Sustained Activation of Extracellular Signal‐Regulated Kinase (ERK) Signaling in Human Prostate Cancer LNCaP Cells Depleted of Androgen
Drew L, Fine R, Raffo A, Petrylak D. Sustained Activation of Extracellular Signal‐Regulated Kinase (ERK) Signaling in Human Prostate Cancer LNCaP Cells Depleted of Androgen. The Prostate Journal 2001, 3: 105-117. DOI: 10.1046/j.1525-1411.2001.32003.x.Peer-Reviewed Original ResearchHuman prostate cancer LNCaP cellsERK phosphorylationMitogen-activated protein kinase cascadeProstate cancer LNCaP cellsProtein kinase cascadeC-Jun N-terminal kinaseMAPK kinase activityPhosphorylation/activityLNCaP cellsProtein levelsN-terminal kinaseMEK inhibitor U0126Formation of neuritesTyrosine kinase receptorsKinase cascadeExtracellular signalsAndrogen-sensitive human prostate cancer LNCaP cellsPhosphorylation statusKinase activityPotential role