2018
PET imaging reveals lower kappa opioid receptor availability in alcoholics but no effect of age
Vijay A, Cavallo D, Goldberg A, de Laat B, Nabulsi N, Huang Y, Krishnan-Sarin S, Morris ED. PET imaging reveals lower kappa opioid receptor availability in alcoholics but no effect of age. Neuropsychopharmacology 2018, 43: 2539-2547. PMID: 30188515, PMCID: PMC6224533, DOI: 10.1038/s41386-018-0199-1.Peer-Reviewed Original ResearchConceptsHealthy control cohortVolume of distributionOpioid receptor systemKappa-opioid receptorsOpioid receptorsDelta opioid receptor systemReceptor systemMu-opioid receptor systemOpioid receptor availabilityPotential pharmacological targetEffect of ageAge-related declineControl cohortPET scansAntagonist tracersReceptor availabilityMultivariate analysisPharmacological targetsPET imagingReceptorsAgePartial volume correctionCohortVT valuesPresent study
2014
First Drink to First Drunk: Age of Onset and Delay to Intoxication Are Associated with Adolescent Alcohol Use and Binge Drinking
Morean ME, Kong G, Camenga DR, Cavallo DA, Connell C, Krishnan‐Sarin S. First Drink to First Drunk: Age of Onset and Delay to Intoxication Are Associated with Adolescent Alcohol Use and Binge Drinking. Alcohol Clinical And Experimental Research 2014, 38: 2615-2621. PMID: 25257574, PMCID: PMC4211959, DOI: 10.1111/acer.12526.Peer-Reviewed Original Research
2005
Daily patterns of alcohol, cigarette, and marijuana use in adolescent smokers and nonsmokers
Duhig AM, Cavallo DA, McKee SA, George TP, Krishnan-Sarin S. Daily patterns of alcohol, cigarette, and marijuana use in adolescent smokers and nonsmokers. Addictive Behaviors 2005, 30: 271-283. PMID: 15621398, DOI: 10.1016/j.addbeh.2004.05.016.Peer-Reviewed Original ResearchConceptsFrequent daily useAdolescent smokersMarijuana useAdolescent cigarette smokersDaily usePatterns of alcoholMale smokersCigarette smokersSmokersClinical interventionsNonsmokersFuture researchPast monthMarijuanaMore daysSame dayCigarettesSignificant differencesOne-fifthDaily use patternsDaysMonths