2022
Central and peripheral nervous system responses to chronic and paced hyperventilation in anxious and healthy subjects
Tolin D, O'Bryan E, Davies C, Diefenbach G, Johannesen J. Central and peripheral nervous system responses to chronic and paced hyperventilation in anxious and healthy subjects. Biological Psychology 2022, 176: 108472. PMID: 36481266, PMCID: PMC9839632, DOI: 10.1016/j.biopsycho.2022.108472.Peer-Reviewed Original ResearchConceptsAnxious patientsCentral nervous system correlatesPeripheral nervous system responsesAlpha-1 powerPeripheral nervous systemFurther treatment developmentNervous system responsesHealthy control participantsHypocapnic patientsNormocapnic patientsChronic hyperventilationRespiratory distressEEG abnormalitiesHealthy subjectsSkin conductance levelNervous systemPatientsControl groupHealthy participantsPoor toleranceTreatment developmentSkin conductance response amplitudeControl participantsBreathing taskMechanistic target
2021
Psychophysiological assessment of stress reactivity and recovery in anxiety disorders
Tolin DF, Lee E, Levy HC, Das A, Mammo L, Katz BW, Diefenbach GJ. Psychophysiological assessment of stress reactivity and recovery in anxiety disorders. Journal Of Anxiety Disorders 2021, 82: 102426. PMID: 34022509, DOI: 10.1016/j.janxdis.2021.102426.Peer-Reviewed Original ResearchConceptsGeneralized anxiety disorderCognitive behavioral therapyAnxiety disordersPanic disorderStressor phaseCBT outcomeHigh-frequency heart rate variabilityFrequency heart rate variabilityPsychophysiological reactivityEnd-tidal CODSM-5 anxiety disordersSpecialty outpatient clinicsHealthy control participantsHeart rate variabilityAdult patientsOutpatient clinicRate recoveryPatientsReactivity phaseResting phaseAnxious patientsAutonomic recoveryRate variabilityControl participantsDiminished changes