1995
Tropical spastic paraparesis on the Caribbean coast of Colombia.
Dangond F, Daza JS, Rosania A, Quin MJ, Zaninovic V, Chaplin B, Marlink R, Hafler DA. Tropical spastic paraparesis on the Caribbean coast of Colombia. American Journal Of Tropical Medicine And Hygiene 1995, 52: 155-8. PMID: 7872443, DOI: 10.4269/ajtmh.1995.52.155.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCase-Control StudiesColombiaFemaleHTLV-I AntibodiesHumansMaleNeurologic ExaminationParaparesis, Tropical SpasticConceptsTropical spastic paraparesisSpastic paraparesisHuman T-cell lymphotropic virus type 1Chronic spastic paraparesisProgressive leg weaknessVirus type 1Enzyme-linked immunosorbent assayChronic myelopathySerum positivityLeg weaknessRetroviral diseaseParaparesisType 1Western blotImmunosorbent assayPatientsEthnic originFirst reportMyelopathyDiseaseAntibodies
1992
T-cell activation by autologous human T-cell leukemia virus type I-infected T-cell clones.
Wucherpfennig KW, Höllsberg P, Richardson JH, Benjamin D, Hafler DA. T-cell activation by autologous human T-cell leukemia virus type I-infected T-cell clones. Proceedings Of The National Academy Of Sciences Of The United States Of America 1992, 89: 2110-2114. PMID: 1549569, PMCID: PMC48606, DOI: 10.1073/pnas.89.6.2110.Peer-Reviewed Original ResearchConceptsIntercellular cell adhesion moleculeBlood T cellsT cell clonesT cell activationIL-2 receptorT cellsActivated T cellsHuman T-cell leukemia virus type I (HTLV-I) carriersSuch activated T cellsHAM/TSP patientsMyelopathy/tropical spastic paraparesisClass II major histocompatibility complex moleculesHAM/TSPChronic inflammatory diseaseExogenous interleukin-2HTLV-I infectionTropical spastic paraparesisMajor histocompatibility complex moleculesHuman T-cell leukemia virus type IVirus type IHistocompatibility complex moleculesCD2/LFATSP patientsSpastic paraparesisSpontaneous proliferation