Glutamate Excitotoxicity in Multiple Sclerosis
Pitt D, Raine C. Glutamate Excitotoxicity in Multiple Sclerosis. 2004, 285-303. DOI: 10.1007/978-1-4419-8959-8_16.Peer-Reviewed Original ResearchGlutamate excitotoxicityMultiple sclerosisWhite matter injuryCentral white matterProminent demyelinationMS pathogenesisOligodendrocyte damageInflammatory demyelinationOligodendrocyte lossExtracellular glutamateGlutamate homeostasisAnimal modelsExcitotoxicityWhite matterCell targetsClearance pathwaysCommon pathwayDisease mechanismsCell culture studiesDemyelinationSclerosisRecent dataOligodendrocytesCulture studiesPathogenesis