2011
tRNA import into mitochondria: many organisms but not so many mechanisms
Alfonzo J, Randau L, Söll D. tRNA import into mitochondria: many organisms but not so many mechanisms. The FASEB Journal 2011, 25: 311.3-311.3. DOI: 10.1096/fasebj.25.1_supplement.311.3.Peer-Reviewed Original ResearchTRNA importMitochondrial genomeMammalian mitochondriaImport of tRNAsMajority of eukaryotesMitochondrial tRNA mutationsProtein importImport pathwayTRNA genesImport systemAdditional tRNAsTRNA mutationsTRNACellular ATPMitochondriaEukaryotesOrganismsGenomeRat liver mitochondriaLiver mitochondriaImportInnate abilityGenesTrypanosomesCytoplasm
2000
Domain-specific recruitment of amide amino acids for protein synthesis
Tumbula D, Becker H, Chang W, Söll D. Domain-specific recruitment of amide amino acids for protein synthesis. Nature 2000, 407: 106-110. PMID: 10993083, DOI: 10.1038/35024120.Peer-Reviewed Original ResearchConceptsGlutaminyl-tRNA synthetaseAsparaginyl-tRNA synthetaseProtein synthesisAmino acidsAminoacyl-transfer RNAAmino acid metabolismGlu-tRNAGlnAsn-tRNAProtein biosynthesisGln-tRNAArchaeaTRNASynthetaseAmidotransferaseBacteriaAmidotransferasesDirect evidenceDifferent mechanismsBiosynthesisCentral importanceCrucial stepRNAOrganismsDomainCytoplasm
1974
15. Aminoacyl-tRNA Synthetases
Söll D, Schimmel P. 15. Aminoacyl-tRNA Synthetases. The Enzymes 1974, 10: 489-538. DOI: 10.1016/s1874-6047(08)60147-x.Peer-Reviewed Original ResearchAminoacyl-tRNA synthetasesEucaryotic organismsSpecific aminoacyl-tRNA synthetasesCorresponding cytoplasmic enzymesFamily of enzymesMitochondrial tRNAsProtein biosynthesisMammalian cellsMammalian virusesSynthetasesCytoplasmic enzymeSeparate proteinsCell extractsTRNAAmino acidsOrganismsCytoplasmSame organismEnzymeOrganellesMitochondriaMachineryProteinKey roleProcaryotes