2021
α-Fetoprotein mRNA in situ hybridisation is a highly specific marker of hepatocellular carcinoma: a multi-centre study
Lu SX, Huang YH, Liu LL, Zhang CZ, Yang X, Yang YZ, Shao CK, Li JM, Xie D, Zhang X, Jain D, Yun JP. α-Fetoprotein mRNA in situ hybridisation is a highly specific marker of hepatocellular carcinoma: a multi-centre study. British Journal Of Cancer 2021, 124: 1988-1996. PMID: 33824478, PMCID: PMC8184895, DOI: 10.1038/s41416-021-01363-4.Peer-Reviewed Original ResearchConceptsHepatocellular carcinomaHepatocytic lesionsDiagnosis of HCCLiver biopsy cohortHepatocyte paraffin 1Independent retrospective cohortsBenign liver lesionsMulti-center studyGood diagnostic valueNovel diagnostic biomarkersArginase-1 (Arg-1) proteinsΑ-fetoprotein mRNASurgical cohortRetrospective cohortBiopsy cohortHepPar-1Arg-1Liver lesionsDiagnostic biomarkersDiagnostic valueMalignancy lesionsLesionsGlypican3CohortSpecific markers
2016
Therapeutic Challenges of Hepatic Mucormycosis in Hematologic Malignancy: A Case Report and Review of the Literature
Bernardo RM, Gurung A, Jain D, Malinis MF. Therapeutic Challenges of Hepatic Mucormycosis in Hematologic Malignancy: A Case Report and Review of the Literature. American Journal Of Case Reports 2016, 17: 484-489. PMID: 27406045, PMCID: PMC4948661, DOI: 10.12659/ajcr.898480.Peer-Reviewed Case Reports and Technical NotesConceptsDual antifungal therapyAntifungal therapyHepatic mucormycosisSurgical resectionClinical presentationCase reportLiver lesionsIsolated hepatic mucormycosisTransplant-associated infectionsMultiple liver lesionsCombination antifungal therapyAcute myeloid leukemiaHigh mortality rateOptimal antifungal therapyGastrointestinal involvementInduction chemotherapyNeutropenic feverAbdominal painLymphoproliferative disordersTherapeutic challengeHematologic malignanciesCommon siteMyeloid leukemiaTreatment strategiesGastrointestinal tract