Gene expression profiling of ErbB receptor and ligand-dependent transcription
Amin DN, Perkins AS, Stern DF. Gene expression profiling of ErbB receptor and ligand-dependent transcription. Oncogene 2003, 23: 1428-1438. PMID: 14973552, DOI: 10.1038/sj.onc.1207257.Peer-Reviewed Original ResearchMeSH KeywordsBreast NeoplasmsErbB ReceptorsFemaleGene Expression ProfilingGene Expression Regulation, NeoplasticHumansLigandsOligonucleotide Array Sequence AnalysisReceptor, ErbB-2Receptor, ErbB-4Reverse Transcriptase Polymerase Chain ReactionTranscription, GeneticTumor Cells, CulturedUp-RegulationConceptsGene expression profilingExpression profilingInfluences gene transcriptionLigand-dependent transcriptionLigand-independent activationTranscriptional targetsGene transcriptionBreast cancerGene expressionMolecular mechanismsSame cell lineReceptor homodimersOligonucleotide arraysBreast cancer cellsUnidentified targetsErbB receptorsOverexpression of ErbB2GenesCancer cellsCell linesTranscriptionErbB4 receptorsErbB2ErbBClinical outcomes