Metabolic and behavioral deficits following a routine surgical procedure in rats
Frumberg DB, Fernando MS, Lee DE, Biegon A, Schiffer WK. Metabolic and behavioral deficits following a routine surgical procedure in rats. Brain Research 2007, 1144: 209-218. PMID: 17346680, PMCID: PMC2720638, DOI: 10.1016/j.brainres.2007.01.134.Peer-Reviewed Original ResearchConceptsMetabolic deficitsSensory cortexGeneral locomotionNovel object recognition testInjury-related deficitsSignificant metabolic deficitsSurgical brain injuryTime pointsCortical glucose metabolismPrimary motor cortexSerial imaging studiesRoutine surgical proceduresObject recognition testVoxel-based analysisIpsilateral cortexMotor cortexUnilateral decreaseBrain injuryContralateral hemisphereSurgical proceduresBehavioral deficitsFrontal cortexIpsilateral areasControl animalsDorsal striatum