2024
Quo vadis autoimmune hepatitis? - Summary of the 5th international autoimmune hepatitis group research workshop 2024
Engel B, Assis D, Bhat M, Clusmann J, Joostrenth, Gerussi A, Londoño M, Oo Y, Schregel I, Sebode M, Taubert R, Diseases I. Quo vadis autoimmune hepatitis? - Summary of the 5th international autoimmune hepatitis group research workshop 2024. JHEP Reports 2024, 101265. DOI: 10.1016/j.jhepr.2024.101265.Peer-Reviewed Original ResearchAutoimmune hepatitisInternational AIH GroupLiver transplant-free survivalAlternative first-lineCAR-T cellsRare chronic liver diseaseTransplant-free survivalDrug-induced autoimmunityChronic autoimmune responseEuropean Reference NetworkImmune-mediated diseasesChronic liver diseaseInitiative clinical trialsInflammatory bowel diseaseDecreased quality of lifeAIH patientsSalvage therapyRemission rateFirst-lineAIH groupT cellsStandard treatmentAutoimmune responseB cellsExpert centers
2020
AS055 Co-culture of bile-derived organoids from primary sclerosing cholangitis patients with CD4+ T cells replicates pathogenic, CCL20 dependent biliary-immune interactions
Soroka C, Roberts S, Hohenester S, Boyer J, Assis D. AS055 Co-culture of bile-derived organoids from primary sclerosing cholangitis patients with CD4+ T cells replicates pathogenic, CCL20 dependent biliary-immune interactions. Journal Of Hepatology 2020, 73: s41. DOI: 10.1016/s0168-8278(20)30634-6.Peer-Reviewed Original Research
2019
The Contribution of B Cells in Autoimmune Liver Diseases
Taylor SA, Assis DN, Mack CL. The Contribution of B Cells in Autoimmune Liver Diseases. Seminars In Liver Disease 2019, 39: 422-431. PMID: 31226726, PMCID: PMC6800599, DOI: 10.1055/s-0039-1688751.BooksConceptsAutoimmune liver diseaseT cell activationB cellsLiver diseaseT cellsCell activationB-cell mechanismsRegulatory T cellsProduction of autoantibodiesAutoreactive T cellsAutoreactive B cellsGeneration of cytokinesAutoimmune hepatitisCell mechanismsAntigen presentationDisease pathogenesisAutoantibodiesDiseaseCellsActivationVast majorityHepatitisCholangiopathyAutoimmunityCytokines