Considerations in Controlling for Urine Concentration for Biomarkers of Kidney Disease Progression After Acute Kidney Injury
Wen Y, Thiessen-Philbrook H, Moledina DG, Kaufman JS, Reeves WB, Ghahramani N, Ikizler TA, Go AS, Liu KD, Siew ED, Himmelfarb J, Kimmel PL, Hsu CY, Parikh CR. Considerations in Controlling for Urine Concentration for Biomarkers of Kidney Disease Progression After Acute Kidney Injury. Kidney International Reports 2022, 7: 1502-1513. PMID: 35812275, PMCID: PMC9263319, DOI: 10.1016/j.ekir.2022.03.026.Peer-Reviewed Original ResearchAcute kidney injuryChronic kidney diseaseKidney injury molecule-1Urine concentrationsCKD outcomesKidney injuryInverse associationUrine kidney injury molecule-1Progression of CKDIncident chronic kidney diseaseCox proportional hazards regressionAcute Kidney Injury studyInjury molecule-1Kidney disease progressionProportional hazards regressionChemoattractant protein-1CKD progressionComposite outcomeNeutrophil gelatinaseInterleukin-18Urine biomarkersHazards regressionKidney diseaseSubsequent sequelaeUrinary concentrations