2020
Acute encephalopathy with elevated CSF inflammatory markers as the initial presentation of COVID-19
Farhadian S, Glick LR, Vogels CBF, Thomas J, Chiarella J, Casanovas-Massana A, Zhou J, Odio C, Vijayakumar P, Geng B, Fournier J, Bermejo S, Fauver JR, Alpert T, Wyllie AL, Turcotte C, Steinle M, Paczkowski P, Dela Cruz C, Wilen C, Ko AI, MacKay S, Grubaugh ND, Spudich S, Barakat LA. Acute encephalopathy with elevated CSF inflammatory markers as the initial presentation of COVID-19. BMC Neurology 2020, 20: 248. PMID: 32552792, PMCID: PMC7301053, DOI: 10.1186/s12883-020-01812-2.Peer-Reviewed Original ResearchConceptsInitial presentationCentral nervous system inflammationSARS-CoV-2 infectionCSF inflammatory markersNervous system inflammationCerebrospinal fluid (CSF) cytokinesSeizure-like activityCOVID-19 infectionVirus SARS-CoV-2COVID-19SARS-CoV-2BackgroundCOVID-19Inflammatory markersNeurologic complicationsSystem inflammationImmunocompromised womanNeurologic manifestationsNeurologic symptomsViral neuroinvasionCase presentationWeInfected patientsMental statusRespiratory pathogensConclusionOur findingsInflammation
2015
Markers of Intestinal Inflammation for the Diagnosis of Infectious Gastroenteritis
Gonzalez MD, Wilen CB, Burnham CA. Markers of Intestinal Inflammation for the Diagnosis of Infectious Gastroenteritis. Clinics In Laboratory Medicine 2015, 35: 333-344. PMID: 26004646, DOI: 10.1016/j.cll.2015.02.001.Peer-Reviewed Original ResearchConceptsInfectious gastroenteritisIntestinal inflammationSystemic biomarkersInfectious diarrheaInvasive testingFecal biomarkersParasitic infectionsHost responseMajor causeGastroenteritisDiagnosisAdjunct diagnosticsStand-alone testsBiomarkersAssaysInexpensive assayMorbidityDiarrheaInflammationTherapyInfection