1985
Functional analysis of fractionated Drosophila Kc cell tRNA gene transcription components.
Burke D, Söll D. Functional analysis of fractionated Drosophila Kc cell tRNA gene transcription components. Journal Of Biological Chemistry 1985, 260: 816-823. PMID: 3844013, DOI: 10.1016/s0021-9258(20)71171-3.Peer-Reviewed Original ResearchConceptsTranscription componentsTRNA genesDrosophila Kc cell extractFunctional analysisActive transcription complexesHuman HeLa cellsFactor BDrosophila systemTranscription initiationStable complex formationTranscription complexC associatesLarge complexesReconstitution experimentsCell extractsHeLa cellsCell factorFactor C.Factor CGenesStable complexesComplex formationPartial purificationComplexesDNA
1984
Transcriptionally active and inactive gene repeats within the D. meianogaster 5S RNA gene cluster
Sharp S, Garcia A, Cooley L, Söll D. Transcriptionally active and inactive gene repeats within the D. meianogaster 5S RNA gene cluster. Nucleic Acids Research 1984, 12: 7617-7632. PMID: 6093044, PMCID: PMC320189, DOI: 10.1093/nar/12.20.7617.Peer-Reviewed Original ResearchConceptsEfficiency of transcriptionRRNA gene copiesHigh transcription efficiencyTwo-nucleotide deletionD. melanogasterGene repeatRNA genesGene clusterPrimary transcriptGene copiesTranscription functionTranscription efficiencyTemplate activityCell extractsTranscriptionDNAPosition 28Position 86DNA typesRepeat unitsDeletionSame sequenceMelanogasterRRNAGenes
1982
Escherichia coli glutaminyl-tRNA synthetase. I. Isolation and DNA sequence of the glnS gene.
Yamao F, Inokuchi H, Cheung A, Ozeki H, Söll D. Escherichia coli glutaminyl-tRNA synthetase. I. Isolation and DNA sequence of the glnS gene. Journal Of Biological Chemistry 1982, 257: 11639-11643. PMID: 6288695, DOI: 10.1016/s0021-9258(18)33810-9.Peer-Reviewed Original ResearchOrganization and nucleotide sequence of nuclear 5S rRNA genes in yellow lupin ( Lupinus lutens )
Rafalski J, Wiewiorowski M, SÖll D. Organization and nucleotide sequence of nuclear 5S rRNA genes in yellow lupin ( Lupinus lutens ). Nucleic Acids Research 1982, 10: 7635-7642. PMID: 7155897, PMCID: PMC327035, DOI: 10.1093/nar/10.23.7635.Peer-Reviewed Original Research
1981
The initiator tRNA genes of Drosophila melanogaster: evidence for a tRNA pseudogene
Sharp S, DeFranco D, Silberklang M, Hosbach H, Schmidt T, Kubli E, Gergen J, Wensink P, Söll D. The initiator tRNA genes of Drosophila melanogaster: evidence for a tRNA pseudogene. Nucleic Acids Research 1981, 9: 5867-5882. PMID: 6273811, PMCID: PMC327570, DOI: 10.1093/nar/9.22.5867.Peer-Reviewed Original ResearchConceptsInitiator tRNA geneTRNA genesDrosophila genomeDrosophila melanogasterTRNA gene familyRNA polymerase IIIDrosophila melanogaster DNAKb DNA fragmentTRNA pseudogenesRepetitive DNAGene familyPolymerase IIISingle copyGenomic DNADNA fragmentsPseudogenesRepeat segmentsGenesHybridization analysisFourth cloneMelanogasterSitu hybridizationGenomeDNAFragments
1980
Analysis of a drosophila tRNA gene cluster
Hovemann B, Sharp S, Yamada H, Söll D. Analysis of a drosophila tRNA gene cluster. Cell 1980, 19: 889-895. PMID: 6769590, DOI: 10.1016/0092-8674(80)90080-x.Peer-Reviewed Original ResearchConceptsTRNA genesFlanking regionsTRNA gene clusterDrosophila tRNA genesTranscription control regionsSecondary structure featuresTranscription directionDrosophila DNAGene clusterMature tRNATRNALys geneControl regionDNA sequencesNucleotide sequenceConsensus sequenceGene regionKb fragmentTerminal sequenceGenesCol E1DNA strandsDNATRNAHybridization of DNASequence
1970
In Vitro Biosynthesis of Pseudouridine at the Polynucleotide Level by an Enzyme Extract from Escherichia coli
Johnson L, Söll D. In Vitro Biosynthesis of Pseudouridine at the Polynucleotide Level by an Enzyme Extract from Escherichia coli. Proceedings Of The National Academy Of Sciences Of The United States Of America 1970, 67: 943-950. PMID: 4943184, PMCID: PMC283296, DOI: 10.1073/pnas.67.2.943.Peer-Reviewed Original ResearchConceptsE. coli RNA polymeraseRNA transcription productsColi RNA polymeraseConversion of uridineE. coli extractsTRNA genesRNA polymerasePolynucleotide levelUridine residuesTranscription productsVitro BiosynthesisMycoplasma spEscherichia coliLambda DNARNADNAMacromolecular levelEnzyme extractBiosynthesisGenesPolymerasePseudouridineSpColiResidues