1994
Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis.
Zhang J, Markovic-Plese S, Lacet B, Raus J, Weiner HL, Hafler DA. Increased frequency of interleukin 2-responsive T cells specific for myelin basic protein and proteolipid protein in peripheral blood and cerebrospinal fluid of patients with multiple sclerosis. Journal Of Experimental Medicine 1994, 179: 973-984. PMID: 7509366, PMCID: PMC2191414, DOI: 10.1084/jem.179.3.973.Peer-Reviewed Original ResearchConceptsMyelin-reactive T cellsFrequency of MBPMBP-reactive T cell linesMBP-reactive T cellsMyelin basic proteinT cellsCerebrospinal fluidT cell linesMS patientsProteolipid proteinPLP-reactive T cellsNormal individualsFrequency of interleukinAutoreactive T cellsPathogenesis of MSMultiple sclerosis patientsIL-2-responsive cellsRIL-2 stimulationCentral nervous systemCell linesBasic proteinSclerosis patientsMultiple sclerosisPeripheral bloodPathogenic role
1990
Review of immunology.
Hafler DA. Review of immunology. Proceedings Of The Association For Research In Nervous And Mental Disease 1990, 68: 23-35. PMID: 2183313.Peer-Reviewed Original Research
1986
Monoclonal gammopathy and neuropathy: myelin-associated glycoprotein reactivity and clinical characteristics.
Hafler D, Johnson D, Kelly J, Panitch H, Kyle R, Weiner H. Monoclonal gammopathy and neuropathy: myelin-associated glycoprotein reactivity and clinical characteristics. Neurology 1986, 36: 75-8. PMID: 2417161, DOI: 10.1212/wnl.36.1.75.Peer-Reviewed Original ResearchConceptsMonoclonal gammopathySevere sensory-motor neuropathyAnti-MAG reactivityDistinct clinical entitySensory-motor neuropathyIgM monoclonal gammopathyClinical characteristicsMotor neuropathySensory neuropathyClinical entityGlycoprotein reactivityPatientsGammopathyNeuropathyImmunoblot analysisMyelinPolyneuropathySerum