1994
Domains of E. Coli Glutaminyl-tRNA Synthetase Disordered in the Crystal Structure Are Essential for Function or Stability
Conley J, Sherman J, Thomann H, Söill D. Domains of E. Coli Glutaminyl-tRNA Synthetase Disordered in the Crystal Structure Are Essential for Function or Stability. Nucleosides Nucleotides & Nucleic Acids 1994, 13: 1581-1595. DOI: 10.1080/15257779408012173.Peer-Reviewed Original Research
1992
Aminoacyl-tRNA synthetase-induced cleavage of tRNA
Beresten S, Jahn M, Söll D. Aminoacyl-tRNA synthetase-induced cleavage of tRNA. Nucleic Acids Research 1992, 20: 1523-1530. PMID: 1579445, PMCID: PMC312233, DOI: 10.1093/nar/20.7.1523.Peer-Reviewed Original ResearchConceptsE. coli glutaminyl-tRNA synthetaseGlutaminyl-tRNA synthetaseAminoacyl-tRNA synthetasesPhosphodiester bond cleavageCognate tRNATRNAConformational changesPresence of Mg2Specific fashion
1991
Anticodon and acceptor stem nucleotides in tRNAGln are major recognition elements for E. coli glutaminyl-tRNA synthetase
Jahn M, Rogers M, Söll D. Anticodon and acceptor stem nucleotides in tRNAGln are major recognition elements for E. coli glutaminyl-tRNA synthetase. Nature 1991, 352: 258-260. PMID: 1857423, DOI: 10.1038/352258a0.Peer-Reviewed Original ResearchConceptsGlutaminyl-tRNA synthetaseMutant tRNAsE. coli glutaminyl-tRNA synthetaseEfficient amber suppressorsAminoacyl-tRNA synthetasesCorresponding transfer RNASet of nucleotidesMajor recognition elementGlutamine identityAcceptor stem regionTRNA discriminationTransfer RNAAmber suppressorProtein biosynthesisTRNA moleculesUnmodified tRNACorrect attachmentAnticodon regionTRNAAcceptor stemSimilar kinetic parametersEscherichia coliAmino acidsDifferent synthetasesSpecificity constant