2015
High-dose and fractionation effects in stereotactic radiation therapy: Analysis of tumor control data from 2965 patients
Shuryak I, Carlson DJ, Brown JM, Brenner DJ. High-dose and fractionation effects in stereotactic radiation therapy: Analysis of tumor control data from 2965 patients. Radiotherapy And Oncology 2015, 115: 327-334. PMID: 26058991, DOI: 10.1016/j.radonc.2015.05.013.Peer-Reviewed Original ResearchConceptsMulti-fraction stereotactic radiotherapyStereotactic radiotherapyTumoricidal mechanismsTumor controlHigh dosesSingle-dose stereotactic radiotherapySingle-fraction treatmentStereotactic radiation therapyTumor control dataBrain metastasesLung tumorsSRT patientsRadiation therapyTreatment dosesLow dosesSRT treatmentDosesLinear-quadratic modelPatientsFraction numberTreatmentLung dataLQ modelControl dataMetastasis
2008
SU‐GG‐T‐509: Impact of Gating On Dose Escalation in Lung Cancer Patients
Antony J, Loo B, Carlson D, Maxim P, Luxton G, Xing L. SU‐GG‐T‐509: Impact of Gating On Dose Escalation in Lung Cancer Patients. Medical Physics 2008, 35: 2842-2842. DOI: 10.1118/1.2962258.Peer-Reviewed Original ResearchNormal tissue complication probabilityDose escalationTumor marginsInferior tumor marginMean lung doseLocal tumor controlLung cancer patientsTreatment planningConformal radiation therapyTumor motionTumor control probability modelCRT plansLeft lungMediastinal tumorLung doseTumor controlCancer patientsToxicity CriteriaLung tumorsRadiation therapyDose changesLyman-KutcherBurman modelDose constraintsPatients
2006
Effects of oxygen on intrinsic radiation sensitivity: A test of the relationship between aerobic and hypoxic linear‐quadratic (LQ) model parametersa)
Carlson DJ, Stewart RD, Semenenko VA. Effects of oxygen on intrinsic radiation sensitivity: A test of the relationship between aerobic and hypoxic linear‐quadratic (LQ) model parametersa). Medical Physics 2006, 33: 3105-3115. PMID: 17022202, DOI: 10.1118/1.2229427.Peer-Reviewed Original ResearchConceptsSurvival dataHypoxic cellsOxygen enhancement ratioPatient survival dataIntrinsic radiation sensitivityPoor treatment prognosisSublethal damage repairTumor controlHypoxic subvolumesCervix cancerClinical dataRadiosensitivity parametersTreatment prognosisAerobic cellsDoseDecreased sensitivityHypoxiaEnhancement ratioHypoxicTumorsAlpha/CellsLow-LET radiationTumor regionRadiation sensitivity