1977
Regulation of biosynthesis of aminoacyl-tRNA synthetases and of tRNA in Escherichia coli II. Isolation of regulatory mutants affecting leucyl-tRNA synthetase levels
LaRossa R, Vögeli G, Low K, Söll D. Regulation of biosynthesis of aminoacyl-tRNA synthetases and of tRNA in Escherichia coli II. Isolation of regulatory mutants affecting leucyl-tRNA synthetase levels. Journal Of Molecular Biology 1977, 117: 1033-1048. PMID: 342703, DOI: 10.1016/s0022-2836(77)80011-9.Peer-Reviewed Original ResearchConceptsLeucyl-tRNA synthetaseThermolabile leucyl-tRNA synthetaseRegulation of biosynthesisDistinct genetic lociAminoacyl-tRNA synthetasesEscherichia coli IIOperator-promoter regionStructural geneRegulatory mutantsGenetic lociEscherichia coli strainsSuch revertantsSpontaneous revertantsThermolabile enzymeLociSynthetaseColi strainsRevertantsSynthetase levelsLeuTRNAMutantsSynthetasesLeuXBiosynthesis
1975
Isolation and partial characterization of three Escherichia coli mutants with altered transfer ribonucleic acid methylases
Marinus M, Morris N, Söll D, Kwong T. Isolation and partial characterization of three Escherichia coli mutants with altered transfer ribonucleic acid methylases. Journal Of Bacteriology 1975, 122: 257-265. PMID: 1091626, PMCID: PMC235665, DOI: 10.1128/jb.122.1.257-265.1975.Peer-Reviewed Original ResearchConceptsE. coli genomeEscherichia coli mutantsWild-type cellsEscherichia coli KAbility of RNAColi genomeColi mutantsAmber mutationGenetic lociMutagenized cellsColi KMutant strainMutantsLambda phageTRNAS-adenosylmethioninePartial characterizationGenomeCellsCrude enzymeBiosynthesisMethylasesMethylaseLociRNA