1988
Oligoclonal T lymphocytes in the cerebrospinal fluid of patients with multiple sclerosis.
Hafler DA, Duby AD, Lee SJ, Benjamin D, Seidman JG, Weiner HL. Oligoclonal T lymphocytes in the cerebrospinal fluid of patients with multiple sclerosis. Journal Of Experimental Medicine 1988, 167: 1313-1322. PMID: 3258624, PMCID: PMC2188923, DOI: 10.1084/jem.167.4.1313.Peer-Reviewed Original ResearchMeSH KeywordsCerebrospinal FluidClone CellsHerpes ZosterHumansMeningoencephalitisMultiple SclerosisReceptors, Antigen, T-CellSubacute Sclerosing PanencephalitisT-LymphocytesConceptsT cell clonesT cell populationsOligoclonal T-cell populationsTCR gene rearrangement patternsCerebrospinal fluidGene rearrangement patternsCell clonesT cellsRearrangement patternsChronic progressive multiple sclerosis patientsProgressive multiple sclerosis patientsCell populationsChronic progressive MSHerpes zoster meningoencephalitisOligoclonal T lymphocytesOligoclonal T cellsT cell responsesMultiple sclerosis patientsCentral nervous systemT cell receptor beta chainTCR gene rearrangementsIndividual T cellsProgressive MSGamma chain geneImmune compartment
1987
Functional gamma chain-associated T cell receptors on cerebrospinal fluid-derived natural killer-like T cell clones.
Ang SL, Seidman JG, Peterman GM, Duby AD, Benjamin D, Lee SJ, Hafler DA. Functional gamma chain-associated T cell receptors on cerebrospinal fluid-derived natural killer-like T cell clones. Journal Of Experimental Medicine 1987, 165: 1453-1458. PMID: 3106557, PMCID: PMC2188318, DOI: 10.1084/jem.165.5.1453.Peer-Reviewed Original ResearchMeSH KeywordsCerebrospinal FluidClone CellsHumansImmunoglobulin gamma-ChainsKiller Cells, NaturalReceptors, Antigen, T-CellSubacute Sclerosing PanencephalitisConceptsAnti-CD3 mAbT cell clonesCerebrospinal fluidCell clonesIndependent T cell clonesNK-like activityHuman immune responseT cell receptorWT-31IL-2T cellsImmune responseIntracellular calciumCell receptorMAbsTcR gamma proteinGamma proteinSepharose beadsCell surfacePhenotypic analysisCD8CD4PanencephalitisSubacutePatients