2011
Projected Survival Gains from Revising State Laws Requiring Written Opt-in Consent for HIV Testing
April MD, Chiosi JJ, Paltiel AD, Sax PE, Walensky RP. Projected Survival Gains from Revising State Laws Requiring Written Opt-in Consent for HIV Testing. Journal Of General Internal Medicine 2011, 26: 661-667. PMID: 21286837, PMCID: PMC3101973, DOI: 10.1007/s11606-011-1637-5.Peer-Reviewed Original ResearchConceptsPotential survival gainsSurvival gainHIV testingDiagnosis rateAnnual HIV incidenceProportion of HIVUndiagnosed HIV prevalenceAnnual HIV diagnosis ratesHIV diagnosis ratesHIV incidenceHIV prevalenceEarly diagnosisHIVDisease controlLYGSurveillance dataAdult personsConsentConsent methodsPersonsPatientsConsent lawsBackgroundAlthoughDesignWeObjectiveTo
2009
Medical decision making in patients with knee pain, meniscal tear, and osteoarthritis
Suter LG, Fraenkel L, Losina E, Katz JN, Gomoll AH, Paltiel AD. Medical decision making in patients with knee pain, meniscal tear, and osteoarthritis. Arthritis & Rheumatism 2009, 61: 1531-1538. PMID: 19877094, PMCID: PMC2804854, DOI: 10.1002/art.24893.Peer-Reviewed Original ResearchConceptsArthroscopic partial meniscectomyMeniscal tearsKnee painInternational Knee Documentation Committee scoreMagnetic resonance imaging (MRI) indicatorsObtainable clinical informationDegenerative meniscal tearsIndividuals ages 45Mean incremental gainIKDC scoreNonoperative managementAge 45Preoperative informationPartial meniscectomyClinical informationOsteoarthritisPainTearsLower likelihoodHigher likelihoodAlternative thresholdsMedical decisionsScoresIncremental gainPatientsPrice, Performance, and the FDA Approval Process: The Example of Home HIV Testing
Paltiel AD, Pollack HA. Price, Performance, and the FDA Approval Process: The Example of Home HIV Testing. Medical Decision Making 2009, 30: 217-223. PMID: 19429837, PMCID: PMC2897074, DOI: 10.1177/0272989x09334420.Peer-Reviewed Original ResearchMeSH KeywordsDevice ApprovalHIV InfectionsHumansPredictive Value of TestsReagent Kits, DiagnosticUnited StatesUnited States Food and Drug Administration
2002
A novel approach to defining the relationship between lung function and symptom status in asthma
Kuntz KM, Kitch BT, Fuhlbrigge AL, Paltiel AD, Weiss ST. A novel approach to defining the relationship between lung function and symptom status in asthma. Journal Of Clinical Epidemiology 2002, 55: 11-18. PMID: 11781117, DOI: 10.1016/s0895-4356(01)00412-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAsthmaClinical Trials as TopicForced Expiratory VolumeHumansLinear ModelsPredictive Value of TestsSeverity of Illness IndexConceptsAsthma-related symptomsLung functionMean lung functionAverage baseline valuePopulation-wide basisExpiratory volumeSymptom daysSymptom scoresNighttime awakeningsSymptom statusClinical trialsMean changeBaseline valuesLinear regression analysisSymptomsRegression analysisNegative associationOverall improvementAssociationAsthmaConsistent relationshipTrials
2001
Preevaluation of Clinical Trial Data: The Case of Preemptive Cytomegalovirus Therapy in Patients with Human Immunodeficiency Virus
Paltiel A, Goldie S, Losina E, Weinstein M, Seage G, Kimmel A, Zhang H, Freedberg K. Preevaluation of Clinical Trial Data: The Case of Preemptive Cytomegalovirus Therapy in Patients with Human Immunodeficiency Virus. Clinical Infectious Diseases 2001, 32: 783-793. PMID: 11229847, DOI: 10.1086/319223.Peer-Reviewed Original ResearchMeSH KeywordsAIDS-Related Opportunistic InfectionsAntiviral AgentsChemopreventionCost-Benefit AnalysisCytomegalovirusCytomegalovirus InfectionsGanciclovirHIV InfectionsHumansModels, BiologicalPolymerase Chain ReactionPredictive Value of TestsQuality-Adjusted Life YearsSensitivity and SpecificityValganciclovirConceptsHuman immunodeficiency virusDuration of survivalPreemptive therapyCMV casesImmunodeficiency virusCMV polymerase chain reactionEnd-stage HIV diseaseUpcoming trialsCMV preemptive therapySalvage antiretroviral therapyCells/microLClinical trial dataCMV prophylaxisAntiretroviral therapyHIV diseaseComplication rateEfficacy assumptionsPolymerase chain reactionDisease progressionClinical uncertaintyDrug effectsPatientsTrial dataTherapyChain reaction